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TAPBP Protein (His tag)

TAPBP Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317188
  • Target See all TAPBP Proteins
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    Human
    Source
    • 4
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TAPBP protein is labelled with His tag.
    Purpose
    Recombinant Human TAPBP/ Tapasin Protein (His Tag)
    Sequence
    Met 1-Val414
    Characteristics
    A DNA sequence encoding the human TAPBP (AAH80574.1) (Met1-Val414) was expressed with a polyhistidine tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product TAPBP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    Alternative Name
    TAPBP/ Tapasin (TAPBP Products)
    Synonyms
    SI:dZ179B20.1 Protein, SI:dZ179B20.3 Protein, SI:dZ179B20.7 Protein, mhc1uda Protein, mhc1ufa Protein, tpsn Protein, zgc:109814 Protein, tapbp Protein, TAPBP Protein, D17Wsu91e Protein, TPN Protein, NGS17 Protein, TAPA Protein, TPSN Protein, TAP binding protein (tapasin), tandem duplicate 1 Protein, TAP binding protein Protein, tapbp.1 Protein, tapbp Protein, TAPBP Protein, Tapbp Protein
    Background

    Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. 

    Synonym: NGS17,TAPA,TPN,TPSN

    Molecular Weight
    43.5 kDa
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