anti-Splicing Factor Proline/glutamine-Ric (SFPQ) Antibodies

FGF-induced protein related to a family of RNA- and DNA-binding proteins. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SFPQ 71514 Q8VIJ6
SFPQ 6421 P23246
SFPQ 252855  
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Top anti-SFPQ Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SFPQ Antibody Titration:  1.25ug/ml  ELISA Titer:  1:12500  Positive Control:  HepG2 cell lysate. SFPQ is strongly supported by BioGPS gene expression data to be expressed in HepG2 Rabbit Anti-SFPQ Antibody  Paraffin Embedded Tissue: Human Skin Cellular Data: Squamous epithelial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$249.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: SFPQ Antibody [NBP2-20329] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa D: HepG2 7. 5% SDS PAGE gel, diluted at 1:10000. Immunohistochemistry-Paraffin: SFPQ Antibody [NBP2-20329] - Immunohistochemical analysis of paraffin-embedded Hela xenograft, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SFPQ Antibody Titration:  5.0ug/ml  Positive Control:  Jurkat cell lysate SFPQ is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit Anti-SFPQ Antibody  Paraffin Embedded Tissue: Human Muscle Cellular Data: Skeletal muscle cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$249.00
Details
Human Rabbit Un-conjugated WB SFPQ Antibody (C-term) (ABIN657824) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the SFPQ antibody detected the SFPQ protein (arrow). All lanes : Anti-SFPQ Antibody (C-term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: NCI-H460 whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: A431 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 76 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Log in to see 10 to 11 Days
$385.00
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using SFPQ antibody. 100 μL Log in to see 13 to 14 Days
$393.25
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SFPQ on formalin-fixed paraffin-embedded human thyroid nodular goiter. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to SFPQ on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11 to 12 Days
$440.00
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-SFPQ antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$561.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: SFPQ Antibody [NBP2-49147] - Staining of human kidney shows strong nuclear positivity in cells in renal tubules and glomeruli. Immunocytochemistry/Immunofluorescence: SFPQ Antibody [NBP2-49147] - Analysis of human cell line U-2 OS shows positivity in nucleus but excluded from the nucleoli. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details

Top referenced anti-SFPQ Antibodies

  1. Human Monoclonal SFPQ Primary Antibody for IF, IHC (p) - ABIN562836 : Melton, Jackson, Wang, Lynch: Combinatorial control of signal-induced exon repression by hnRNP L and PSF. in Molecular and cellular biology 2007 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SFPQ Primary Antibody for ELISA, WB - ABIN520131 : Yarosh, Tapescu, Thompson, Qiu, Mallory, Fu, Lynch: TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. in Nucleic acids research 2015 (PubMed)

  3. Human Polyclonal SFPQ Primary Antibody for ICC, IF - ABIN253184 : Takayama, Horie-Inoue, Katayama, Suzuki, Tsutsumi, Ikeda, Urano, Fujimura, Takagi, Takahashi, Homma, Ouchi, Aburatani, Hayashizaki, Inoue: Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer. in The EMBO journal 2013 (PubMed)

More Antibodies against SFPQ Interaction Partners

Mouse (Murine) Splicing Factor Proline/glutamine-Ric (SFPQ) interaction partners

  1. SFPQ intron retention and nuclear loss are molecular hallmarks of familial and sporadic of amyotrophic lateral sclerosis.

  2. Results indicate that an splicing factor proline-glutamine rich protein (Sfpq)-dependent strategy for controlling miRNA activity takes place in cells, contributing to the complexity of miRNA-dependent gene expression control.

  3. data demonstrate that SFPQ orchestrates spatial gene expression of a newly identified RNA regulon essential for axonal viability.

  4. These results are compatible with the idea that SFPQ, plays an important role regulating proliferation and migration during the development of the cerebral cortex.

  5. these results show that PSF can repress the transcriptional activation of VEGF stimulated by IGF-1 via recruitment of the Hakai complex

  6. Quantitative proteomics reveals dynamic interaction of JNK with RNA transport granule proteins Sfpq and Nono during neuronal differentiation

  7. A protein complex was identified containing PSPC1, PSF and LMX1B, suggesting the existence of this complex in mesodiencephalic dopaminergic neurons.

  8. PSF contributes to the stability of a subset of histone genes and that loss of H2AE expression in the PSF-deficient thymocytes uniquely contributes to an increase in thymic apoptosis.

  9. analysis indicates PSF within the PER complex recruits SIN3A, a scaffold for assembly of transcriptional inhibitory complexes, and the PER complex thereby rhythmically delivers histone deacetylases to the Per1 promoter, which repress Per1 transcription

  10. Basal and cyclic AMP-induced Rbp4 transcription is regulated by a multiprotein complex that is similar to ones that modulate expression of genes of steroid hormone biosynthesis.

  11. identified as a protein kinase Calpha-binding protein in the cell nucleus

  12. PSPC1, NONO, and SFPQ form complexes with each other in Sertoli cells and may regulate androgen receptor-mediated transcriptional activity

  13. Hippocampal mRNA expression of Psf is up-regulated during contextual fear memory formation in both sexes as a specific result of the context/tone-shock association. Changes in splicing factor expression during LTM formation regulate alternative splicing.

  14. PSF binds to the proto-oncogene Rab23, repressing transcription

  15. These data from zebrafish indicate that, in vertebrates, sfpq plays a key role in neuronal development and is essential for normal brain development.

Zebrafish Splicing Factor Proline/glutamine-Ric (SFPQ) interaction partners

  1. we report the surprising finding that zebrafish respond to optic nerve lesion by inducing the expression of Sfpq and Socs3a

  2. sfpq function is required for differentiation, but not for determination, of specific classes of brain neurons.

Human Splicing Factor Proline/glutamine-Ric (SFPQ) interaction partners

  1. SFPQ dislocation was found enhanced with tau co-transfection and tau co-transfection further resulted in extended DNA disorganization in N2a cells. Overall, our results indicate that dysregulation and dislocation of SFPQ and subsequent DNA disorganization might be a novel pathway in the progression of Alzheimer's disease and frontotemporal dementia.

  2. Analytical ultracentrifugation to estimate the dimerization equilibrium of the SFPQ-containing dimers revealed that the SFPQ-containing dimers dissociate at low micromolar concentrations and that the heterodimers have higher affinities than the homodimer. Moreover, we observed that the apparent dissociation constant for the SFPQ/PSPC1 heterodimer was over 6-fold lower than that of the SFPQ/NONO heterodimer.

  3. SFPQ intron retention and nuclear loss are molecular hallmarks of familial and sporadic of amyotrophic lateral sclerosis.

  4. Vault RNAs partially induces drug resistance of human tumor cells MCF-7 by binding to the RNA/DNA-binding protein PSF and inducing oncogene GAGE6

  5. GAPLINC has a role in promoting colorectal cancer invasion via binding to PSF/NONO and partly by stimulating the expression of SNAI2

  6. PSF was found to be an important internal ribosome entry site trans acting factor (ITAF) for efficient translation of coxsackievirus B3 RNA.

  7. Mechanistic dissection reveals that NEAT1 broadly interacts with the NONO-PSF heterodimer as well as many other RNA-binding proteins and that multiple RNA segments in NEAT1, including a 'pseudo pri-miRNA' near its 3' end, help attract the Drosha-DGCR8 Microprocessor.

  8. The SFPQ*NONO complex contains an RNA binding domain, and prior work has demonstrated diverse roles in RNA metabolism. It is thus plausible that the additional repair function of NONO, revealed in cell-based assays, could involve RNA interaction.

  9. Describe the unusual morphology and expanded the morphologic spectrum of SFPQ/PSF-TFE3 renal cell carcinomas.

  10. The data suggest a model in which TRAP150 interacts with dimeric PSF to block access of RNA to RRM2, thereby regulating the activity of PSF toward a broad set of splicing events in T cells.

  11. PSF/SFPQ is a very common gene fusion partner in TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas) and melanotic Xp11 translocation renal cancers.

  12. coiled-coil interaction motif thus provides a molecular explanation for the functional aggregation of SFPQ that directs its role in regulating many aspects of cellular nucleic acid metabolism

  13. The ability of the SFPQ/NONO complex to form varying protein assemblies, in conjunction with the effect of post-translational modifications of SFPQ modulating mRNA binding, suggests key roles affecting mRNP dynamics within the cell.

  14. MALAT1 binds to SFPQ releasing PTBP2 from the SFPQ/PTBP2 complex, the increased SFPQ-detached PTBP2 promotes cell proliferation and migration in colorectal cancer.

  15. The results of this study identify a new physiological role for the PSF-LC3B axis as a potential endogenous modulator of colon cancer treatment.

  16. NEAT1 plays an important role in the innate immune response through the transcriptional regulation of antiviral genes by the stimulus-responsive cooperative action of NEAT1 and SFPQ.

  17. Results suggest that Llme23 can function as an oncogenic RNA and directly associate the polypyrimidine tract-binding (PTB) protein-associated splicing factor (PSF)-binding lncRNA with melanoma.

  18. the effects of PSF on cell proliferation, tumor growth, and cell signaling associated with PPARgamma

  19. Partial knockdown of Annexin A2 and PSF showed decrease in p53 IRES activity and reduced levels of both the p53 isoforms.

  20. PSF and MATR3 are cellular host factors that bind viral RNA and promote Rev activity.

SFPQ Antigen Profile

Protein Summary

FGF-induced protein related to a family of RNA- and DNA-binding proteins

Gene names and symbols associated with SFPQ

  • splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) (Sfpq) antibody
  • splicing factor proline/glutamine-rich (sfpq) antibody
  • splicing factor proline and glutamine rich (SFPQ) antibody
  • splicing factor proline and glutamine rich (Sfpq) antibody
  • 1110004P21Rik antibody
  • 2810416M14Rik antibody
  • 5730453G22Rik antibody
  • 9030402K04Rik antibody
  • AU021830 antibody
  • D4Ertd314e antibody
  • Gm12940 antibody
  • hm:zeh0027 antibody
  • OTTMUSG00000009329 antibody
  • POMP100 antibody
  • PSF antibody
  • REP1 antibody
  • wu:fa11h12 antibody
  • wu:fd10f03 antibody
  • zgc:85935 antibody

Protein level used designations for SFPQ

DNA-binding p52/p100 complex, 100 kDa subunit , PTB-associated splicing factor , PTB-associated-splicing factor , polypyrimidine tract-binding protein-associated-splicing factor , splicing factor, proline- and glutamine-rich , wis , 100 kDa DNA-pairing protein , hPOMp100 , polypyrimidine tract binding protein associated , polypyrimidine tract-binding protein-associated splicing factor , splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) , splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated) , splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) , NonO/p54nrb homolog , gizzard PTB-associated splicing factor

GENE ID SPECIES
71514 Mus musculus
406564 Danio rerio
6421 Homo sapiens
618226 Bos taurus
252855 Rattus norvegicus
395803 Gallus gallus
100688260 Canis lupus familiaris
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