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The protein encoded by TBL1Y has sequence similarity with members of the WD40 repeat-containing protein family. Additionally we are shipping TBL1Y Antibodies (59) and TBL1Y Kits (12) and many more products for this protein.
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reducing TBL1Y cellular level using siRNA approach influenced cardiac differentiation by reducing its efficacy as well as increasing the probability of impaired contractions; proposed reclassification of TBL1Y as "found missing protein"
TBL1 is required to protect GPS2 from degradation, with methylation of GPS2 by arginine methyltransferase PRMT6 regulating the interaction with TBL1 and inhibiting proteasome-dependent degradation.
Our findings suggest that TBL1Y is involved in the genesis of non-syndromic coarctation of the aorta.
Taken together,these findings suggest that TBL1 controls NF-kB activation by recruiting NF-kB to its target gene promoter.
investigated 12 single-nucleotide polymorphisms in Y-linked neuroligin 4, transducin b-like 1, and eukaryotic translation initiation factor 1a genes, results suggest a Y chromosome effect in autism
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein.
F-box-like/WD repeat-containing protein TBL1Y
, transducin beta-like 1
, transducin beta-like protein 1Y
, transducin-beta-like protein 1, Y-linked