anti-Transcription Factor B1, Mitochondrial (TFB1M) Antibodies

The protein encoded by TFB1M is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. Additionally we are shipping TFB1M Proteins (12) and TFB1M Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TFB1M 51106 Q8WVM0
TFB1M 224481 Q8JZM0
TFB1M 308140 Q811P6
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Top anti-TFB1M Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-TFB1M Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Liver WB Suggested Anti-TFB1M antibody Titration: 1 ug/mL Sample Type: Human liver 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TFB1M Antibody Titration:  2.5ug/ml  ELISA Titer:  1:312500  Positive Control:  721_B cell lysate TFB1M is supported by BioGPS gene expression data to be expressed in 721_B WB Suggested Anti-TFB1M  Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate  TFB1M is supported by BioGPS gene expression data to be expressed in 721_B 100 μL 2 to 3 Days
$249.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$507.83
Details
Human Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$610.50
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Mouse Un-conjugated WB   100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of TFB1M expression in transfected 293T cell line by TFB1M MaxPab polyclonal antibody.Lane 1: TFB1M transfected lysate(38.17 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Goat Un-conjugated ELISA, WB TFB1M polyclonal antibody  (0.3 ug/mL) staining of A-431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 11 to 12 Days
$374.67
Details

Top referenced anti-TFB1M Antibodies

  1. Human Polyclonal TFB1M Primary Antibody for ELISA, WB - ABIN4358618 : Sánchez-Ferrero, Coto, Blázquez, Ribacoba, Guisasola, Salvador, Alvarez: Mutational screening of the mitochondrial transcription factors B1 and B2 (TFB1M and TFB2M) in Parkinson's disease. in Parkinsonism & related disorders 2009 (PubMed)

More Antibodies against TFB1M Interaction Partners

Human Transcription Factor B1, Mitochondrial (TFB1M) interaction partners

  1. Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.

  2. Deficiency in TFB1M and impaired mitochondrial function contribute to the pathogenesis of type 2 diabetes.

  3. The mRNA levels of TFB1M and TFB2M are influenced by endurance training

  4. This transcription factor activates transcription of human mitochondrial DNA.

  5. Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop

  6. TFB1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity

  7. TFB1M is a nuclear-encoded modifier gene for phenotypic expression of the deafness-associated homoplasmic A1555G mutation in the mitochondrial 12S rRNA gene.

  8. Distinct, but possibly coordinated functions of mtTFB1 and mtTFB2 in mitochondrial gene expression and biogenesis.

  9. This study suggested that DNA variants in TFB1M did not contribute to the risk for parkinson disease.

  10. determined the variation in the TFAM, TFB1M, and TFB2M genes in cardiac hypertrophy

  11. rRNA methyltransferase activity is necessary for induction of mitochondrial biogenesis by TFB1M, but not TFB2M.

Mouse (Murine) Transcription Factor B1, Mitochondrial (TFB1M) interaction partners

  1. Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.

  2. Metazoans have two TFBM genes, suggesting that a duplication of the gene has permitted a more flexible regulation of mtDNA.

Cow (Bovine) Transcription Factor B1, Mitochondrial (TFB1M) interaction partners

  1. Lethal haplotype 5 (HH5) is caused by a deletion of 138kbp, spanning position 93,233kb to 93,371kb on chromosome 9 (BTA9), harboring only dimethyl-adenosine transferase 1 (TFB1M).

TFB1M Antigen Profile

Protein Summary

The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).

Gene names and symbols associated with TFB1M

  • transcription factor B1, mitochondrial (TFB1M) antibody
  • transcription factor B1, mitochondrial L homeolog (tfb1m.L) antibody
  • transcription factor B1, mitochondrial (tfb1m) antibody
  • transcription factor B1, mitochondrial (Tfb1m) antibody
  • Mitochondrial Transcription Factor B1 (mtTFB1) antibody
  • AI429207 antibody
  • CG7319 antibody
  • CG42631 antibody
  • CGI-75 antibody
  • cgi75 antibody
  • d-mtTFB1 antibody
  • d-TFB1M antibody
  • Dmel\\CG42631 antibody
  • Dmel_CG7319 antibody
  • im:7151479 antibody
  • mttfb antibody
  • mttfb1 antibody
  • TFB1 antibody
  • zgc:153625 antibody

Protein level used designations for TFB1M

S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1 , dimethyladenosine transferase 1, mitochondrial , h-mtTFB1 , hTFB1M , homolog of yeast mitochondrial transcription factor B , mitochondrial 12S rRNA dimethylase 1 , mitochondrial dimethyladenosine transferase 1 , mitochondrial transcription factor B1 , mtTFB1 , transcription factor B1, mitochondrial , Mitochondrial dimethyladenosine transferase 1, mitochondrial , dimethyladenosine transferase 1, mitochondrial-like , CG42631-PA , mitochondrial translation factor B1 , mtTFB1-PA

GENE ID SPECIES
51106 Homo sapiens
379540 Xenopus laevis
428608 Gallus gallus
476253 Canis lupus familiaris
549248 Xenopus (Silurana) tropicalis
701830 Macaca mulatta
737921 Pan troglodytes
100147809 Sus scrofa
100173901 Pongo abelii
100391680 Callithrix jacchus
224481 Mus musculus
308140 Rattus norvegicus
533438 Bos taurus
767802 Danio rerio
8674019 Drosophila melanogaster
100715032 Cavia porcellus
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