TFB1M antibody (N-Term)

Catalog No. ABIN2775859

This Rabbit Polyclonal antibody specifically detects TFB1M in WB and IHC. It exhibits reactivity toward Human, Rat, Cow, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio) and Rabbit.

Quick Overview for TFB1M antibody (N-Term) (ABIN2775859)

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Reactivity: Human, Rat, Cow, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFB1M antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TFB1M Antibody

Binding Specificity: N-Term

Purpose: TFB1M Antibody - N-terminal region

Sequence: NFLLDLRLTD KIVRKAGNLT NAYVYEVGPG PGGITRSILN ADVAELLVVE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against TFB1M. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFB1M

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34543-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFB1M

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Alternative Name: TFB1M

Background:

Background Information: The transcription of genes from mitochondrial DNA requires a mitochondrial RNA polymerase and a DNA-binding transcription factor. Transcription factor B1 (TFB1M) is a part of this transcription complex. The transcription of genes from mitochondrial DNA requires a mitochondrial RNA polymerase (see POLRMT, MIM 601778) and a DNA-binding transcription factor (see TFAM, MIM 600438). Transcription factor B1 (TFB1M) is a part of this transcription complex.[supplied by OMIM].

Gene Name: Transcription factor B1, mitochondrial

Alternative Symbols: CGI75, mtTFB, CGI-75, mtTFB1

Protein Name: Dimethyladenosine transferase 1, mitochondrial

Molecular Weight: 39kDa

Gene ID: 51106

NCBI Accession: NP_057104

UniProt: Q8WVM0