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anti-Stress-Induced-phosphoprotein 1 (STIP1) Antibodies

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. Additionally we are shipping Stress-Induced-phosphoprotein 1 Kits (7) and Stress-Induced-phosphoprotein 1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
STIP1 20867 Q60864
STIP1 192277 O35814
STIP1 10963 P31948
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Top anti-Stress-Induced-phosphoprotein 1 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: STI1 Antibody [NBP1-32145] - (50 ug of whole cell lysate) mouse liver 7.5% SDS PAGE; antibody diluted at 1:1000 Western Blot: STI1 Antibody [NBP1-32145] - Sample(30 ug of whole cell lysate) A:Hep G2 B:MOLT4 7.5% SDS PAGE, antibody diluted at 1:5000. 100 μL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Lung Tissue; Lane2: Human Jurkat Cells; Lane3: Bovine Testis Tissue; Lane4: Bovine Spleen Tissue. Figure. Western Blot; Sample: Recombinant STIP1, Human. 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Mouse Un-conjugated IF, IP, ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Dog Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$727.83
Details
Human Mouse Un-conjugated ELISA, FACS, IHC, IHC (p), WB Human Small Intestine, Muscularis Propria: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$727.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: STI1 Antibody - Staining of human testis shows strong cytoplasmic positivity in basal cells of the seminiferous ducts. Western Blot: STI1 Antibody 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p), WB   100 μL Log in to see 7 to 9 Days
$507.83
Details
Chicken Mouse Un-conjugated IP, WB   50 μg Log in to see 7 to 9 Days
$610.50
Details

STIP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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More Antibodies against Stress-Induced-phosphoprotein 1 Interaction Partners

Mouse (Murine) Stress-Induced-phosphoprotein 1 (STIP1) interaction partners

  1. In conclusion, STIP1 is upregulated in HCC (show FAM126A Antibodies) and associated with poor clinical prognosis. Blocking STIP1 activity suppresses HCC (show FAM126A Antibodies) cell growth, providing the rationale for STIP1 as a potential therapeutic target in HCC (show FAM126A Antibodies).

  2. Domains of STIP1 responsible for regulating PrPC (show PRNP Antibodies)-dependent amyloid-beta oligomer toxicity

  3. Reduced STIP1 levels can contribute to phenotypes related to hyperactivity and attention deficits.

  4. We correlate the expression of STI1 and glioma progression, and suggest that STI1 expression in microglia/macrophages and infiltrating lymphocytes is modulated by the brain tumor microenvironment.

  5. Knockdown of PIAS1 (show PIAS1 Antibodies) in astrocytes impairs the accumulation of nuclear STI1 in response to irradiation. Moreover, a PIAS1 (show PIAS1 Antibodies) mutant lacking the STI1 binding site is unable to increase STI1 nuclear retention.

  6. stress-inducible protein-1 has a role in recruitment of bone marrow derived cells into the ischemic brains

  7. Our findings reveal a previously unrecognized role of the PrP(C (show PRNP Antibodies)) ligand STI1 in protecting neurons in Alzheimer disease and suggest a novel pathway that may help to offset AbetaO-induced toxicity.

  8. Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein (show PRNP Antibodies).

  9. STI1 and laminin-gamma1 promote robust axonogenesis in wild-type dorsal root ganglia neurons; STI1 promotes extracellular calcium influx.

  10. Neuroprotection and neuritogenesis mediated by PrP(C (show PRNP Antibodies))-STI1 engagement are dependent upon the increased protein synthesis mediated by PI3K-mTOR (show FRAP1 Antibodies) signaling.

Human Stress-Induced-phosphoprotein 1 (STIP1) interaction partners

  1. Functional studies showed that STIP1 promoted the growth, colony formation and migration of cancer cells. However, knocking down the expression of STIP1 inhibited the growth, colony formation and migration of cancer cells.

  2. In vitro experiments revealed that STIP1 was capable of binding to the MMP-9 (show MMP9 Antibodies) promoter and enhanced its transcriptional expression

  3. STIP1 modulates the function of the HSP90 (show HSP90 Antibodies)-JAK2 (show JAK2 Antibodies)-STAT3 (show STAT3 Antibodies) complex

  4. Hsp70/Hsp90-organizing protein promoter activity was highest in Hs578T which expressed mutant or inactive p53 (show TP53 Antibodies). HRAS (show HRAS Antibodies) activation of the Hsp70/Hsp90-organizing protein promoter was inhibited by p53 (show TP53 Antibodies) overexpression.

  5. the modulation of HOP-PrP(C (show PRNP Antibodies)) engagement or the decrease of PrP(C (show PRNP Antibodies)) and HOP expression may represent a potential therapeutic intervention in glioblastoma.

  6. In conclusion, STIP1 is upregulated in HCC (show FAM126A Antibodies) and associated with poor clinical prognosis. Blocking STIP1 activity suppresses HCC (show FAM126A Antibodies) cell growth, providing the rationale for STIP1 as a potential therapeutic target in HCC (show FAM126A Antibodies).

  7. Data suggest that calcium signaling plays important role in prevention of protein misfolding; complexes of S100A1 (show S100A1 Antibodies) and STIP1 are key players in this pathway; the stoichiometry of S100A1 (show S100A1 Antibodies)/STIP1 interaction appears to be three S100A1 (show S100A1 Antibodies) dimers plus one STIP1 monomer; each S100A1 (show S100A1 Antibodies)-STIP1-binding interaction is entropically driven. (S100A1 (show S100A1 Antibodies) = S100 calcium binding protein A1 (show S100A1 Antibodies); STIP1 = stress-induced-phosphoprotein 1) [REVIEW]

  8. Results indicte the great potential of STIP1 (stress-induced phosphoprotein 1) as a biomarker and therapeutic target in renal cell carcinoma (show MOK Antibodies) (RCC (show XRCC1 Antibodies)) bone metastasis.

  9. Data suggest that three dimers of S100A1 (S100 calcium binding protein A1 (show S100A1 Antibodies)) associate with one molecule of STIP1 (stress-inducible phosphoprotein 1) in a calcium-dependent manner; individual STIP1 TPR (tetratricopeptide repeat) domains, TPR1, TPR2A and TPR2B, bind a single S100A1 (show S100A1 Antibodies) dimer with significantly different affinities; TPR2B domain possesses highest affinity for S100A1 (show S100A1 Antibodies).

  10. Data confirmed the significant up-regulation of STIP1 in tumorous cholangiocytes relative to normal hepatocytes and non-tumorous cells and show prooved it as a reliable diagnostic biomarker when using immunohistochemistry.

Stress-Induced-phosphoprotein 1 (STIP1) Antigen Profile

Protein Summary

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A\; MIM 140550) and HSP90 (see HSP90AA1\; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005

Gene names and symbols associated with STIP1

  • stress induced phosphoprotein 1 L homeolog (stip1.L) antibody
  • stress induced phosphoprotein 1 (STIP1) antibody
  • Stress-induced-phosphoprotein 1 (GL50803_27310) antibody
  • stress-induced-phosphoprotein 1 (PGTG_06468) antibody
  • stress induced phosphoprotein 1 (stip1) antibody
  • stress induced phosphoprotein 1 S homeolog (stip1.S) antibody
  • stress-induced phosphoprotein 1 (stip1) antibody
  • stress-induced phosphoprotein 1 (Stip1) antibody
  • stress induced phosphoprotein 1 (Stip1) antibody
  • tuftelin interacting protein 11 L homeolog (tfip11.L) antibody
  • HOP antibody
  • IEF-SSP-3521 antibody
  • MGC53256 antibody
  • MGC76181 antibody
  • MGC82554 antibody
  • P60 antibody
  • STI1 antibody
  • STI1L antibody
  • stip antibody
  • stip1 antibody
  • zgc:92133 antibody

Protein level used designations for STIP1

stress-induced-phosphoprotein 1 , stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) , Stress-induced-phosphoprotein 1 , Hsp70/Hsp90 organizing protein , IEF SSP 3521 , hsc70/Hsp90-organizing protein , mSTI1 , stress-inducible protein , STI1 , hop , Hsc70/Hsp90-organizing protein , Hsp70/Hsp90-organizing protein , NY-REN-11 antigen , renal carcinoma antigen NY-REN-11 , transformation-sensitive protein IEF SSP 3521 , STIP-1 , septin and tuftelin-interacting protein 1 , tuftelin-interacting protein 11

GENE ID SPECIES
379955 Xenopus laevis
451286 Pan troglodytes
717926 Macaca mulatta
5697231 Giardia lamblia ATCC 50803
10539523 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100356266 Oryctolagus cuniculus
394990 Xenopus (Silurana) tropicalis
447010 Xenopus laevis
493606 Danio rerio
20867 Mus musculus
192277 Rattus norvegicus
100689413 Cricetulus griseus
10963 Homo sapiens
474837 Canis lupus familiaris
617109 Bos taurus
447466 Xenopus laevis
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