anti-Troponin T2, Cardiac (TNNT2) Antibodies

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Additionally we are shipping Cardiac Troponin T2 Kits (97) and Cardiac Troponin T2 Proteins (33) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNNT2 7139 P45379
TNNT2 21956 P50752
TNNT2 24837 P50753
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Top anti-Cardiac Troponin T2 Antibodies at antibodies-online.com

Showing 10 out of 378 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Mouse PE ICS   50 Tests Log in to see 15 to 18 Days
$245.48
Details
Chicken Mouse Un-conjugated IHC (f), ICS, WB   0.1 mg Log in to see 15 to 18 Days
$325.09
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TNNT2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Muscle Host: Mouse Target Name: TNNT2 Sample Tissue: Mouse Skeletal Muscle Antibody Dilution: 1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of cTnT expression in H9 (A), 4T1 (B), human heart (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated EIA, WB TNNT2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNNT2 antibody detected the TNNT2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated IP, IHC, ELISA, WB   1 mg Log in to see 5 to 7 Days
$410.70
Details
Chicken Mouse Un-conjugated IF, IHC, IHC (p) Human Rabbit Heart (formalin-fixed, paraffin-embedded) stained with TNNT2 antibody ABIN462337 followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Anti-TNNT2 / CTnT antibody IHC of human rabbit heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. 50 μL Log in to see 11 to 14 Days
$484.00
Details
Cat Mouse Un-conjugated EIA, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$390.50
Details

Top referenced anti-Cardiac Troponin T2 Antibodies

  1. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody for ICS - ABIN2688864 : Jáchymová, Muravská, Paleček, Kuchynka, Řeháková, Magage, Kr��l, Zima, Horký, Linhart: Genetic variation screening of TNNT2 gene in a cohort of patients with hypertrophic and dilated cardiomyopathy. in Physiological research / Academia Scientiarum Bohemoslovaca 2012 (PubMed)
    Show all 7 Pubmed References

  2. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody for IHC (f), ICS - ABIN2688865 : Lian, Hsiao, Wilson, Zhu, Hazeltine, Azarin, Raval, Zhang, Kamp, Palecek: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 7 Pubmed References

  3. Human Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA - ABIN263478 : Feng, Taggart, Hall, Bryant, Sansone, Kemmerer, Herlich, Lord: Limited additional release of cardiac troponin I and T in isoproterenol-treated beagle dogs with cardiac injury. in Clinical chemistry 2005 (PubMed)
    Show all 6 Pubmed References

  4. Human Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA (Capture), ELISA - ABIN263480 : Goette, Arndt, Röcken, Staack, Bechtloff, Reinhold, Huth, Ansorge, Klein, Lendeckel: Calpains and cytokines in fibrillating human atria. in American journal of physiology. Heart and circulatory physiology 2002 (PubMed)
    Show all 6 Pubmed References

  5. Human Polyclonal Cardiac Troponin T2 Primary Antibody for IP, IHC - ABIN191343 : Hammerer-Lercher, Erlacher, Bittner, Korinthenberg, Skladal, Sorichter, Sperl, Puschendorf, Mair: Clinical and experimental results on cardiac troponin expression in Duchenne muscular dystrophy. in Clinical chemistry 2001 (PubMed)
    Show all 6 Pubmed References

  6. Cow (Bovine) Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA (Detection), ELISA - ABIN191346 : Nakaura, Morimoto, Yanaga, Nakata, Nishi, Imaizumi, Ohtsuki: Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy. in The American journal of physiology 1999 (PubMed)
    Show all 6 Pubmed References

  7. Human Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA - ABIN263477 : Urasawa, Wada, Machida, Yuasa, Shimatsu, Wakao, Yuasa, Sano, Nonaka, Nakamura, Takeda: Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71. in Circulation 2008 (PubMed)
    Show all 6 Pubmed References

  8. Mammalian Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA (Capture), ELISA - ABIN191341 : van den Berg, Abu-Issa, de Boer, Hutson, de Boer, Soufan, Ruijter, Kirby, van den Hoff, Moorman: A caudal proliferating growth center contributes to both poles of the forming heart tube. in Circulation research 2009 (PubMed)
    Show all 6 Pubmed References

More Antibodies against Cardiac Troponin T2 Interaction Partners

Human Troponin T2, Cardiac (TNNT2) interaction partners

  1. the optimal cutoff-value of hs-TnT to improve diagnostic accuracy of acute myocardial infarction in chronic kidney disease patients, was determined.

  2. The current results indicate that patients with nondipper hypertension (NDH) had higher high-sensitivity - cTnT levels than the patients with dipper hypertension. High-sensitivity -cTnT was an independent predictor of NDH and was significantly related with nondipping status.

  3. Studies indicate that in patients with end-stage renal disease (ESRD), elevation of cardiac-specific troponin T (cTnT) was more frequent than elevation of troponin I (cTnI) [Review].

  4. Data suggest that high sensitivity cardiac troponin (hs-cTnT) may help predict whether non-acute coronary syndrome (ACS) emergency department (ED) patients have a final non-ACS cardiac or non-cardiac/unknown origin diagnoses.

  5. Cardiac troponin T at the NMJ region contributes to NMJ functional decline with ageing mainly in the fast-twitch skeletal muscle through interfering with PKA signalling.

  6. On admission, high-sensitivity-troponin T/creatine kinase-MB ratio was significantly higher in takotsubo syndrome patients compared to myocardial infarction patients.

  7. Serum high-sensitivity cardiac troponin T (HS-cTnT) level is high and associated with carotid plaques in systemic lupus erythematous (SLE) patients.

  8. High sensitivity troponin T was detectable in over half of the congenitally corrected transposition of the great arteries population and was related to right ventricular function.

  9. In patients with perinatal asphyxia, the difference in troponin-T concentrations between moderate and severe encephalopathy was not statistically significant. Troponin-T concentration was significantly higher in babies with hypotensive shock and hepatic injury, but not acute kidney injury.

  10. Five of the 19 patients (26.3%) had either a pathogenic variant or a likely pathogenic variant in MYBPC3 (show MYBPC3 Antibodies) (n=1), MYH7 (show MYH7 Antibodies) (n=1), RYR2 (show RYR2 Antibodies) (n=2), or TNNT2 (n=1). All five variants were missense variants that have been reported previously in patients with channelopathies or cardiomyopathies

Mouse (Murine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Cardiac troponin T at the NMJ region contributes to NMJ functional decline with ageing mainly in the fast-twitch skeletal muscle through interfering with PKA signalling.

  2. Hypertrophic cardiomyopathy pathophysiology is "mutation specific" in mice models carrying TNNT2 E163R and R92Q mutations.

  3. TnTA30V mutation attenuated Ca(2 (show CA2 Antibodies)+)-activated maximal tension and length-mediated cross-bridge recruitment against alpha-myosin (show MYH6 Antibodies) heavy chain but augmented these parameters against beta-myosin heavy chain (show MYH7 Antibodies), suggesting divergent contractile phenotypes.

  4. The shift from cTnT exon 5 inclusion to exclusion during development was delayed in the heart of Ts65Dn mice due to Dyrk1A (show DYRK1A Antibodies) overexpression.

  5. for hypertrophic cardiomyopathy (HCM)-causing mutations in TnT (show TNNI1 Antibodies), Ca(2 (show CA2 Antibodies)+)-sensitisation together with uncoupling in vitro is the usual response and both factors may contribute to the HCM phenotype

  6. cardiomyopathy mutation (R97L) in mouse cardiac troponin T has an effect on the muscle length-mediated recruitment of crossbridges and is modified divergently by alpha- and beta-myosin heavy chain (show MYH7 Antibodies)

  7. Data indicate that high-sensitivity troponin T (hs-TnT) levels are influenced by myocardial dysfunction/heart failure (HF) in acute exacerbation of chronic obstructive lung disease (AECOPD), but provide independent prognostic information.

  8. cTnT elevation emerged as a strong, independent predictor of 30-day mortality and remained a modest, but significant, predictor throughout 2 years post transcatheter aortic valve implantation.

  9. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  10. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

Zebrafish Troponin T2, Cardiac (TNNT2) interaction partners

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1 (show TNNI1 Antibodies), Tnnt2, and Tnnt3b were conserved in the central tropomyosin (show TPM2 Antibodies)- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 (show TNNI1 Antibodies) and Tnnt2, but not Tnnt3b.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Significant changes in thin filament Ca2 (show CA2 Antibodies)+-sensitivity, structure and kinetics are brought about through PKC phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Rabbit Troponin T2, Cardiac (TNNT2) interaction partners

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Cardiac Troponin T2 (TNNT2) Antigen Profile

Protein Summary

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Gene names and symbols associated with TNNT2

  • troponin T2, cardiac type (TNNT2) antibody
  • troponin T2, cardiac (Tnnt2) antibody
  • troponin T2, cardiac type (Tnnt2) antibody
  • troponin T type 2a (cardiac) (tnnt2a) antibody
  • troponin T2, cardiac type L homeolog (tnnt2.L) antibody
  • troponin T2e, cardiac (tnnt2e) antibody
  • CMH2 antibody
  • CMPD2 antibody
  • CT3 antibody
  • cTnT antibody
  • Ctt antibody
  • CTTG antibody
  • LVNC6 antibody
  • RATCTTG antibody
  • RCM3 antibody
  • si:ch211-136g2.1 antibody
  • tnnt2 antibody
  • Tnnt3 antibody
  • Tnt antibody
  • TnTC antibody

Protein level used designations for TNNT2

cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , troponin T, cardiac muscle , troponin T2, cardiac , cardiac TnT , cardiac muscle troponin T , tnTc , Troponin T cardiac , cTnT , cardiac troponin T2 , sih , silent heart , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , cardiac troponin T , troponin T type 2, cardiac , cardiac troponin 2 , Troponin T, cardiac muscle , troponin T cardiac isoform , novel slow skeletal troponin T family protein , troponin T2e, cardiac

GENE ID SPECIES
7139 Homo sapiens
21956 Mus musculus
24837 Rattus norvegicus
58071 Danio rerio
286816 Bos taurus
396433 Gallus gallus
403532 Canis lupus familiaris
493940 Felis catus
100379561 Cavia porcellus
398518 Xenopus laevis
100622450 Sus scrofa
100009428 Oryctolagus cuniculus
556703 Danio rerio
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