anti-Thrombomodulin (THBD) Antibodies

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin.

list all antibodies Gene Name GeneID UniProt
Anti-Human THBD THBD 7056 P07204
Anti-Mouse THBD THBD 21824 P15306
Anti-Rat THBD THBD 83580  
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Top anti-Thrombomodulin Antibodies at antibodies-online.com

Showing 10 out of 368 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of CD141 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rat PE FACS Detection of Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse Thrombomodulin/BDCA-3 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$334.65
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: THP-1 7.5% SDS PAGE antibody diluted at 1:500 IHC-P Image Thrombomodulin antibody [C3], C-term detects THBD protein at cytosol and membrane on human gastric cancer by immunohistochemical analysis. Sample: Paraffin-embedded gastric cancer. Thrombomodulin antibody [C3], C-term , dilution: 1:500. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Mouse Rat Un-conjugated CyTOF, FACS, ICC, IHC, WB Detection of Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Mouse Thrombomodulin/BDCA-3 Monoclonal Antibody. Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line. Thrombomodulin/BDCA-3 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Mouse Thrombomodulin/BDCA-3 Monoclonal Antibody  at 10 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsル 557-conjugated Anti-Rat IgG Secondary Antibody (red 100 μg Log in to see 8 to 9 Days
$299.00
Details
Mouse Goat Un-conjugated CyTOF, FACS, ICC, IP, WB Thrombomodulin/BDCA-3 in bEnd.3 Mouse Cell Line. Thrombomodulin/BDCA-3 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-Mouse Thrombomodulin/BDCA-3 Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to cytoplasm. 100 μg Log in to see 8 to 9 Days
$416.30
Details
Human Mouse FITC FACS 1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Mouse Un-conjugated FACS 2 mL Log in to see 6 to 8 Days
$286.00
Details
Human Mouse PE FACS Detection of Thrombomodulin/BDCA-3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human Thrombomodulin/BDCA-3 PE-conjugated Monoclonal Antibody. Quadrant markers were set based on internal control antibody staining. 100 Tests Log in to see 8 to 9 Days
$345.00
Details
Human Mouse Un-conjugated IHC, IHC (p) 250 μL Log in to see 7 to 9 Days
$771.83
Details
Human Mouse Un-conjugated IHC (fro), FACS, IF, IHC (p)   1 mL Log in to see 11 to 13 Days
$751.33
Details

Top referenced anti-Thrombomodulin Antibodies

  1. Human Polyclonal Thrombomodulin Primary Antibody for WB - ABIN2801892 : Suzuki, Kusumoto, Deyashiki, Nishioka, Maruyama, Zushi, Kawahara, Honda, Yamamoto, Horiguchi: Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. in The EMBO journal 1987 (PubMed)
    Show all 5 Pubmed References

  2. Mouse (Murine) Polyclonal Thrombomodulin Primary Antibody for CyTOF, FACS - ABIN4899312 : Schmidt, Yang, Janssen, Gandjeva, Perez, Barthel, Zemans, Bowman, Koyanagi, Yunt, Smith, Cheng, Overdier, Thompson, Geraci, Douglas, Pearse, Tuder: The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. in Nature medicine 2013 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal Thrombomodulin Primary Antibody for FACS, WB - ABIN2192010 : Dömötör, Benzakour, Griffin, Yule, Fukudome, Zlokovic: Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1. in Blood 2003 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal Thrombomodulin Primary Antibody for IHC (fro), FACS - ABIN2478498 : Drake, Loke: Isolation of endothelial cells from human first trimester decidua using immunomagnetic beads. in Human reproduction (Oxford, England) 1992 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal Thrombomodulin Primary Antibody for WB - ABIN2192009 : Tsuneyoshi, Fukudome, Higuchi, Kimoto: Preparation and characterization of monoclonal antibodies to thrombomodulin. in Hybridoma (2005) 2005 (PubMed)
    Show all 2 Pubmed References

  6. Mouse (Murine) Monoclonal Thrombomodulin Primary Antibody for CyTOF, FACS - ABIN4899313 : Belcher, Chen, Nguyen, Milbauer, Abdulla, Alayash, Smith, Nath, Hebbel, Vercellotti: Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. in Blood 2014 (PubMed)

  7. Mouse (Murine) Monoclonal Thrombomodulin Primary Antibody for FACS - ABIN4895906 : Geiger, Pawar, Kerschen, Nattamai, Hernandez, Liang, Fernández, Cancelas, Ryan, Kustikova, Schambach, Fu, Wang, Fink, Petersen, Zhou, Griffin, Baum, Weiler, Hauer-Jensen: Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. in Nature medicine 2012 (PubMed)

  8. Human Monoclonal Thrombomodulin Primary Antibody for FACS - ABIN4896076 : Silk, Silk, Ichiryu, Davies, Nolan, Leishman, Carpenter, Watt, Cerundolo, Fairchild: Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells. in Gene therapy 2012 (PubMed)

  9. Human Monoclonal Thrombomodulin Primary Antibody for FM, IHC (fro) - ABIN2688974 : Teasdale, Bird, Bird: Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain. in Immunology and cell biology 1995 (PubMed)

More Antibodies against Thrombomodulin Interaction Partners

Human Thrombomodulin (THBD) interaction partners

  1. Taken together, our findings suggest that TM-PKCdelta (show PKCd Antibodies) interaction may contribute to cardiovascular disorders by affecting monocye differentiation, which may develop future therapeutic applications.

  2. A heterozygous variant displaying autosomal dominant inheritance (c.1611 C>A) was found in the gene THBD which encodes the glycoprotein thrombomodulin. This sequence change results in a stop codon (p.Cys537Stop) and truncation of the protein

  3. Lys (show LYZ Antibodies) 42, Lys (show LYZ Antibodies) 43, Lys (show LYZ Antibodies) 44 and Arg 12 are critical for the interaction of TAFI (show CPB2 Antibodies) with the thrombin (show F2 Antibodies)-thrombomodulin complex, which modulates its antifibrinolytic potential.

  4. Ligation of anti-HLA class I and II antibodies produces different effects on the endothelial expression of TBM and on serum levels of TBM in transplant recipients.

  5. Fibrinogen gamma acts as thrombomodulin II. (Review)

  6. Thrombomodulin (TM) promotes angiogenesis by enhancing cell adhesion, migration, and FAK (show PTK2 Antibodies) activation through interaction with fibronectin (show FN1 Antibodies).

  7. The elevation of serum thrombomodulin (sTM)level suggests that endothelial damage occurs in Abdominal Aortic Aneurysm pathogenesis.

  8. This population-based cohort study within the ARIC study did not replicate the Hernandez et al. finding that carrying the minor allele of 3 THBD SNPs doubles the risk of venous thromboembolism in African Americans. In fact, the HRs of VTE among carriers of the minor allele were <1. HRs were similar for white subjects. A strand-flip did not explain the discrepancies.

  9. these results suggest a novel function for thrombomodulin as an adhesion molecule in monocytes, where it enhances cell adhesion by binding Ley, leading to beta2 integrin activation via p38 MAPK

  10. TM, especially TME45, maintains vascular integrity, at least in part, via Src (show SRC Antibodies) signaling.

Mouse (Murine) Thrombomodulin (THBD) interaction partners

  1. macrophage infiltration and neointima formation following arterial ligation-induced vascular injury were higher in wild-type than in myeloid-specific thrombomodulin-deficient mice

  2. discovery of a novel physiological function of thrombomodulin-dependent activated protein C (show PROC Antibodies) generation within the CNS

  3. The present study found that the fifth epidermal growth factor (show EGF Antibodies)-like domain of thrombomodulin (TME5) possesses the cytoprotective function in association with an increase in levels of anti-apoptotic myeloid cell leukemia-1 protein in an activated protein C (show PROC Antibodies)-independent

  4. the lectin-like domain of thrombomodulin is critically involved in host defence against E. coli induced acute pyelonephritis

  5. Identified Nur77 (show NR4A1 Antibodies)/Nor1 (show NR4A3 Antibodies) as novel regulators of thrombomodulin expression and function in vascular endothelial cells.

  6. TM expression in corneal epithelium was modulated during the corneal wound healing process, and may be regulated by PDGF (show PDGFA Antibodies)-BB. In addition, rTMD23 has therapeutic potential in corneal injury

  7. Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice

  8. the recombinant epidermal growth factor (show EGF Antibodies)-like domain plus serine/threonine-rich domain of thrombomodulin suppresses the inflammatory response in mice

  9. Thrombomodulin may modulate allergic responses by inhibiting the activation of both eosinophils and mast cells.

  10. Thrombomodulin modulates dendritic cells via both antagonism of high mobility group protein B1 (show HMGB1 Antibodies) and an independent mechanism.

Rabbit Thrombomodulin (THBD) interaction partners

  1. Atorvastin induces THBD expression in the aorta of cholesterol-fed rabbits.

Thrombomodulin (THBD) Antigen Profile

Protein Summary

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

Gene names and symbols associated with anti-Thrombomodulin (THBD) Antibodies

  • thrombomodulin (THBD) antibody
  • thrombomodulin (Thbd) antibody
  • AHUS6 antibody
  • AI385582 antibody
  • BDCA3 antibody
  • CD141 antibody
  • THBD antibody
  • THPH12 antibody
  • THRM antibody
  • TM antibody

Protein level used designations for anti-Thrombomodulin (THBD) Antibodies

thrombomodulin , CD141 antigen , fetomodulin , snoRNA MBII-339 , thrombomdulin , TM

GENE ID SPECIES
469898 Pan troglodytes
702132 Macaca mulatta
100049012 Felis catus
7056 Homo sapiens
474355 Canis lupus familiaris
21824 Mus musculus
83580 Rattus norvegicus
100157642 Sus scrofa
100008887 Oryctolagus cuniculus
100723479 Cavia porcellus
281529 Bos taurus
428546 Gallus gallus
101103256 Ovis aries
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