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STIP1 Products

(Stress-Induced-phosphoprotein 1 (STIP1))

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STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A\; MIM 140550) and HSP90 (see HSP90AA1\; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009].

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Featured STIP1 Categories

STIP1 Antibodies

High quality antibodies with extensive validation data.

STIP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

STIP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STIP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IP, IHC (p)
Validations
  • (3)
  • (8)
Cat. No. ABIN564756
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (8)
Cat. No. ABIN564757
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), FACS
Validations
  • (3)
  • (14)
Cat. No. ABIN524365
Quantity 100 μg
Datasheet Datasheet

Recommended STIP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6962705
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959730
Quantity 96 tests
Datasheet Datasheet

Recommended STIP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1321633
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321641
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321643
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our STIP1 products

Krafft, Tschirdewahn, Hess, Harke, Hadaschik, Nyirády, Szendröi, Szücs, Módos, Olah, Székely, Reis, Szarvas: "STIP1 Tissue Expression Is Associated with Survival in Chemotherapy-Treated Bladder Cancer Patients." in: Pathology oncology research : POR, Vol. 26, Issue 2, pp. 1243-1249, (2020) (PubMed).

Carvalho da Fonseca, Wang, Fan, Chen, Zhang, Zhang, Lima, Badie: "Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages." in: Journal of neuroimmunology, Vol. 274, Issue 1-2, pp. 71-7, (2014) (PubMed).

Chao, Lai, Tsai, Hsueh, Hsueh, Lin, Chou, Lin, Chen, Chang, Wang: "Tumor stress-induced phosphoprotein1 (STIP1) as a prognostic biomarker in ovarian cancer." in: PLoS ONE, Vol. 8, Issue 2, pp. e57084, (2013) (PubMed).

Braunschweig, Krakowiak, Duncanson, Boyce, Hansen, Ashwood, Hertz-Picciotto, Pessah, Van de Water: "Autism-specific maternal autoantibodies recognize critical proteins in developing brain." in: Translational psychiatry, Vol. 3, pp. e277, (2013) (PubMed).

Chao, Lee, Hsueh, Lin, Tsai, Chao, Lin, Chou, Chang, Wang: "Immunohistological analysis of stress-induced phosphoprotein 1 in ovarian cancer patients with low serum cancer antigen 125 levels." in: Taiwanese journal of obstetrics & gynecology, Vol. 52, Issue 2, pp. 185-91, (2013) (PubMed).

Tsai, Tsai, Lin, Chen, Lee, Chao, Wang, Wang, Lai: "Secreted stress-induced phosphoprotein 1 activates the ALK2-SMAD signaling pathways and promotes cell proliferation of ovarian cancer cells." in: Cell reports, Vol. 2, Issue 2, pp. 283-93, (2012) (PubMed).

Wang, Chao, Tsai, Chang, Chen, Lee, Chen, Lin, Chang, Wang, Chao, Chang, Chang, Lai, Wang: "Stress-induced phosphoprotein 1 as a secreted biomarker for human ovarian cancer promotes cancer cell proliferation." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 9, pp. 1873-84, (2010) (PubMed).

Ho, Kong, Choong, Loh, Toy, Chong, Wong, Wong, Shah, Lim: "Novel breast cancer metastasis-associated proteins." in: Journal of proteome research, Vol. 8, Issue 2, pp. 583-94, (2009) (PubMed).

Nakamura, Morisawa, Imajoh-Ohmi, Takamura, Fukuda, Toda et al.: "Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis: an increase in lamin A/C associated with heat shock protein 90 in response to ..." in: Experimental gerontology, Vol. 44, Issue 6-7, pp. 375-82, (2009) (PubMed).

Footz, Johnson, Dubois, Boivin, Raymond, Walter: "Glaucoma-associated WDR36 variants encode functional defects in a yeast model system." in: Human molecular genetics, Vol. 18, Issue 7, pp. 1276-87, (2009) (PubMed).

Synonyms and alternative names related to STIP1

stress induced phosphoprotein 1 (STIP1), stress-induced phosphoprotein 1 (Stip1), stress induced phosphoprotein 1 L homeolog (stip1.L), Stress-induced-phosphoprotein 1 (GL50803_27310), stress-induced-phosphoprotein 1 (PGTG_06468), stress induced phosphoprotein 1 (stip1), stress induced phosphoprotein 1 S homeolog (stip1.S), stress-induced phosphoprotein 1 (stip1), stress induced phosphoprotein 1 (Stip1), HOP, Hop, IEF-SSP-3521, MGC53256, MGC76181, MGC82554, P60, p60, STI1, Sti1, STI1L, stip1, zgc:92133

Protein level used designations for STIP1

  • Hsp70/Hsp90-organizing protein
  • NY-REN-11 antigen
  • hsc70/Hsp90-organizing protein
  • renal carcinoma antigen NY-REN-11
  • transformation-sensitive protein IEF SSP 3521
  • Hsp70/Hsp90 organizing protein
  • IEF SSP 3521
  • mSTI1
  • stress-induced-phosphoprotein 1
  • stress-inducible protein
  • STI1
  • hop
  • stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)
  • Stress-induced-phosphoprotein 1
  • Hsc70/Hsp90-organizing protein
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