Tripartite Motif Containing 6 Proteins (TRIM6)

The protein encoded by TRIM6 is a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM6 Antibodies (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRIM6 117854 Q9C030
Rat TRIM6 TRIM6 293294  
TRIM6 94088 Q8BGE7
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Top TRIM6 Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 20 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

TRIM6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Tripartite Motif Containing 6 (TRIM6) Interaction Partners

Human Tripartite Motif Containing 6 (TRIM6) interaction partners

  1. Intriguingly, the authors also found that TRIM6 enhances ebola virus polymerase activity in a minigenome assay and TRIM6 knockout cells have reduced replication of infectious ebola virus, suggesting that VP35 hijacks TRIM6 to promote ebola virus replication through ubiquitination.

  2. Live NiV infection, but not a recombinant NiV lacking the M protein, reduced the levels of endogenous TRIM6 protein expression. To our knowledge, matrix proteins of paramyxoviruses have never been reported to be involved in innate immune antagonism. We report here a novel mechanism of viral innate immune evasion by targeting TRIM6, IKKepsilon (show IKBKE Proteins) and unanchored polyubiquitin (show UBB Proteins) chains.

  3. TRIM6 and the E2-ubiquitin conjugase (show GGH Proteins) UbE2K (show UBE2K Proteins) cooperated in the synthesis of unanchored K48-linked polyubiquitin (show UBB Proteins) chains, which activated IKKepsilon (show IKBKE Proteins) for subsequent STAT1 (show STAT1 Proteins) phosphorylation.

  4. heterologous RING, B-box 2, and CC domains from related TRIM (show TRAT1 Proteins) proteins can functionally substitute for TRIM5alpha (show TRIM5 Proteins)(rh) domains.

Mouse (Murine) Tripartite Motif Containing 6 (TRIM6) interaction partners

  1. TRIM6 regulates the transcriptional activity of Myc (show MYC Proteins) during the maintenance of cell pluripotency, suggesting that TRIM6 functions as a novel regulator for Myc (show MYC Proteins)-mediated transcription in embryonic stem cells.

TRIM6 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members.

Gene names and symbols associated with TRIM6

  • tripartite motif containing 6 (TRIM6)
  • tripartite motif containing 6 (Trim6)
  • tripartite motif-containing 6 (Trim6)
  • C430046K18Rik protein
  • D7Ertd684e protein
  • DKFZP469D1621 protein
  • RNF89 protein
  • TRIM6 protein

Protein level used designations for TRIM6

tripartite motif-containing 6 , tripartite motif-containing 6, isoform 2 , tripartite motif-containing protein 6-like , tripartite motif-containing protein 6 , tripartite motif containing 6 , RING finger protein 89 , tripartite motif protein 6

100137558 Papio anubis
100174213 Pongo abelii
100392347 Callithrix jacchus
100568282 Pan troglodytes
100568303 Equus caballus
100587885 Nomascus leucogenys
117854 Homo sapiens
514492 Bos taurus
100328879 Oryctolagus cuniculus
293294 Rattus norvegicus
100568301 Canis lupus familiaris
94088 Mus musculus
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