anti-Sterile alpha Motif Domain Containing 9 (SAMD9) Antibodies

SAMD9 encodes a sterile alpha motif domain-containing protein. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SAMD9 54809 Q5K651
SAMD9    
SAMD9    
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Top anti-SAMD9 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis in MCF-7 cell line lysates (15ug/lane). SAMD9 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with SAMD9 polyclonal antibody  at 1:250-1:500 dilution. Immunofluorescent staining of human cell line A-431 with SAMD9 polyclonal antibody  at 1-4 ug/mL dilution shows positivity in cytoplasm and vesicles. 100 μL 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL 11 to 16 Days
$658.43
Details
Human Rabbit Cy5 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy7 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy5.5 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit HRP IHC (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy3 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL 14 to 21 Days
$416.90
Details

Top referenced anti-SAMD9 Antibodies

  1. Human Polyclonal SAMD9 Primary Antibody for ICC, IF - ABIN4351962 : Jiang, Opanubi, Coombs: Non-Biased Enrichment Does Not Improve Quantitative Proteomic Delineation of Reovirus T3D-Infected HeLa Cell Protein Alterations. in Frontiers in microbiology 2012 (PubMed)
    Show all 2 Pubmed References

More Antibodies against SAMD9 Interaction Partners

Human Sterile alpha Motif Domain Containing 9 (SAMD9) interaction partners

  1. Acquisition of a somatic nonsense SAMD9 mutation in the cells of the haematopoietic system might revert the cellular growth repression caused by the germline SAMD9 mutations (ie, second-site reversion mutations). Unexpected lack of haematological features in the two patients would be explained by the reversion mutations.

  2. SAMD9 and SAMD9L germline loss-of-function variants exist in 3% of adult myelodysplastic syndromes and are located more in the N terminus relative to pediatric germline loss-of-function variants, which exist more in the C terminus.

  3. SAMD9 expression is (epi-) genetically regulated, and significantly upregulated in PBMCs in RA patients and in activated T cells in vitro. SAMD9 might serve as a T cell activation marker but act as an anti-inflammatory factor.

  4. REVIEW: expert-based recommendations regarding diagnosis, follow-up, and treatment of mutation carriers.

  5. describe the first patient to present with congenital amegakaryocytic thrombocytopenia secondary to MIRAGE syndrome and describe a novel disease-causing SAMD9 allele (c.2462A>T; p.K821M).

  6. Here we describe one patient with a novel de novo mutation p.R824Q in SAMD9 and provide functional evidence of its pathogenicity. We also review a second patient with a previously described p.R1293Q mutation with special attention to dysmorphology and findings that could aid in recognition of the disorder.

  7. In humans, both SAMD9 and SAMD9L are poxvirus restriction factors, although the latter requires interferon induction in many cell types.

  8. findings establish SAMD9/SAMD9L mutations as a new class of germline lesions with variable clinical phenotypes, including familial MDS

  9. Progressive loss of mutated SAMD9 through the development of monosomy 7 (-7), deletions of 7q (7q-), and secondary somatic loss-of-function (nonsense and frameshift) mutations in SAMD9 rescued the growth-restricting effects of mutant SAMD9 proteins in bone marrow and was associated with increased length of survival.

  10. SAMD9 mutation is associated with MIRAGE syndrome.

  11. Replication of the K1L(-)C7L(-) mutant vaccinia virus virus was enabled by multiple siRNAs to SAMD9 or WDR6.

  12. SAMD9 is down-regulated in non-small cell lung cancer. Knockdown of SAMD9 expression increased the invasion, migration and proliferation in H1299 cells in vitro and overexpression of SAMD9 suppressed proliferation and invasion in A549 cells.

  13. When SAMD9 is stimulated due to failure of the viral antagonism during infection, the resulting antiviral granules exhibit properties different from those of the canonical stress granules.

  14. Over-expression of SAMD9 is correlated with the metastasis of esophageal squamous cell carcinoma

  15. M062 also binds and antagonizes cellular SAMD9 in human cells, suggesting that SAMD9 is a novel innate antiviral factor against poxviruses.

  16. SAMD9, an IFN-gamma-responsive protein, interacts with RGL2 to diminish the expression of EGR1, a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation.

  17. SAMD9 could be a key molecule to control cancer cell death by inactivated Sendai virus particle or IFN-beta treatment.

  18. Mutation analysis revealed a homozygous mutation in the SAMD9 gene (K1495E), which was found to segregate with the disease in all families and to interfere with the protein expression.

  19. SAMD9 and SAMD9L are a novel family of genes, which play a role regulating cell proliferation and suppressing the neoplastic phenotype; the human gene exists in rat, but is lost in mouse, due to a mouse specific rearrangement

  20. PIvotal role in calcification and thus implicated in various hereditary diseases such as atherosclerosis, calcinosis and autoimmune diseases.

SAMD9 Antigen Profile

Protein Summary

This gene encodes a sterile alpha motif domain-containing protein. The encoded protein localizes to the cytoplasm and may play a role in regulating cell proliferation and apoptosis. Mutations in this gene are the cause of normophosphatemic familial tumoral calcinosis. Alternate splicing results in multiple transcript variants that encode the same protein.

Gene names and symbols associated with SAMD9

  • sterile alpha motif domain containing 9 (SAMD9) antibody
  • C7orf5 antibody
  • DRIF1 antibody
  • NFTC antibody
  • OEF1 antibody
  • OEF2 antibody

Protein level used designations for SAMD9

sterile alpha motif domain-containing protein 9 , SAM domain-containing protein 9 , expressed in aggressive fibromatosis

GENE ID SPECIES
514205 Bos taurus
54809 Homo sapiens
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