Surfactant Protein D (SFTPD) ELISA Kits

Contributes to the lung's defense against inhaled microorganisms. Additionally we are shipping Surfactant Protein D Antibodies (178) and Surfactant Protein D Proteins (28) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SFTPD 6441 P35247
SFTPD 25350 P35248
SFTPD 20390 P50404
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Top Surfactant Protein D ELISA Kits at

Showing 10 out of 89 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.233 ng/mL 0.625 ng/mL - 40 ng/mL Typical standard curve SDS-PAGE of Protein Standard from the Kit (Highly purified E. coli-expressed recombinant human SPD). 96 Tests Log in to see 12 to 14 Days
Rat 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
Mouse 10pg/mL 312-20.000 pg/mL Mouse SP-D PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
Pig 0.58 ng/mL 2.35-150 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Cow 0.47 ng/mL 1.88-120 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Rabbit 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
Chicken 46.875 pg/mL 78.125-5000 pg/mL   96 Tests Log in to see 12 to 14 Days
Monkey 1.0 pg/mL 25-500 pg/mL   96 Tests Log in to see 15 to 18 Days
Dog 0.78 ng/mL 3.12-200 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days

Top referenced Surfactant Protein D ELISA Kits

  1. Human SFTPD ELISA Kit for Sandwich ELISA - ABIN414528 : Salman, Akpinar, Yigit, Gormus: Surfactant protein A and D in chronic rhinosinusitis with nasal polyposis and corticosteroid response. in American journal of rhinology & allergy 2012 (PubMed)
    Show all 8 Pubmed References

  2. Human SFTPD ELISA Kit for Sandwich ELISA - ABIN6574247 : Holland, DeRuyter, Doughman: Langerhans cells in organ-cultured corneas. in Archives of ophthalmology (Chicago, Ill. : 1960) 1987 (PubMed)
    Show all 8 Pubmed References

  3. Rat (Rattus) SFTPD ELISA Kit for Sandwich ELISA - ABIN367579 : Güzel, Güzel, Günaydin, Alaçam, Saliş, Sükrü Paksu, Murat, Gacar, Güvenç: The role of iNOS inhibitors on lung injury induced by gastrointestinal decontamination agents aspiration. in Journal of molecular histology 2012 (PubMed)
    Show all 3 Pubmed References

  4. Rat (Rattus) SFTPD ELISA Kit for Sandwich ELISA - ABIN580424 : Kadoya, Lee, Ogami, Oyabu, Nishi, Yamamoto, Todoroki, Morimoto, Tanaka, Myojo: Analysis of pulmonary surfactant in rat lungs after inhalation of nanomaterials: Fullerenes, nickel oxide and multi-walled carbon nanotubes. in Nanotoxicology 2016 (PubMed)
    Show all 2 Pubmed References

  5. Rat (Rattus) SFTPD ELISA Kit for Sandwich ELISA - ABIN416223 : Horie, Fukui, Endoh, Maru, Miyauchi, Shichiri, Fujita, Niki, Hagihara, Yoshida, Morimoto, Iwahashi: Comparison of acute oxidative stress on rat lung induced by nano and fine-scale, soluble and insoluble metal oxide particles: NiO and TiO2. in Inhalation toxicology 2012 (PubMed)
    Show all 2 Pubmed References

  6. Human SFTPD ELISA Kit for Sandwich ELISA - ABIN1000111 : Ju, Liu, Chen: Serum surfactant protein D: biomarker of chronic obstructive pulmonary disease. in Disease markers 2012 (PubMed)
    Show all 2 Pubmed References

  7. Mouse (Murine) SFTPD ELISA Kit for Sandwich ELISA - ABIN415784 : Yu, Islam, Sikora, Dworski, Gurka, López-Vásquez, Liu, Kuebler, Levade, Zhang, Medin: Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency. in American journal of physiology. Lung cellular and molecular physiology 2019 (PubMed)

More ELISA Kits for Surfactant Protein D Interaction Partners

Human Surfactant Protein D (SFTPD) interaction partners

  1. Pro-SFTPB levels were significantly higher among people with HIV (adjusted geometric mean, 21.4 vs 18.1 ng/mL; P = .03), and were higher with lower CD4 counts (P trend = .001), higher HIV RNA (P trend = .05), and without highly active antiretroviral therapy (P = .03). These associations were not observed for SFTPD.

  2. Evaluation of surfactant proteins A, B, C, and D in articular cartilage, synovial membrane and synovial fluid of healthy as well as patients with osteoarthritis and rheumatoid arthritis.

  3. these findings indicate that the membrane-type surfactant protein D serve as an effective therapeutic strategy for inhibiting macrophage-mediated xenograft rejection in xenotransplantation

  4. Assays that can separate SP-D proteolytic breakdown products or modified forms from naturally occurring SP-D trimers may result in optimal disease markers for pulmonary inflammatory diseases

  5. TGF beta markedly decreased expression of SP-A, SP-B, SP-C, fatty acid synthase, and the phospholipid transporter ABCA3. However, TGF beta increased protein levels of SP-D with little change in mRNA levels.

  6. the SPA and SPD levels in EBC were correlated with lung function, which contributed to COPD diagnosis.

  7. Studied predictive value of surfactant protein D (SP-D) in lung cancer patients with interstitial lung disease induced by anticancer agents (ILD-AA). Results suggest that SP-D level change was a risk factor for mortality in patients with ILD-AA, and that SP-D might be a predictive prognostic biomarker of ILD-AA.

  8. SP-D also delays FasL-induced death of primary human T cells. SP-D delaying the progression of the extrinsic pathway of apoptosis could have important implications in regulating immune cell homeostasis at mucosal surfaces

  9. findings suggest that these pulmonary markers could be useful to assess CAP severity and, especially YKL-40 and CCL18 by helping predict CAP caused by atypical pathogens

  10. Trimeric SP-D wildtype recognized larger LPS inner core oligosaccharides with slightly enhanced affinity than smaller compounds suggesting the involvement of stabilizing secondary interactions.

  11. rs2819096 in the surfactant protein D (SFTPD) gene was associated with a higher risk of COPD GOLD III + IV.

  12. SP-D increases the formation of nuclear and membrane blebs. Inhibition of caspase-8 confirms the effect of SP-D is unique to the caspase-8 pathway.

  13. Findings indicate serum pulmonary surfactant protein D (SP-D, SFTPD) level as a potential marker to estimate the efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKIs).

  14. Patients with SP-D 11Thr/Thr genotype were more susceptible to acute kidney injury (AKI). Compared with healthy controls, serum SP-D levels at day 1, 3 and 7 were significantly elevated in AKI patients.

  15. This review intends to provide a current overview of the genetics, structure and extra-pulmonary functions of the surfactant collectin proteins.

  16. Meta-analysis found that serum SP-A/D detection might be useful for differential diagnosis and prediction of survival in patients with idiopathic pulmonary fibrosis.

  17. The findings suggest that SP-D inhibits LPS-stimulated production of interleukin-12p40 via the SIRPalpha/ROCK/ERK signaling pathway.

  18. Efficient lipopolysaccharide recognition by SP-D requires multiple binding interactions utilizing the three major ligand-binding determinants in the SP-D binding pocket, with Ca-dependent binding of inner-core heptose accompanied by interaction of anhydro-Kdo (4,7-anhydro-3-deoxy-d-manno-oct-2-ulosonic acid) with Arg343 and Asp325.

  19. SP-D levels in bronchoalveolar lavage samples were significantly lower in severe asthma compared with healthy controls and mild asthma. Serum SP-D was significantly increased in severe asthma compared with healthy controls and mild asthma.

  20. SP-A (+186A/G) and SP-B (1580C/T) polymorphisms are strongly associated with the risk of respiratory distress syndrome (RDS) in preterm infants. Notably, reduced serum SP-A levels were correlated with a high risk of RDS and may serve as novel biomarkers for RDS detection and monitoring.

Cow (Bovine) Surfactant Protein D (SFTPD) interaction partners

  1. Elevation of SP-D is found in bronchoalveolar lavage fluid from inoculated lobes of calves infected with bovine adenovirus type 3.

  2. The bSP-D gene has 9 exons spanning about 10.5 kb on chromosome 28 at position q1.8. The 5'-upstream sequence has cis-regulatory elements. It has 2 polymorphisms in the carbohydrate recognition domain (242 Glu/Val & 268 Ala/Gly).

Pig (Porcine) Surfactant Protein D (SFTPD) interaction partners

  1. The authors demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D.

  2. Data show that interactions of surfactant protein D (pSP-D) with influenza A virus mediated by the N-linked carbohydrate moiety in pSP-D depend on the terminal sialic acids present on this moiety.

  3. The presence of SP-D in endothelial cells which is NO-, PI(3)K/Akt- and Erk-dependent is demonstrated. It suggests a protective role of SP-D in these cells.

  4. The importance of SP-D in innate immunity is underlined by its expression at the potential ports of entry of pathogens: lung, tongue, intestinal tract, thymus, skin, gall bladder, lacrimal gland, esophagus, stomach, kidney, liver, prostate and spleen.

Mouse (Murine) Surfactant Protein D (SFTPD) interaction partners

  1. SP-D binds to melanin present on the dormant A. fumigatus conidial surface, facilitates conidial phagocytosis, and stimulates the host immune response.

  2. Loss of Sftpd do not result in retinal degeneration.

  3. Colitis caused a notable increase in Sftpd gene expression in the gallbladder, but not in the lung, via the activity of glucocorticoids produced in the liver.

  4. SP-D deficiency reduces atherosclerosis in ApoE-knockout mice by decreasing the accumulation and proliferation of macrophages and by reducing IL-6 levels systemically.

  5. The data provide evidence SP-A and SP-D attenuate S. aureus pneumonia severity resulting in decreased intestinal mucosal injury, apoptosis, and inflammation.

  6. In triple KO mice, the HO-induced lung injury was associated with decreased surfactant protein (SP) A and SPC but not SPB and SPD expression.

  7. Our study provides comprehensive information regarding spatial and temporal expression of collectins (SP-A, SP-D and MBL-A) and their cellular sources in murine testis. Positive regulation by testosterone and alteration in their level upon LPS challenge are clues relevant to suggest their involvement in testicular immune privilege.

  8. Our data may promote further studies on the morphological development of the aging lung and the role of SP-D in this process.

  9. The experimentally induced alterations were more severe in the SP-D(-/-) than in the WT mice, particularly with respect to the surfactant-storing lamellar bodies which were sometimes extremely enlarged in SP-D(-/-) mice.

  10. these results demonstrate SP-D plays protective roles by inhibiting apoptosis and modulating NF-kappaB-mediated inflammation in CLP-induced acute pancreatic injury .

  11. SP-A/D double knock-out mice showed increased susceptibility to urinary tract infection

  12. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  13. The presence of SP-A and SP-D in the murine decidua is likely to play a protective role against intrauterine infection during pregnancy.

  14. our results demonstrate that SFTPD deficiency affects female fertility, highlighting roles for SFTPD in ovarian and uterine physiology

  15. the collectin Surfactant Protein D is an essential component of host innate immunity to helminths

  16. SP-D protects the ocular surface from S. aureus infection.

  17. Estrogen positively regulates expression of SP-D in the mouse uterus. Progesterone, along with estrogen synergizes SP-D expression, however, when administered alone results in negative regulation.

  18. NOS2 mediates remodeling of septal walls, resulting in deposition of interstitial tissue in Sftpd(-/-).

  19. Suggest a protective role for SP-D in the pathogenesis of sub-epithelial fibrosis in a mouse model of allergic inflammation through regulation of eosinophil-derived TGF-beta1.

  20. Data indicate that although iNOS is involved in radiation-induced injury and altered SP-D structure, in the absence of SP-D, it functions to promote proinflammatory signaling.

Horse (Equine) Surfactant Protein D (SFTPD) interaction partners

  1. Surfactant protein D and haptoglobin serum concentrations could be a diagnostic aid for equine inflammatory airway disease.

  2. The levels of surfactant protein D and serum amyloid A protein in normal horses and those with bacterial pneumonia are reported.

Surfactant Protein D (SFTPD) Antigen Profile

Antigen Summary

Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Gene names and symbols associated with Surfactant Protein D (SFTPD) ELISA Kits

  • surfactant protein D (SFTPD) antibody
  • surfactant protein D (Sftpd) antibody
  • surfactant protein D (SP-D) antibody
  • surfactant associated protein D (Sftpd) antibody
  • AI573415 antibody
  • COLEC7 antibody
  • PSP-D antibody
  • Sftp4 antibody
  • SP-D antibody
  • SPD antibody

Protein level used designations for Surfactant Protein D (SFTPD) ELISA Kits

collectin 7 , collectin-7 , lung surfactant protein D , pulmonary surfactant apoprotein , pulmonary surfactant-associated protein D , surfactant, pulmonary-associated protein D , surfactant-associated protein, pulmonary 4 , CP4 , PSP-D , pulmonary surfactant protein D , surfactant associated protein D , surfactant protein D , carbohydrate recognition domain , SP-D , LOW QUALITY PROTEIN: pulmonary surfactant-associated protein D

6441 Homo sapiens
25350 Rattus norvegicus
282072 Bos taurus
397198 Sus scrofa
443191 Ovis aries
489066 Canis lupus familiaris
678657 Macaca mulatta
20390 Mus musculus
100728956 Cavia porcellus
102119038 Macaca fascicularis
100357777 Oryctolagus cuniculus
100066341 Equus caballus
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