TYRO Protein tyrosine Kinase Binding Protein (TYROBP) ELISA Kits

Antigen Summary

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with TYROBP

• TYRO protein tyrosine kinase binding protein (TYROBP) antibody
• TYRO protein tyrosine kinase binding protein (tyrobp) antibody
• Tyro protein tyrosine kinase binding protein (Tyrobp) antibody
• TYRO protein tyrosine kinase binding protein (Tyrobp) antibody

• dap12 antibody
• KARAP antibody
• Ly83 antibody
• PLOSL antibody
• TYROBP antibody
• Show all synonym aliases
• tyrpbp antibody

Protein level used designations for TYROBP

TYRO protein tyrosine kinase-binding protein , TYRO protein tyrosine kinase binding protein , DAP12 protein , dap12 , DAP12 , DNAX-activation protein 12 , killer cell activating receptor-associated protein , KAR-associated protein , killer activating receptor associated protein , killer-activating receptor-associated protein , killer cell activating receptor associated protein , immunoreceptor DAP12 , tyrosine kinase binding protein