Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) ELISA Kits

The product of SHFM1 has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. Additionally we are shipping SHFM1 Antibodies (44) and SHFM1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SHFM1 7979 P60896
SHFM1 20422 P60897
Anti-Rat SHFM1 SHFM1 680532  
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Top SHFM1 ELISA Kits at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Mouse < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for SHFM1 Interaction Partners

Human Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) interaction partners

  1. Promoter methylation plays a role in modulating DSS1 gene expression. Promoter hypomethylation is a frequent event in melanoma and squamous cell carcinoma and is closely linked to poor prognosis.

  2. DSS1 is a multifunctional and intrinsically disordered protein. (Review)

  3. three phenotypic subregions within the SHFM1 locus link both size and genomic position of the chromosomal aberrations to the clinical variability seen in SHFM1 patients

  4. SHFM1 confers cell cycle progression and resistance to p53 (show TP53 ELISA Kits) stabilizing drugs in gastric cancer cells.

  5. by targeting RPA (show RPA1 ELISA Kits) and mimicking DNA, DSS1 functions with BRCA2 (show BRCA2 ELISA Kits) in a two-component homologous recombination mediator complex in genome maintenance and tumor suppression

  6. Breast cancers with high DSS1 expression have worse prognosis and shorter relapse-free survival times.

  7. Mutation screening of the SHFM1 gene in familial breast/ovarian cancer cases.

  8. DSS1 protein is critically involved in the maintenance of the transformed phenotype in cervical cancer cells, and that it might be a specific, robust and reliable marker for early detection, diagnosis and trea (show TREH ELISA Kits)

  9. DSS1 has a role in homologous recombinational repair in human cells

  10. p63 (show RPE65 ELISA Kits) binds to an enhancer element in the SHFM1 locus and this element controls expression of DLX6 and DLX5 (show DLX5 ELISA Kits) which are important for limb development.

Mouse (Murine) Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) interaction partners

  1. 3.1 angstrom crystal structure of approximately 90-kilodalton BRCA2 domain bound to DSS1, which reveals three oligonucleotide-binding (OB) folds and a helix-turn-helix (HTH) motif

SHFM1 Antigen Profile

Antigen Summary

The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.

Gene names and symbols associated with SHFM1

  • SEM1, 26S proteasome complex subunit (SEM1) antibody
  • SEM1, 26S proteasome complex subunit (Sem1) antibody
  • SEM1, 26S proteasome complex subunit S homeolog (sem1.S) antibody
  • dss1 antibody
  • ecd antibody
  • sem1 antibody
  • shfd1 antibody
  • shfdg1 antibody
  • Shfg antibody
  • shfm1 antibody
  • shfm1.S antibody
  • shsf1 antibody

Protein level used designations for SHFM1

26S proteasome complex subunit DSS1 , deleted in split hand/split foot protein 1 , deleted in split-hand/split-foot 1 , split hand/foot deleted protein 1 , split hand/foot malformation type 1 protein , candidate for split hand/foot malformation type 1 , 26 proteasome complex subunit DSS1 , split hand/foot malformation type 1 protein homolog , split hand/foot malformation (ectrodactyly) type 1 , deleted in split hand/split foot protein 1 homolog , split hand/foot deleted gene 1 , split hand/foot deleted protein 1 homolog , 26S proteasome complex subunit SEM1 , split hand/foot malformation (ectrodactyly) type 1 S homeolog

GENE ID SPECIES
7979 Homo sapiens
608719 Canis lupus familiaris
698349 Macaca mulatta
747549 Pan troglodytes
767981 Bos taurus
772237 Gallus gallus
100038817 Taeniopygia guttata
20422 Mus musculus
680532 Rattus norvegicus
100155621 Sus scrofa
447126 Xenopus laevis
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