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SUPT5H Proteins

(Transcription Elongation Factor SPT5 (SUPT5H))

Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV- 1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.

recommended

SUPT5H Protein (AA 981-1087) (GST tag) (ABIN1321917)

SUPT5H Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

SUPT5H Protein (AA 1-1087) (Strep Tag) (ABIN3095662)

Crystallography grade SUPT5H Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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recommended

SUPT5H Protein (AA 1-1082) (Strep Tag) (ABIN3131899)

Crystallography grade SUPT5H Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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SUPT5H Proteins by Grade

Find SUPT5H Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SUPT5H Proteins by Origin

Find SUPT5H Proteins for a variety of species such as anti-Human SUPT5H, anti-Mouse SUPT5H. The species listed below are among those available. Click on a link to go to the corresponding products.

SUPT5H Proteins by Source

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SUPT5H Proteins by Protein Type

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SUPT5H Proteins by Application

Find SUPT5H Proteins validated for a specific application such as AbP, STD, ELISA, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SUPT5H Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

SUPT5H Protein (AA 981-1087) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1321917

Quantity 10 μg

Datasheet Datasheet

SUPT5H Protein (AA 1-1087) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3095662

Quantity 1 mg

Datasheet Datasheet

SUPT5H Protein (AA 1-1082) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3131899

Quantity 1 mg

Datasheet Datasheet

SUPT5H Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2733007

Quantity 20 μg

Datasheet Datasheet

SUPT5H Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2733008

Quantity 20 μg

Datasheet Datasheet

SUPT5H Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2733009

Quantity 20 μg

Datasheet Datasheet

SUPT5H Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2733010

Quantity 20 μg

Datasheet Datasheet

Aliases for SUPT5H Proteins

SPT5 homolog, DSIF elongation factor subunit (SUPT5H) Proteins
transcription elongation factor SPT5 (LOC413814) Proteins
Transcription elongation factor Spt5 (AT2G34210) Proteins
transcription elongation factor Spt5 (spt5) Proteins
transcription elongation factor spt5 (MGYG_08422) Proteins
transcription elongation factor spt5 (TERG_05483) Proteins
hypothetical protein (PGTG_18458) Proteins
SPT5 homolog, DSIF elongation factor subunit (supt5h) Proteins
SPT5 homolog, DSIF elongation factor subunit (Supt5h) Proteins
SPT5 homolog, DSIF elongation factor subunit S homeolog (supt5h.S) Proteins
CG7626 gene product from transcript CG7626-RA (Spt5) Proteins
Transcription elongation factor SPT5 (spt-5) Proteins
transcription elongation factor (SPT5) Proteins
CaO19.1453 Proteins
CG7626 Proteins
dDSIF Proteins
Dmel\\CG7626 Proteins
DSIF Proteins
Dspt5 Proteins
dSpt5 Proteins
etID10129.15 Proteins
etID37101.15 Proteins
F13P17.5 Proteins
F13P17_5 Proteins
fb37g01 Proteins
fb95e05 Proteins
fog Proteins
foggy Proteins
SPT5 Proteins
Spt5 Proteins
spt5 Proteins
SPT5H Proteins
spt5h Proteins
Tat-CT1 Proteins
tat-ct1 Proteins
wu:fb37g01 Proteins
wu:fb95e05 Proteins
wu:fc10f02 Proteins

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SUPT5H Proteins by Grade

SUPT5H Proteins by Origin

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SUPT5H Proteins by Application

Popular SUPT5H Proteins

Aliases for SUPT5H Proteins

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