anti-Topoisomerase (DNA) II beta 180kDa Antibodies

TOP2B encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription.

Data Quality
  • 23
Type
  • 78
    Primary antibodies
Antigen
  • 78
Reactivity
  • 76
  • 37
  • 8
  • 7
  • 5
Application
  • 49
  • 36
  • 33
  • 13
  • 11
Host
  • 76
  • 2
Clonality
  • 76
  • 1
Binding Specificity
  • 8
  • 5
  • 4
  • 4
  • 2
Conjugate
  • 54
  • 4
  • 3
  • 3
  • 3
Isotype
  • 30
Format
  • 44
  • 6
Suggested next Filters
78 Products
ReactivityHuman
Application IP, IHC (p), WB
Order details Cat. No. ABIN2855447
$509.08
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman, Mouse (Murine)
Application ELISA, ICC, IF, IHC, WB
Order details Cat. No. ABIN6265674
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityDog (Canine), Human, Monkey, Pig (Porcine)
Application IC, IF, IHC, WB
Order details Cat. No. ABIN2707765
$487.50
200 μL
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN927425
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN927692
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityCow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
Application WB
Order details Cat. No. ABIN2780351
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse (Murine)
Application IHC, ELISA, WB
Order details Cat. No. ABIN1848858
$323.60
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman, Mouse (Murine)
Application IHC, ELISA, WB
Order details Cat. No. ABIN1533446
$324.50
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse (Murine)
Application IHC (p), WB
Order details Cat. No. ABIN271965
$434.50
0.1 mg
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application IHC (p), WB
Order details Cat. No. ABIN5589943
$460.00
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, WB
Order details Cat. No. ABIN2434033
$493.90
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
ReactivityHuman
Application ICC, IF, IHC, WB
Order details Cat. No. ABIN5620998
$295.43
100 μL
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine)
Application ELISA, IHC (p), WB
Order details Cat. No. ABIN6280524
$309.14
50 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application IHC, ELISA, WB
Order details Cat. No. ABIN2153594
$369.29
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine)
Application ELISA, IHC, WB
Order details Cat. No. ABIN3187306
$369.83
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
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Topoisomerase (DNA) II beta 180kDa (TOP2B) Antigen Profile

Protein Summary

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants\; however, the second variant has not yet been fully described.

Gene names and symbols associated with TOP2B

  • DNA topoisomerase II beta (TOP2B) antibody
  • topoisomerase (DNA) II beta (Top2b) antibody
  • DNA topoisomerase II beta (Top2b) antibody
  • microRNA 4442 (MIR4442) antibody
  • D230016L12Rik antibody
  • Top-2 antibody
  • TOP2B antibody
  • top2beta antibody
  • TOPIIB antibody

Protein level used designations for TOP2B

topoisomerase (DNA) II beta 180kDa , DNA topoisomerase II, beta isozyme , DNA topoisomerase 2-beta , topoisomerase II beta , DNA topoisomerase II beta , DNA topoisomerase II, 180 kD , U937 associated antigen , antigen MLAA-44 , topo II beta , topoisomerase IIb , DNA topoisomeraseII_beta , topoisomerase II beta-2

GENE ID SPECIES
460232 Pan troglodytes
21974 Mus musculus
361100 Rattus norvegicus
7155 Homo sapiens
395966 Gallus gallus