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Component of the THO subcomplex of the TREX complex. Additionally we are shipping THO Complex 7 Homolog (Drosophila) Proteins (9) and and many more products for this protein.
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Human Polyclonal THOC7 Primary Antibody for FACS, WB - ABIN1881883
El Bounkari, Guria, Klebba-Faerber, Claussen, Pieler, Griffiths, Whetton, Koch, Tamura: Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP). in FEBS letters 2008
Show all 4 Pubmed References
THOC7 (50-137, amino acid numbers) binds to the N-terminal portion (1-199) of FMIP directly.
These results imply that murine leukemia virus requires UAP56, THOC5 and THOC7, in addition to NXF1, for nuclear export of viral transcripts.
Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex (By similarity).
THO complex subunit 7 homolog
, NIF3L1-binding protein 1
, Ngg1 interacting factor 3 like 1 binding protein 1
, functional spliceosome-associated protein 24
, ngg1-interacting factor 3-like protein 1-binding protein 1