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Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Additionally we are shipping TFF3 Antibodies (147) and TFF3 Proteins (42) and many more products for this protein.
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Human TFF3 ELISA Kit for Sandwich ELISA - ABIN414858
Huang, Zhang, Lu, Wu, Wang, Zhang, Ding: Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: a monocentric cohort study in China. in BMC gastroenterology 2014
Show all 4 Pubmed References
trefoil factors family 3 may have a role in colorectal cancer
This study provides the first evidence that TFF3 is locally elevated in the peritoneal cavity in endometriosis and might play a role in disease pathogenesis and its associated inflammatory processes. Furthermore, the results show that TFF3 is regulated through the menstrual cycle.
involvement of TFF3 in the pathogenesis of rhonchopathy and OSA
Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 (show DEFB4 ELISA Kits) and trefoil factor 3 and attenuates attaching and effacing bacteria-induced intestinal disease.(
The expression of TFF3 and TWIST1 (show TWIST1 ELISA Kits) might be associated with the survival of patients with colorectal cancer (CRC (show CALR ELISA Kits)) after curative resection and might be pivotal predictors of disease progression. TFF3 may be correlated to the invasiveness of CRC (show CALR ELISA Kits).
Serum TFF-3 is not a convenient and reliable surrogate marker of mucosal healing during therapy with TNF-alpha antagonists in Crohn's disease.
TFF3 levels differed among idiopathic pulmonary fibrosis, pulmonary sarcoidosis and chronic pulmonary obstructive disease.
TFF3 protein knockout can facilitate apoptosis of human pituitary adenoma HP75 cells via mitochondrial pathway
Data show that trefoil factor-3 (TFF3) secreted from mammary carcinoma cells promotes de novo angiogenesis via interleukin-8 (IL-8 (show IL8 ELISA Kits))/IL-8 (show IL8 ELISA Kits) receptor (show CXCR1 ELISA Kits) CXCR2 (show CXCR2 ELISA Kits).
Dimers CXCR4 (show CXCR4 ELISA Kits) and CXCR7 (show CXCR7 ELISA Kits) are involved in TFF3-dependent activation of cell migration, but not cell proliferation. The ERK1/2 (show MAPK1/3 ELISA Kits) pathway is activated in the process, but not influenced by CXCR4 (show CXCR4 ELISA Kits) or CXCR7 (show CXCR7 ELISA Kits).
These studies reveal a new link between hepatic GALE (show GALE ELISA Kits) activity and whole-body glucose homeostasis via regulation of hepatic Tff3 expression.
the Tg(Tff1 (show TFF1 ELISA Kits)-CreERT2;Tff2 (show TFF2 ELISA Kits)-rtTA;Tff3-Luc) strain can confer intermittent transgene expression to gastric epithelial cells that have undergone previous gene modification, and may be suitable to genetically model therapeutic intervention during development, tumorigenesis, and other genetically tractable diseases
TFF3 is regulated by food intake, improves glucose tolerance and induces mucinous metaplasia.
TFF1 (show TFF1 ELISA Kits) and TFF3 peptides might be involved in the complex processes of nervous system development and differentiation and brain plasticity.
The TFF3 was present in cartilage chondrocytes undergoing endochondral ossification, particularly in zone of proliferation, hypertrophy and calcification as well as in zone of cartilage degeneration during the monitored fetal period.
Intravenous administration of recombinant TFF3 reversed changes in cerebral injury.
Tff3 peptides are involved in glucose homeostasis and insulin (show INS ELISA Kits) sensitivity, providing a promising peptide on new therapies against the metabolic disorders associated with type 2 diabetes mellitus.
The genetically deleting Tff3 in mice altered down-regulated Pttg1 (show PTTG1 ELISA Kits) and up-regulated serpina3n (show SERPINA3N ELISA Kits) expression, indicating a potential role of these factors during the development of presbyacusis.
Tff3 knock out mice have lower body weight than wild-type mice.
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
trefoil factor 3 (intestinal)
, intestinal trefoil factor
, trefoil factor 3
, Intestinal trefoil factor
, trefoil factor family peptide 3
, polypeptide P1.B