TAPBP Protein (His tag)
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- Target See all TAPBP Proteins
- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TAPBP protein is labelled with His tag.
- Purpose
- Recombinant Human TAPBP/ Tapasin Protein (His Tag)
- Sequence
- Met 1-Val414
- Characteristics
- A DNA sequence encoding the human TAPBP (AAH80574.1) (Met1-Val414) was expressed with a polyhistidine tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product TAPBP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
- Alternative Name
- TAPBP/ Tapasin (TAPBP Products)
- Synonyms
- SI:dZ179B20.1 Protein, SI:dZ179B20.3 Protein, SI:dZ179B20.7 Protein, mhc1uda Protein, mhc1ufa Protein, tpsn Protein, zgc:109814 Protein, tapbp Protein, TAPBP Protein, D17Wsu91e Protein, TPN Protein, NGS17 Protein, TAPA Protein, TPSN Protein, TAP binding protein (tapasin), tandem duplicate 1 Protein, TAP binding protein Protein, tapbp.1 Protein, tapbp Protein, TAPBP Protein, Tapbp Protein
- Background
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Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Synonym: NGS17,TAPA,TPN,TPSN
- Molecular Weight
- 43.5 kDa
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