TIMP Metallopeptidase Inhibitor 1 (TIMP1) ELISA Kits

TIMP1 belongs to the TIMP gene family. Additionally we are shipping TIMP1 Antibodies (305) and TIMP1 Proteins (58) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TIMP1 7076 P01033
TIMP1 116510 P30120
TIMP1 21857 P12032
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Top TIMP1 ELISA Kits at antibodies-online.com

Showing 10 out of 140 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.434 ng/mL 0.39-25 ng/mL 96 Tests Log in to see 13 to 16 Days
Mouse 10pg/mL 31.2-2000 pg/mL Mouse TIMP-1 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
Rat < 4 pg/mL 4-3000 pg/mL 96 Tests Log in to see 2 to 3 Days
Dog 13.2 pg/mL 31.2 pg/mL - 2000 pg/mL 96 Tests Log in to see 13 to 16 Days
Rabbit 24.5 pg/mL 62.5 pg/mL - 4000 pg/mL 96 Tests Log in to see 13 to 16 Days
Pig 0.51 ng/mL 1.25 ng/mL - 80 ng/mL 96 Tests Log in to see 13 to 16 Days
Horse 0.241 ng/mL 0.62 ng/mL - 40 ng/mL 96 Tests Log in to see 13 to 16 Days
Pig 1.95 ng/mL 7.8-500 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
Cow 47 pg/mL 47-3000 pg/mL   96 Tests Log in to see 15 to 18 Days
Sheep 0.08 ng/mL 0.312-20 ng/mL   96 Tests Log in to see 15 to 18 Days

Top referenced TIMP1 ELISA Kits

  1. Human TIMP1 ELISA Kit for Sandwich ELISA - ABIN625098 : Fernández-Yunquera, Ripoll, Bañares, Puerto, Rincón, Yepes, Catalina, Salcedo: Everolimus immunosuppression reduces the serum expression of fibrosis markers in liver transplant recipients. in World journal of transplantation 2014 (PubMed)
    Show all 41 Pubmed References

  2. Human TIMP1 ELISA Kit for Sandwich ELISA - ABIN411358 : Kim, Lee, Choi, Yoo, Yang: Implication of MMP-9 and urokinase plasminogen activator (uPA) in the activation of pro-matrix metalloproteinase (MMP)-13. in Rheumatology international 2012 (PubMed)
    Show all 12 Pubmed References

  3. Mouse (Murine) TIMP1 ELISA Kit for Sandwich ELISA - ABIN625179 : Raghu, Nalla, Gondi, Gujrati, Dinh, Rao: uPA and uPAR shRNA inhibit angiogenesis via enhanced secretion of SVEGFR1 independent of GM-CSF but dependent on TIMP-1 in endothelial and glioblastoma cells. in Molecular oncology 2012 (PubMed)
    Show all 9 Pubmed References

  4. Rat (Rattus) TIMP1 ELISA Kit for Sandwich ELISA - ABIN625215 : Hayakawa, Yamashita, Tanzawa, Uchijima, Iwata: Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum. in FEBS letters 1992 (PubMed)
    Show all 10 Pubmed References

  5. Mouse (Murine) TIMP1 ELISA Kit for Sandwich ELISA - ABIN424239 : Lenglet, Montecucco, Mach, Schaller, Gasche, Copin: Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke. in Thrombosis and haemostasis 2014 (PubMed)
    Show all 6 Pubmed References

  6. Rat (Rattus) TIMP1 ELISA Kit for Sandwich ELISA - ABIN625214 : Clark, Powell, Wright, Cawston: Polyclonal and monoclonal antibodies against human tissue inhibitor of metalloproteinases (TIMP) and the design of an enzyme-linked immunosorbent assay to measure TIMP. in Matrix (Stuttgart, Germany) 1991 (PubMed)
    Show all 7 Pubmed References

  7. Mouse (Murine) TIMP1 ELISA Kit for Sandwich ELISA - ABIN2859278 : Cavdar, Ozbal, Celik, Ergur, Guneli, Ural, Camsari, Guner: The effects of alpha-lipoic acid on MMP-2 and MMP-9 activities in a rat renal ischemia and re-perfusion model. in Biotechnic & histochemistry : official publication of the Biological Stain Commission 2014 (PubMed)
    Show all 6 Pubmed References

  8. Rat (Rattus) TIMP1 ELISA Kit for Sandwich ELISA - ABIN411380 : Scuteri, Ravasi, Pasini, Bossi, Tredici: Mesenchymal stem cells support dorsal root ganglion neurons survival by inhibiting the metalloproteinase pathway. in Neuroscience 2010 (PubMed)
    Show all 8 Pubmed References

  9. Human TIMP1 ELISA Kit for Sandwich ELISA - ABIN415058 : Mern, Fontana, Beierfuß, Thomé, Hegewald et al.: A combinatorial relative mass value evaluation of endogenous bioactive proteins in three-dimensional cultured nucleus pulposus cells of herniated intervertebral discs: identification of potential ... in PLoS ONE 2013 (PubMed)
    Show all 4 Pubmed References

  10. Rat (Rattus) TIMP1 ELISA Kit for Sandwich ELISA - ABIN416390 : Michalski, Pelz, Weise, Kacza, Boltze, Grosche, Kamprad, Schneider, Hobohm, Härtig: Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke. in Experimental & translational stroke medicine 2011 (PubMed)
    Show all 4 Pubmed References

More ELISA Kits for TIMP1 Interaction Partners

Human TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. C-type natriuretic peptide (CNP (show NPPC ELISA Kits))administration significantly decreased the secretion and expression of MMP-2 (show MMP2 ELISA Kits) and MMP-9 (show MMP9 ELISA Kits) in the cultured mesangial cells ; (2) the secretion and expression of TIMP-1 progressively elevated after treatment with CNP (show CNP ELISA Kits) for 24 and 48 h, whereas declined at later time point; (3) CNP (show CNP ELISA Kits) expression was negatively correlated with MMP-2 (show MMP2 ELISA Kits) and MMP-9 (show MMP9 ELISA Kits) expression.

  2. The results of this study demonstrate that the gene expression of MMP9 (show MMP9 ELISA Kits), MMP12 (show MMP12 ELISA Kits), TIMP1 and TIMP2 (show TIMP2 ELISA Kits) was influenced by the addition of TGF-beta1 (show TGFB1 ELISA Kits). These results may be translated to chronic venous insufficiency framework and suggest involvement of TGF-beta1 (show TGFB1 ELISA Kits) in the vein wall pathology.

  3. TIMP-1 modulates leukemic blasts survival, migration and function via CD63 (show CD63 ELISA Kits)/PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits)/p21 (show CDKN1A ELISA Kits) signaling. As a "bad actor" in a "bad soil", TIMP-1 is a potential novel therapeutic target in leukemic bone marrow microenvironment.

  4. CD82 (show CD82 ELISA Kits) is a component of the promiscuous TIMP-1 interacting protein complex on cell surface of human pancreatic adenocarcinoma cells. CD82 (show CD82 ELISA Kits) directly binds to TIMP-1 N-terminal region through its large extracellular loop and co-localizes with TIMP-1.

  5. these results show here that EGFR signaling induces TIMP-1 expression in colorectal cancer cells, and that TIMP-1 promotes a more aggressive behavior, specifically in KRAS mutated cells

  6. Our results provided evidence that polymorphisms in TIMP1, DLX1 and DLX2 genes may be associated with DF phenotypes.

  7. The plasma levels of interleukin (IL)-1beta, tumor necrosis factor (TNF)-alpha, tissue inhibitor of metalloproteinases (TIMP)-1 are increased in myelofibrosis (MF) patients.

  8. The present study suggests that scoring of TIMP-1 immunoreactivity is a better choice than measuring of TIMP-1 plasma levels.

  9. Results show that TIMP1 expression is significantly upregulated in human colon cancer. Its suppression decreases proliferation, and metastasis but increases apoptosis by inducing TIMP1 specific regulated FAK (show PTK2 ELISA Kits)-PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) and MAPK (show MAPK1 ELISA Kits) pathway. These results suggest that TIMP1 may play an important role in promoting tumorigenesis and metastasis of human colon cancer.

  10. cancer associated fibroblasts (CAFs) promoted hepatocellular cancer (HCC) growth via IL-6/STAT3/AKT pathway and TIMP-1 over-expression driven by IL-6/STAT3 pathway in HCC cells brought in more CAFs through activating liver fibroblasts.

Cow (Bovine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Decreased MMP-9 (show MMP9 ELISA Kits) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (show EGF ELISA Kits) on MMP-9 (show MMP9 ELISA Kits) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha, and hepatocyte growth factor (show HGF ELISA Kits) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (show TIMP2 ELISA Kits) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (show TIMP2 ELISA Kits) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (show TIMP2 ELISA Kits) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Pig (Porcine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Results provide evidence for the utility of MMP9 (show MMP9 ELISA Kits) and TIMP1 as markers of age- and lactocrine-sensitive porcine female reproductive tract development.

  2. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (show MMP9 ELISA Kits), TIMP1, and NGAL (show LCN2 ELISA Kits) (also MMP2 (show MMP2 ELISA Kits) in 220 kDa complex) without proteolytic activity.

  3. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (show VEGFA ELISA Kits), pro-MMP-9 (show MMP9 ELISA Kits), MMP-2 (show MMP2 ELISA Kits), VEGFR-1 (show FLT1 ELISA Kits), VEGFR-2 (show KDR ELISA Kits), and TIMP-1, which may contribute to the development of venous stenosis.

  4. Results indicate that leukemia inhibitory factor (LIF (show LIF ELISA Kits)) and Oncostatin M (show OSM ELISA Kits) increase the expression of MMP-1 (show MMP1 ELISA Kits), MMP-3 (show MMP3 ELISA Kits), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF ELISA Kits) antagonist MH35-BD.

Rabbit TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (show MMP2 ELISA Kits), MMP-9 (show MMP9 ELISA Kits) and TIMP-1 in rabbits with acute paraquat poisoning.

Mouse (Murine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. These results show that MMP-9 (show MMP9 ELISA Kits)/TIMP-1 system disturbance and changes of histological structure in uteri tissue are involved in fluoride-induced reproductive dysfunctions.

  2. Tissue inhibitor of matrix metalloproteinases 1 (TIMP1) inhibition resensitized tumors to gemcitabine and radiotherapy.

  3. proteomic analysis of the mesenchymal stem cells secretome identified the TIMP-1 as a potential effector molecule responsible for the anti-angiogenic properties of MSC (show MSC ELISA Kits)

  4. TIMP1 signaling via CD63 (show CD63 ELISA Kits) leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  5. This study highlights a previously undescribed integral role for TIMP1 in both vascular network maturation and adaptations to ischemia or alterations in flow.

  6. TIMP-1 was identified as a selectively upregulated component secreted from immature astrocytes from human pluripotent stem cells.

  7. demonstrate that TIMP-2 (show TIMP2 ELISA Kits) plays a greater protective role than TIMP-1 during the pathogenesis of atherosclerosis

  8. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63 (show CD63 ELISA Kits).

  9. TIMP-1 is a ligand of LRP-1 (show LRP1 ELISA Kits) and we highlight a new example of its MMP-independent, cytokine-like functions.

  10. RAB37 (show RAB37 ELISA Kits) regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 (show MMP9 ELISA Kits) migration axis in vitro and in vivo and to suppress tumor metastasis.

TIMP1 Antigen Profile

Antigen Summary

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Gene names and symbols associated with TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1) antibody
  • TIMP metallopeptidase inhibitor 1 (Timp1) antibody
  • tissue inhibitor of metalloproteinase 1 (Timp1) antibody
  • Clgi antibody
  • DKFZp468A0912 antibody
  • EPA antibody
  • EPO antibody
  • HCI antibody
  • Timp antibody
  • TIMP-1 antibody
  • TIMP1 antibody

Protein level used designations for TIMP1

tissue inhibitor of matrix metalloproteinase-1 , TIMP metallopeptidase inhibitor 1 , Metalloproteinase inhibitor 1 , TIMP-1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinases 1 , EG-1 , embryogenin-1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metallopeptidase 1 , tissue inhibitor of metalloproteinase 1 , metalloproteinase tissue inhibitor , metalloproteinase tissue inhibitor 1 , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

574348 Macaca mulatta
100172253 Pongo abelii
7076 Homo sapiens
282092 Bos taurus
116510 Rattus norvegicus
101686851 Mustela putorius furo
443331 Ovis aries
396862 Sus scrofa
403816 Canis lupus familiaris
100009047 Oryctolagus cuniculus
21857 Mus musculus
100034220 Equus caballus
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