Cardiac Troponin T2 antibody

Catalog No. ABIN969445

Product Details anti-Cardiac Troponin T2 Antibody

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cardiac Troponin T2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human troponin T2 expressed in E. coli.

Clone: 1G1

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-Cardiac Troponin T2 antibody (ABIN969445)

Luedde, Ehlermann, Weichenhan, Will, Zeller, Rupp, Müller, Steen, Ivandic, Ulmer, Kern, Katus, Frey: "Severe familial left ventricular non-compaction cardiomyopathy due to a novel troponin T (TNNT2) mutation." in: Cardiovascular research, Vol. 86, Issue 3, pp. 452-60, (2010) (PubMed).

Target Details for Cardiac Troponin T2

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Abstract: cTnT Products

Synonyms: CMH2 antibody, CMPD2 antibody, LVNC6 antibody, RCM3 antibody, TnTC antibody, cTnT antibody, Tnt antibody, CTTG antibody, Ctt antibody, RATCTTG antibody, Tnnt3 antibody, tnnt2 antibody, CT3 antibody, si:ch211-136g2.1 antibody, troponin T2, cardiac type antibody, troponin T2, cardiac antibody, troponin T type 2a (cardiac) antibody, troponin T2, cardiac type L homeolog antibody, troponin T2e, cardiac antibody, TNNT2 antibody, Tnnt2 antibody, tnnt2a antibody, tnnt2.L antibody, tnnt2e antibody

Background:

Description: The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Aliases: CMH2, RCM3, TnTC, cTnT, CMPD2, LVNC6

Molecular Weight: 36 kDa

Gene ID: 7139

HGNC: 7139