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Transcription Elongation Factor SPT5 Proteins

Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II.

7 results:

Transcription Elongation Factor SPT5 (SUPT5H) (AA 1-1087) protein (His tag) Protein

SUPT5H Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3095662
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days
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Transcription Elongation Factor SPT5 (SUPT5H) (AA 1-1082) protein (His tag) Protein

SUPT5H Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3131899
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days
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Transcription Elongation Factor SPT5 (SUPT5H) (AA 981-1087) protein (GST tag) Protein

SUPT5H Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1321917
$414.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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Transcription Elongation Factor SPT5 (SUPT5H) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein

SUPT5H Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2733010
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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Transcription Elongation Factor SPT5 (SUPT5H) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag) Protein

SUPT5H Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2733008
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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Transcription Elongation Factor SPT5 (SUPT5H) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein

SUPT5H Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2733009
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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Transcription Elongation Factor SPT5 (SUPT5H) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

SUPT5H Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2733007
$932.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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  • Type Protein
    • Protein
  • Target Transcription Elongation Factor SPT5 (SUPT5H)
    • Transcription Elongation Factor SPT5 (SUPT5H)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Interleukin 15 (IL15)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • Reactivity
    • Human
    • Mouse
  • Images available
  • Host
    • HEK-293 Cells
    • Insect Cells
    • Wheat germ
  • Binding Specificity
    • AA 1-1082
    • AA 1-1087
    • AA 981-1087
    • Transcript Variant 1
    • Transcript Variant 2
    • Transcript Variant 3
    • Transcript Variant 4
  • Conjugate
    • Un-conjugated
    • Myc-DYKDDDDK Tag
    • His tag
    • GST tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid

Transcription Elongation Factor SPT5 (SUPT5H) Protein Profile

Protein Summary

Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV- 1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.

Gene names and symbols associated with SUPT5H

  • SPT5 homolog, DSIF elongation factor subunit (SUPT5H) antibody
  • transcription elongation factor SPT5 (LOC413814) antibody
  • Transcription elongation factor Spt5 (AT2G34210) antibody
  • transcription elongation factor Spt5 (spt5) antibody
  • transcription elongation factor spt5 (MGYG_08422) antibody
  • transcription elongation factor spt5 (TERG_05483) antibody
  • hypothetical protein (PGTG_18458) antibody
  • SPT5 homolog, DSIF elongation factor subunit (supt5h) antibody
  • SPT5 homolog, DSIF elongation factor subunit (Supt5h) antibody
  • SPT5 homolog, DSIF elongation factor subunit S homeolog (supt5h.S) antibody
  • CG7626 gene product from transcript CG7626-RA (Spt5) antibody
  • Transcription elongation factor SPT5 (spt-5) antibody
  • transcription elongation factor (SPT5) antibody
  • CaO19.1453 antibody
  • CG7626 antibody
  • dDSIF antibody
  • Dmel\\CG7626 antibody
  • DSIF antibody
  • dSpt5 antibody
  • etID10129.15 antibody
  • etID37101.15 antibody
  • F13P17.5 antibody
  • F13P17_5 antibody
  • fb37g01 antibody
  • fb95e05 antibody
  • fog antibody
  • foggy antibody
  • spt5 antibody
  • spt5h antibody
  • tat-ct1 antibody
  • wu:fb37g01 antibody
  • wu:fb95e05 antibody
  • wu:fc10f02 antibody

Protein level used designations for SUPT5H

DRB sensitivity-inducing factor 160 kDa subunit , DRB sensitivity-inducing factor large subunit , DSIF large subunit , DSIF p160 , Tat-cotransactivator 1 protein , hSPT5 , transcription elongation factor SPT5 , transcription elongation factor Spt5 , transcription elongation factor spt5 , protein foggy , transcription elongation regulator foggy , CG7626-PA , Spt5-PA , Chromatin elongation factor SPT5

GENE ID SPECIES
6829 Homo sapiens
413814 Apis mellifera
817982 Arabidopsis thaliana
2541916 Schizosaccharomyces pombe 972h-
10024747 Arthroderma gypseum CBS 118893
10372474 Trichophyton rubrum CBS 118892
10537737 Puccinia graminis f. sp. tritici CRL 75-36-700-3
64275 Danio rerio
308472 Rattus norvegicus
426493 Gallus gallus
476462 Canis lupus familiaris
733281 Xenopus laevis
519808 Bos taurus
53442 Drosophila melanogaster
178143 Caenorhabditis elegans
100713914 Cavia porcellus
3635847 Candida albicans SC5314

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