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Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Additionally we are shipping Translocase of Inner Mitochondrial Membrane 22 Homolog (Yeast) Antibodies (6) and Translocase of Inner Mitochondrial Membrane 22 Homolog (Yeast) Proteins (3) and many more products for this protein.
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The dual function of AGK as lipid kinase and constituent of the TIM22 complex reveals that disturbances in both phospholipid metabolism and mitochondrial protein biogenesis contribute to the pathogenesis of Sengers syndrome.
Identify AGK as a bona fide subunit of TIM22 providing an exciting and unexpected link between mitochondrial protein import and Sengers syndrome.
in contrast to yeast, only a small fraction of Tim9 (show TIMM9 ELISA Kits)-Tim10a (show TIMM10 ELISA Kits)-Tim10b complex is in a stable association with Tim22.
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
mitochondrial import inner membrane translocase subunit Tim22
, preprotein translocase
, translocase of inner mitochondrial membrane 22 homolog
, putative membrane protein
, testis-expressed sequence 4