anti-Thymopoietin (TMPO) Antibodies

The protein encoded by TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. Additionally we are shipping Thymopoietin Kits (15) and Thymopoietin Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TMPO 25359 Q62733
TMPO 7112 P42166 , P42167
TMPO 21917 Q61033 , Q61029
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Top anti-Thymopoietin Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TMPO Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human heart 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TMPO Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  SH-SYSY cell lysate TMPO is strongly supported by BioGPS gene expression data to be expressed in Human SHSY5Y cells WB Suggested Anti-TMPO  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: SH-SYSY cell lysate  TMPO is strongly supported by BioGPS gene expression data to be expressed in Human SHSY5Y cells 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TMPO Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Thymus 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB TMPO Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the TMPO antibody detected the TMPO protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Cow Rabbit Un-conjugated WB Western blot analysis of Thymopoietin expression in HepG2 (A), mouse kidney (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Thymus lysate; Primary Ab: 1µg/ml Rabbit Anti-Human TMPO Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Western Blot; Sample: Human Hela cell lysate; Primary Ab: 1µg/ml Rabbit Anti-Human TMPO Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL 11 to 13 Days
$366.77
Details
Chicken Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using TMPO antibody (ABIN5971365) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat brain using TMPO Antibody (ABIN5971365) at dilution of 1/100 (40x lens). 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB Anti-TMPO / TP / Thymopoietin antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Details

Top referenced anti-Thymopoietin Antibodies

  1. Polyclonal Thymopoietin Primary Antibody for IF, WB - ABIN540646 : Padmakumar, Libotte, Lu, Zaim, Abraham, Noegel, Gotzmann, Foisner, Karakesisoglou: The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope. in Journal of cell science 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal Thymopoietin Primary Antibody for ICC, IF - ABIN4359431 : Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Thymopoietin Interaction Partners

Human Thymopoietin (TMPO) interaction partners

  1. Study found TMPO is significantly upregulated in glioblastoma tissues.TMPO knockdown promoted cell apoptosis by upregulation of the cleavage of caspase-3 and PARP protein levels.

  2. Results suggest that TMPObeta and -gamma isoforms could provide a potential reliable diagnostic marker for breast cancer.

  3. The findings unveil a unique mechanism where the nuclear periphery proteins lamin-A/C, LAP2alpha and BAF1 are assembled into a protein complex during mitosis in order to regulate assembly and positioning of the mitotic spindle.

  4. The authors find that LAP2alpha (lamina-associated polypeptide-alpha) interacts with lamin A, while its interaction with progerin is significantly reduced.

  5. LAP2alpha can regulate extracellular matrix components independently of lamins A/C, which may help explain the proliferation-promoting function of LAP2alpha in cells expressing progerin.

  6. Results highlight the interactions at the nuclear envelope where mutations in the EMD and TMPO gene in combination with mutations in SUN1 have an impact on several components of the network.

  7. Data indicate that cells lacking either high mobility group protein N5 (HMGN5) and lamina-associated polypeptide 2alpha (LAP2alpha) showed that loss of either protein affects the genome-wide distribution of the remaining partner.

  8. this study provides evidence for elevated LAP2alpha expression in cervical cancer and suggests that E2F and p53 activities associate with the positive and negative regulation of LAP2alpha expression, respectively

  9. data suggest that hypophosphorylated Rb is anchored in the nucleus by the interaction of pocket C with LAP2alpha-lamin A/C complexes

  10. Results indicate that in vitro, the interaction between HA95 and LAP2beta is influenced by a PKA-mediated phosphorylation of HA95 rather than by CDK1- or PKC-mediated phosphorylation of LAP2beta

  11. LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly

  12. A predicted Arg690Cys substitution within the LAP2 gene is implicated in the pathogenesis of genetic forms of dilated cardiomyopathy.

  13. The effects of LAP2alpha on cell cycle progression and differentiation may be highly relevant for the cell- and tissue-specific phenotypes observed in laminopathic diseases.

  14. In agreement with its regulation by E2F, LAP2alpha over expression in primary tumors was found to be correlated with tumor proliferation rate

  15. LAP2alpha forms higher order structures containing multiple LAP2alpha molecules in vivo and that complex formation is mediated by the C terminus.

  16. Results suggest that LAP2alpha and lamin A/C are involved in controlling retinoblastoma protein localization and phosphorylation, and a lack or mislocalization of either protein leads to cell cycle arrest in fibroblasts.

  17. Lamina associated protein 2Beta (LAP2beta) is expressed in acute hematopoietic malignant cells, but not in chronic hematopoietic malignant cells.

  18. Co-expression of LAP2beta and LAP2zeta results in inhibition of LAP2beta-induced gene silencing while overexpression of LAP2zeta alone leads to a small increase in transcriptional activity of various transcription factors.

Cow (Bovine) Thymopoietin (TMPO) interaction partners

  1. Lamin-associated polypeptide (LAP)2 beta assembles around only alternative oocyte chromatin after complete dephosphorylation of histone H3 following fertilization and activation. (lamina-associated polypeptide 2; LAP2beta)

Mouse (Murine) Thymopoietin (TMPO) interaction partners

  1. Lifespan and body mass were increased in Lmna(-/-)Lap2alpha(-/-) mice compared with Lmna deficient mice.

  2. Data indicate that a LAP2alpha-independent assembly defect of DeltaK32 lamin A/C is the cause of the pathology, whereas the LAP2alpha-linked functions of nucleoplasmic lamin A/C in the regulation of tissue progenitor cells are not affected in Lmna(DeltaK32/DeltaK32) mice.

  3. LAP2alpha serves as a transcriptional co-regulator, which controls muscle specific gene expression during muscle regeneration, muscle remodeling and stress response.

  4. TSLP diverts airway tolerance against ovalbumin (OVA) to T helper cell type (Th)2 sensitization and inhibits the generation of OVA-specific inducible regulatory T cells.

  5. The age-related down-regulation of Wnt4 (and subsequently FoxN1), and the prominent increase in LAP2alpha expression, was investigated in thymic epithelial cells.

  6. Our data demonstrate multiple and distinct functions of LAP2 alpha in muscle stem cell maintenance, early phases of myogenic differentiation, and muscle remodeling.

  7. Data show that LAP2alpha knockout caused systolic dysfunction in young mice, sporadic fibrosis in old animals, and disregulation of cardiac GATA4 and MEF2c, while dstrophin deficiency in Mdx mice resulted in a transient rescue of Lap2alpha(-/-) phenotype.

  8. In agreement with its regulation by E2F, LAP2alpha over expression in primary tumors was found to be correlated with tumor proliferation rate

  9. LAP2alpha is dispensable for murine leukemia infections.

  10. Loss of LAP2-Lmna complexes causes erythroid and epidermal progenitor hyperproliferation.

Thymopoietin (TMPO) Antigen Profile

Protein Summary

The protein encoded by this gene resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with anti-Thymopoietin (TMPO) Antibodies

  • thymopoietin (TMPO) antibody
  • thymopoietin (Tmpo) antibody
  • thymopoietin S homeolog (tmpo.S) antibody
  • thymopoietin a (tmpoa) antibody
  • 5630400D24Rik antibody
  • AI195756 antibody
  • AI606875 antibody
  • AW214352 antibody
  • AW547477 antibody
  • CMD1T antibody
  • lap2 antibody
  • LAP2beta antibody
  • LEMD4 antibody
  • PRO0868 antibody
  • tmpo antibody
  • TP antibody
  • wu:fc26f12 antibody
  • wu:fd21f02 antibody
  • wu:fi29h05 antibody

Protein level used designations for anti-Thymopoietin (TMPO) Antibodies

thymopoietin , lamina-associated polypeptide 2, isoform alpha-like , TP beta , Thymopoietin (lamina associated polypeptide 2) , lamina-associated polypeptide 2 , thymopoietin isoform beta , LEM domain containing 4 , TP alpha , TP beta/gamma , thymopoietin-related peptide isoform alpha , thymopoietin-related peptide isoforms beta/gamma , lamina associated polypeptide 2 , lamin-associated polypeptide 2beta , thymopoietin II , thymopoietin-2 , etID53005.4 , lamina-associated protein 2

GENE ID SPECIES
452151 Pan troglodytes
693387 Macaca mulatta
100387152 Callithrix jacchus
100457982 Pongo abelii
100588465 Nomascus leucogenys
25359 Rattus norvegicus
7112 Homo sapiens
397975 Xenopus laevis
417923 Gallus gallus
482618 Canis lupus familiaris
510267 Bos taurus
21917 Mus musculus
352907 Danio rerio
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