Transglutaminase 5 Proteins (TGM5)

TGM5 encodes a member of the transglutaminase family. Additionally we are shipping Transglutaminase 5 Antibodies (64) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TGM5 9333 O43548
TGM5 74176 Q9D7I9
Rat TGM5 TGM5 691929  
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Top Transglutaminase 5 Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days

TGM5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Transglutaminase 5 (TGM5) Interaction Partners

Human Transglutaminase 5 (TGM5) interaction partners

  1. Acral PSS (APSS) (OMIM 609796), typically non-inflammatory, is confined to distal extremities with localized exfoliation of the epidermis. It is caused by mutations in the TGM5 gene, encoding transglutaminase 5[3] or in the CTSA gene, encoding cystatin A and it is inherited in autosomal recessive pattern

  2. We report both European and non-European families with acral peeling skin syndrome carrying mutations in the TGM5 gene. In 5 patients, we found 3 novel mutations: c.1001+2_1001+3del, c.1171G>A and c.1498C>T.

  3. Data trebles the number of TMG5 mutations and provides further evidence that pCly113Cys is a founder mutation in the European population.

  4. study concludes polymorphisms of TGM5, PPAP2B and PSMA4 are not major contributors tonon-small cell lung cancer susceptibility in never-smoking hinese population, this primarily can be attributed to the significantly distinct genetic background of Asian populations from western populations

  5. Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.

  6. TGM5 mutations impact epidermal differentiation in acral peeling skin syndrome.

  7. analysis of a recurrent mutation in the TGM5 gene in European patients with acral peeling skin syndrome

  8. Acral peeling skin syndrome with TGM5 gene mutations may resemble epidermolysis bullosa simplex in young individuals.

  9. transglutaminase 5 contributes, as a secondary effect, to the hyperkeratotic phenotype in ichthyosis (both vulgaris and lamellar) and in psoriasis.

  10. Results demonstrate that transglutaminase 5 is able to induce cell death when intracellularly overexpressed.

  11. Data show that transglutaminase (TGase) 5 is acetylated at the N-terminal end, is active upon treatment with phorbol acetate, and co-localises with vimentin intermediate filaments.

  12. Transglutaminase 5 is expressed during hair follicle homeostasis.

  13. A homozygous missense mutation in TGM5 abolishes epidermal TGM5 activity and causes acral peeling skin syndrome.

  14. TG5 full-length enzyme has very low enzymatic activity, while the 53-kDa proteolytically processed form is highly active.

  15. A missense mutation in TGM5 causes acral peeling skin syndrome in a Tunisian family.

Transglutaminase 5 (TGM5) Protein Profile

Protein Summary

This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.

Gene names and symbols associated with Transglutaminase 5 Proteins (TGM5)

  • transglutaminase 5 (TGM5)
  • transglutaminase 5 (tgm5)
  • transglutaminase 5 (Tgm5)
  • 2310007C07Rik protein
  • TGASE5 protein
  • TGASEX protein
  • TGM5 protein
  • TGMX protein
  • TGx protein

Protein level used designations for Transglutaminase 5 Proteins (TGM5)

transglutaminase 5 , protein-glutamine gamma-glutamyltransferase 5-like , TG(X) , TGase X , TGase-5 , protein-glutamine gamma-glutamyltransferase 5 , transglutaminase V , transglutaminase X , transglutaminase-5 , TGase 5

453375 Pan troglodytes
712605 Macaca mulatta
100359233 Oryctolagus cuniculus
100459707 Pongo abelii
100486682 Xenopus (Silurana) tropicalis
100604663 Nomascus leucogenys
100623920 Sus scrofa
9333 Homo sapiens
487522 Canis lupus familiaris
514767 Bos taurus
74176 Mus musculus
691929 Rattus norvegicus
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