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SMNDC1 is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy.
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Human Polyclonal SMNDC1 Primary Antibody for IP, WB - ABIN4354835
Giri, Shameer, Zimmermann, Saha, Chakraborty, Sharma, Arvizo, Madden, Mccormick, Kocher, Bhattacharya, Mukherjee: Understanding protein-nanoparticle interaction: a new gateway to disease therapeutics. in Bioconjugate chemistry 2014
The results show that SMNDC1 mRNA 5'-UTR (show UTS2R Antibodies) forms an intramolecular, parallel G quadruplex structure comprised of three G quartet planes, which is bound specifically by FMRP (show FMR1 Antibodies) both in vitro and in mouse brain lysates.
The binding specificity and affinity of the Tudor domains of TDRD3 (show TDRD3 Antibodies), SMN (show STMN1 Antibodies) and SPF30 proteins were characterized quantitatively.
The structures of SMN (show STMN1 Antibodies) and SPF30 Tudor domains bound to symmetric and asymmetric dimethylated arginine (DMA (show HLA-DMA Antibodies)) are presented.
U2AF35 and hPrp3 interactions with SPF30 can occur simultaneously, thereby potentially linking 3' splice site recognition with tri-small nuclear ribonucleoprotein addition
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Survival motor neuron domain-containing protein 1
, survival of motor neuron-related-splicing factor 30
, survival motor neuron domain containing 1
, 30 kDa splicing factor SMNrp
, SMN-related protein
, splicing factor 30, survival of motor neuron-related
, survival motor neuron domain-containing protein 1
, tudor domain containing 16C