TAPBP Proteins
TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane.
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TAP Binding Protein (Tapasin) (TAPBP) (AA 24-465) protein (rho-1D4 tag) Protein
TAP Binding Protein (Tapasin) (TAPBP) (AA 24-416) protein (His tag) Protein
TAP Binding Protein (Tapasin) (TAPBP) (AA 21-414) protein (His tag) Protein
TAP Binding Protein (Tapasin) (TAPBP) (AA 21-448) protein (rho-1D4 tag) Protein
TAP Binding Protein (Tapasin) (TAPBP) (AA 197-300) protein (GST tag) Protein
TAP Binding Protein (Tapasin) (TAPBP) (AA 1-414) protein (His tag) Protein
TAP Binding Protein (Tapasin) (TAPBP) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
TAPBP Protein Profile
Protein Summary
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Gene names and symbols associated with TAPBP
- TAP binding protein (tapasin), tandem duplicate 1 (tapbp.1) antibody
- TAP binding protein (tapbp) antibody
- TAP binding protein (TAPBP) antibody
- TAP binding protein (Tapbp) antibody
- D17Wsu91e antibody
- mhc1uda antibody
- mhc1ufa antibody
- NGS17 antibody
- SI:dZ179B20.1 antibody
- SI:dZ179B20.3 antibody
- SI:dZ179B20.7 antibody
- TAPA antibody
- TAPBP antibody
- TPN antibody
- TPSN antibody
- zgc:109814 antibody
Protein level used designations for TAPBP
tapasin , TAP binding protein , TAP-associated protein , TAP-binding protein , TPSN , NGS-17 , TPN
| GENE ID | SPECIES |
|---|---|
| 30163 | Danio rerio |
| 100136493 | Salmo salar |
| 100170652 | Ovis aries |
| 21356 | Mus musculus |
| 6892 | Homo sapiens |
| 504335 | Bos taurus |
| 25217 | Rattus norvegicus |
| 417048 | Gallus gallus |
| 481740 | Canis lupus familiaris |
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