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binds and recruits synaptojanin 2A to mitochondria\; facilitates synaptojanin 2A mediated inositol phosphate modification activity that may regulate intracellular distribution of mitochondria [RGD, Feb 2006].. Additionally we are shipping Synaptojanin 2 Binding Protein Antibodies (15) and many more products for this protein.
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Data found that SYNJ2BP was decreased in hepatocellular carcinoma (HCC (show FAM126A Proteins)) tissues and cell lines and provide evidence that SYNJ2BP may act as a tumor suppressor during HCC (show FAM126A Proteins) development activating DLL4 (show DLL4 Proteins) pathway.
Ubiquilins are a family of chaperones for cytosolically exposed transmembrane domains and use ubiquitin to triage clients, like Omp25, for degradation via coordinated intra- and intermolecular interactions.
Synaptojanin-2 binding protein stabilizes the Notch (show NOTCH1 Proteins) ligands DLL1 (show DLL1 Proteins) and DLL4 (show DLL4 Proteins) and inhibits sprouting angiogenesis.
These results suggest that ARIP2 is a putative growth-promoting factor involved in breast tumorigenesis and tumor development.
Overexpression of ARIP2 enhances endocytosis of ActRIIAs; data indicate that ARIP2 is a novel factor regulating cell surface ActRIIA expression and activin function.
ARIP2 expression can be influenced by various factors. ARIP2 may participate in the negative feedback regulation of signal transduction in the late stage by affecting the expression of activin type 2 receptor.
The findings suggest that ARIP2 is widely distributed in various tissues and may be a negative regulator of activin action in pituitary cells.
binds and recruits synaptojanin 2A to mitochondria\; facilitates synaptojanin 2A mediated inositol phosphate modification activity that may regulate intracellular distribution of mitochondria
activin receptor interacting protein 2
, activin receptor-interacting protein 2
, activin receptor-interacting protein 2a
, activin receptor-interacting protein 4
, mitochondrial outer membrane protein 25
, outer membrane protein 25
, synaptojanin-2-binding protein
, activin receptor interacting protein 5
, outer membrane protein
, synaptojanin 2 binding protein