anti-Stress-Induced-phosphoprotein 1 (STIP1) Antibodies

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A\; MIM 140550) and HSP90 (see HSP90AA1\; MIM 140571) in protein folding. Additionally we are shipping Stress-Induced-phosphoprotein 1 Proteins (21) and Stress-Induced-phosphoprotein 1 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
STIP1 10963 P31948
STIP1 20867 Q60864
STIP1 192277 O35814
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Top anti-Stress-Induced-phosphoprotein 1 Antibodies at antibodies-online.com

Showing 10 out of 135 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, IF, IHC (p), ELISA, WB FACS analysis of HeLa cells stained with STIP1 monoclonal antibody clone 2E11 (Green) and non-stained HeLa cells (Black) as negative control. FACS analysis of 293 cells stained with STIP1 monoclonal antibody clone 2E11 (Green) and non-stained 293 cells (Black) as negative control. 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated IF, IHC (p), IP, ELISA, WB Immunoperoxidase of monoclonal antibody to STIP1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 0.3 ug/ml] STIP1 monoclonal antibody (M01), clone 4B6 Western Blot analysis of STIP1 expression in HeLa . 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of STIP1 expression in rat testis extract (lane 1) and MCF-7 whole cell lysates (lane 2). STIP1 at 73KD was detected using rabbit anti- STIP1 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to STIP1 on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to STIP1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11 to 12 Days
$440.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-STIP1 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate STIP1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-STIP1 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate STIP1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Human Muscle 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated IF, IHC, IP, WB Immunofluorescence of monoclonal antibody to STIP1 on HeLa cell (antibody concentration 10 µg/mL). STIP1 monoclonal antibody (M01), clone 4B6 Western Blot analysis of STIP1 expression in HeLa. 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using STIP1, antibody at 1:100 dilution. WB Image Sample(30 μg of whole cell lysate) A:Hep G2, B:MOLT4, 7.5% SDS PAGE antibody diluted at 1:5000 100 μL Log in to see 3 to 4 Days
$358.60
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB STIP1 Antibody (Center) (ABIN1882135) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. STIP1 Antibody (Center) (ABIN1882135) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Mouse Un-conjugated IF, ELISA, WB STIP1 monoclonal antibody (M06), clone 1C6. Western Blot analysis of STIP1 expression in Raw 264.7. STIP1 monoclonal antibody (M06), clone 1C6. Western Blot analysis of STIP1 expression in NIH/3T3. 100 μg Log in to see 11 to 12 Days
$440.00
Details

Top referenced anti-Stress-Induced-phosphoprotein 1 Antibodies

  1. Human Monoclonal STIP1 Primary Antibody for FACS, IF - ABIN524365 : Wang, Chao, Tsai, Chang, Chen, Lee, Chen, Lin, Chang, Wang, Chao, Chang, Chang, Lai, Wang: Stress-induced phosphoprotein 1 as a secreted biomarker for human ovarian cancer promotes cancer cell proliferation. in Molecular & cellular proteomics : MCP 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal STIP1 Primary Antibody for IF, IHC (p) - ABIN564756 : Ho, Kong, Choong, Loh, Toy, Chong, Wong, Wong, Shah, Lim: Novel breast cancer metastasis-associated proteins. in Journal of proteome research 2009 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal STIP1 Primary Antibody for FACS, IHC (p) - ABIN1882135 : Onuoha, Coulstock, Grossmann, Jackson: Structural studies on the co-chaperone Hop and its complexes with Hsp90. in Journal of molecular biology 2008 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal STIP1 Primary Antibody for IF, IHC (p) - ABIN564757 : Footz, Johnson, Dubois, Boivin, Raymond, Walter: Glaucoma-associated WDR36 variants encode functional defects in a yeast model system. in Human molecular genetics 2009 (PubMed)

  5. Human Monoclonal STIP1 Primary Antibody for IF, ELISA - ABIN950133 : Tsai, Tsai, Lin, Chen, Lee, Chao, Wang, Wang, Lai: Secreted stress-induced phosphoprotein 1 activates the ALK2-SMAD signaling pathways and promotes cell proliferation of ovarian cancer cells. in Cell reports 2012 (PubMed)

More Antibodies against Stress-Induced-phosphoprotein 1 Interaction Partners

Mouse (Murine) Stress-Induced-phosphoprotein 1 (STIP1) interaction partners

  1. In conclusion, STIP1 is upregulated in HCC (show FAM126A Antibodies) and associated with poor clinical prognosis. Blocking STIP1 activity suppresses HCC (show FAM126A Antibodies) cell growth, providing the rationale for STIP1 as a potential therapeutic target in HCC (show FAM126A Antibodies).

  2. Domains of STIP1 responsible for regulating PrPC (show PRNP Antibodies)-dependent amyloid-beta oligomer toxicity

  3. Reduced STIP1 levels can contribute to phenotypes related to hyperactivity and attention deficits.

  4. We correlate the expression of STI1 and glioma progression, and suggest that STI1 expression in microglia/macrophages and infiltrating lymphocytes is modulated by the brain tumor microenvironment.

  5. Knockdown of PIAS1 (show PIAS1 Antibodies) in astrocytes impairs the accumulation of nuclear STI1 in response to irradiation. Moreover, a PIAS1 (show PIAS1 Antibodies) mutant lacking the STI1 binding site is unable to increase STI1 nuclear retention.

  6. stress-inducible protein-1 has a role in recruitment of bone marrow derived cells into the ischemic brains

  7. Our findings reveal a previously unrecognized role of the PrP(C (show PRNP Antibodies)) ligand STI1 in protecting neurons in Alzheimer disease and suggest a novel pathway that may help to offset AbetaO-induced toxicity.

  8. Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein (show PRNP Antibodies).

  9. STI1 and laminin-gamma1 promote robust axonogenesis in wild-type dorsal root ganglia neurons; STI1 promotes extracellular calcium influx.

  10. Neuroprotection and neuritogenesis mediated by PrP(C (show PRNP Antibodies))-STI1 engagement are dependent upon the increased protein synthesis mediated by PI3K-mTOR (show FRAP1 Antibodies) signaling.

Human Stress-Induced-phosphoprotein 1 (STIP1) interaction partners

  1. Significant genetic association was identified at the rs2236647 (T/C) SNP in STIP1 and risk of asthma (p < 0.001). The C allele and CC genotype of this SNP were significantly higher in asthmatics compared with controls.

  2. Functional studies showed that STIP1 promoted the growth, colony formation and migration of cancer cells. However, knocking down the expression of STIP1 inhibited the growth, colony formation and migration of cancer cells.

  3. In vitro experiments revealed that STIP1 was capable of binding to the MMP-9 (show MMP9 Antibodies) promoter and enhanced its transcriptional expression

  4. STIP1 modulates the function of the HSP90 (show HSP90 Antibodies)-JAK2 (show JAK2 Antibodies)-STAT3 (show STAT3 Antibodies) complex

  5. Hsp70/Hsp90-organizing protein promoter activity was highest in Hs578T which expressed mutant or inactive p53 (show TP53 Antibodies). HRAS (show HRAS Antibodies) activation of the Hsp70/Hsp90-organizing protein promoter was inhibited by p53 (show TP53 Antibodies) overexpression.

  6. the modulation of HOP-PrP(C (show PRNP Antibodies)) engagement or the decrease of PrP(C (show PRNP Antibodies)) and HOP expression may represent a potential therapeutic intervention in glioblastoma.

  7. In conclusion, STIP1 is upregulated in HCC (show FAM126A Antibodies) and associated with poor clinical prognosis. Blocking STIP1 activity suppresses HCC (show FAM126A Antibodies) cell growth, providing the rationale for STIP1 as a potential therapeutic target in HCC (show FAM126A Antibodies).

  8. Data suggest that calcium signaling plays important role in prevention of protein misfolding; complexes of S100A1 (show S100A1 Antibodies) and STIP1 are key players in this pathway; the stoichiometry of S100A1 (show S100A1 Antibodies)/STIP1 interaction appears to be three S100A1 (show S100A1 Antibodies) dimers plus one STIP1 monomer; each S100A1 (show S100A1 Antibodies)-STIP1-binding interaction is entropically driven. (S100A1 (show S100A1 Antibodies) = S100 calcium binding protein A1 (show S100A1 Antibodies); STIP1 = stress-induced-phosphoprotein 1) [REVIEW]

  9. Results indicte the great potential of STIP1 (stress-induced phosphoprotein 1) as a biomarker and therapeutic target in renal cell carcinoma (show MOK Antibodies) (RCC (show XRCC1 Antibodies)) bone metastasis.

  10. Data suggest that three dimers of S100A1 (S100 calcium binding protein A1 (show S100A1 Antibodies)) associate with one molecule of STIP1 (stress-inducible phosphoprotein 1) in a calcium-dependent manner; individual STIP1 TPR (tetratricopeptide repeat) domains, TPR1, TPR2A and TPR2B, bind a single S100A1 (show S100A1 Antibodies) dimer with significantly different affinities; TPR2B domain possesses highest affinity for S100A1 (show S100A1 Antibodies).

Stress-Induced-phosphoprotein 1 (STIP1) Antigen Profile

Protein Summary

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A\; MIM 140550) and HSP90 (see HSP90AA1\; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005

Gene names and symbols associated with STIP1

  • stress induced phosphoprotein 1 (STIP1) antibody
  • stress-induced phosphoprotein 1 (Stip1) antibody
  • stress induced phosphoprotein 1 L homeolog (stip1.L) antibody
  • Stress-induced-phosphoprotein 1 (GL50803_27310) antibody
  • stress-induced-phosphoprotein 1 (PGTG_06468) antibody
  • stress induced phosphoprotein 1 (stip1) antibody
  • stress induced phosphoprotein 1 S homeolog (stip1.S) antibody
  • stress-induced phosphoprotein 1 (stip1) antibody
  • stress induced phosphoprotein 1 (Stip1) antibody
  • Hop antibody
  • IEF-SSP-3521 antibody
  • MGC53256 antibody
  • MGC76181 antibody
  • MGC82554 antibody
  • p60 antibody
  • Sti1 antibody
  • STI1L antibody
  • stip1 antibody
  • zgc:92133 antibody

Protein level used designations for STIP1

Hsp70/Hsp90-organizing protein , NY-REN-11 antigen , hsc70/Hsp90-organizing protein , renal carcinoma antigen NY-REN-11 , transformation-sensitive protein IEF SSP 3521 , Hsp70/Hsp90 organizing protein , IEF SSP 3521 , mSTI1 , stress-induced-phosphoprotein 1 , stress-inducible protein , STI1 , hop , stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) , Stress-induced-phosphoprotein 1 , Hsc70/Hsp90-organizing protein

GENE ID SPECIES
10963 Homo sapiens
20867 Mus musculus
192277 Rattus norvegicus
379955 Xenopus laevis
451286 Pan troglodytes
474837 Canis lupus familiaris
717926 Macaca mulatta
5697231 Giardia lamblia ATCC 50803
10539523 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100356266 Oryctolagus cuniculus
394990 Xenopus (Silurana) tropicalis
447010 Xenopus laevis
493606 Danio rerio
617109 Bos taurus
100689413 Cricetulus griseus
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