Tripartite Motif Containing 56 Proteins (TRIM56)

E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. Additionally we are shipping TRIM56 Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRIM56 81844 Q9BRZ2
TRIM56 384309 Q80VI1
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Top TRIM56 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

TRIM56 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Tripartite Motif Containing 56 (TRIM56) Interaction Partners

Human Tripartite Motif Containing 56 (TRIM56) interaction partners

  1. SopA inhibits TRIM56 E3 ligase activity by occluding the E2-interacting surface of TRIM56.

  2. TRIM56 E3 ligase-induced monoubiquitination of cGAS is important for cytosolic DNA sensing and IFNalphabeta production to induce anti-DNA viral immunity.

  3. TRIM56 may act as a tumor suppressor in multiple myeloma through activation of TLR3 (show TLR3 Proteins)/TRIF (show TRIM69 Proteins) signaling pathway.

  4. TRIM56 is the ubiquitin ligase that is degrading vimentin (show VIM Proteins) in ovarian cancer cells, regulation cell migration and neoplasm invasiveness.

  5. The C-Terminal Tail of TRIM56 Dictates Antiviral Restriction of Influenza A and B Viruses by Impeding Viral RNA Synthesis

  6. Altogether, TRIM56 is a versatile antiviral host factor that confers resistance to yellow fever virus, dengue virus serotype 2, and human coronavirus OC43 through overlapping and distinct molecular determinants

  7. TRIM56 is an essential component of the TLR3 (show TLR3 Proteins) antiviral signaling pathway and reveal a novel role for TRIM56 in innate antiviral immunity.

  8. TRIM56 is a target gene of the BACH1 (show BACH1 Proteins) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 Proteins) 293 cells.

  9. These data demonstrate that TRIM56 is a novel antiviral host factor that restricts pestivirus infection.

  10. TRIM56 is an interferon (show IFNA Proteins)-inducible E3 ubiquitin ligase (show MUL1 Proteins) that modulates STING to confer double-stranded DNA-mediated innate immune responses.

TRIM56 Protein Profile

Protein Summary

E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA.

Gene names and symbols associated with TRIM56

  • tripartite motif containing 56 (TRIM56)
  • tripartite motif-containing 56 (Trim56)
  • A130009K11Rik protein
  • Gm452 protein
  • RNF109 protein
  • TRIM56 protein

Protein level used designations for TRIM56

tripartite motif-containing 56 , tripartite motif-containing protein 56-like , tripartite motif containing 56 , E3 ubiquitin-protein ligase TRIM56 , RING finger protein 109 , tripartite motif-containing protein 56

GENE ID SPECIES
472466 Pan troglodytes
100060136 Equus caballus
100356761 Oryctolagus cuniculus
100435513 Pongo abelii
100484728 Ailuropoda melanoleuca
100585676 Nomascus leucogenys
81844 Homo sapiens
608281 Canis lupus familiaris
514896 Bos taurus
384309 Mus musculus
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