Transcription Factor 20 Proteins (TCF20)

The protein encoded by TCF20 binds a platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 (stromelysin 1) promoter. Additionally we are shipping TCF20 Antibodies (27) and TCF20 Kits (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TCF20 21411  
Rat TCF20 TCF20 366964  
Human TCF20 TCF20 6942 Q9UGU0
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Top TCF20 Proteins at

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Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Mouse His tag   100 μg 15 to 18 Days

TCF20 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

More Proteins for Transcription Factor 20 (TCF20) Interaction Partners

Human Transcription Factor 20 (TCF20) interaction partners

  1. TCF20 pathogenic variants are associated with a novel syndrome manifesting clinical characteristics similar to those observed in Smith-Magenis syndrome.

  2. Nonsense and one frameshift variant of TCF20 were identified the patients with intellectual disability and postnatal overgrowth. Such de novo variants of TCF20 may represent a novel differential diagnosis in the overgrowth syndrome spectrum.

  3. mutations in TCF20 are associated with Autism spectrum disorders

  4. SPBP is a transcriptional coactivator of NRF2 regulating expression of the autophagy receptor p62.

  5. evolutionary conservation of chromatin binding of SPBP and RAI1

  6. Study has identified SPBP as a transcriptional coactivator of AR. We also show that Pax6 inhibits SPBP-mediated enhancement of AR activity on the AR target gene probasin promoter, a repression that was partly reversed by increased expression of SPBP.

  7. SPBP behaves as a repressor of activated ERalpha

  8. Interaction between SPBP and TopBP1 was found to be mediated by the ePHD domain of SPBP and the BRCT6 domain of TopBP1.

TCF20 Protein Profile

Protein Summary

The protein encoded by this gene binds a platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 (stromelysin 1) promoter. The protein localizes to the nucleus and displays DNA-binding and transactivation activities. It is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with TCF20

  • transcription factor 20 (Tcf20)
  • transcription factor 20 (TCF20)
  • 2810438H08Rik protein
  • AR1 protein
  • mKIAA0292 protein
  • SPBP protein
  • TCF-20 protein

Protein level used designations for TCF20

SPRE-binding protein , TCF-20 , nuclear factor SPBP , stromelysin 1 PDGF responsive element binding protein , stromelysin 1 PDGF-responsive element-binding protein , stromelysin PDGF responsive element binding protein transcription factor , stromelysin-1 PDGF-responsive element-binding protein , stromelysin-1 platelet-derived growth factor-responsive element binding protein , transcription factor 20

21411 Mus musculus
366964 Rattus norvegicus
6942 Homo sapiens
100348277 Oryctolagus cuniculus
100719788 Cavia porcellus
481224 Canis lupus familiaris
100511754 Sus scrofa
523151 Bos taurus
417980 Gallus gallus
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