Tryptophan 2,3-Dioxygenase (TDO2) ELISA Kits

TDO2 encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Additionally we are shipping Tryptophan 2,3-Dioxygenase Antibodies (63) and Tryptophan 2,3-Dioxygenase Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TDO2 6999 P48775
TDO2 56720 P48776
TDO2 64206 P21643
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Top Tryptophan 2,3-Dioxygenase ELISA Kits at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
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Mouse 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Rat 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Rabbit 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Monkey 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Cow
  96 Tests Log in to see 15 to 18 Days
$707.14
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Chicken
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$707.14
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More ELISA Kits for Tryptophan 2,3-Dioxygenase Interaction Partners

Human Tryptophan 2,3-Dioxygenase (TDO2) interaction partners

  1. TDO2 overexpression was related to poor prognosis and associated with cancer cell proliferation and tumor stem cells in esophageal squamous cell carcinoma.

  2. Study demonstrated that n-butylidenephthalide (n-BP)functions by regulating the early part of the kynurenine pathway through the downregulation of tryptophan 2, 3-dioxygenase (TDO2), which decreases the downstream neurotoxic product, quinolinic acid (QA). Findings indicate a correlation between n-BP, TDO2, QA, calpain, and toxic fragment formation.

  3. the potent antimicrobial as well as immunoregulatory effects of TDO (show DLX3 ELISA Kits) were substantially impaired under hypoxic conditions that pathophysiologically occur in vivo. This might be detrimental for the appropriate host immune response towards relevant pathogens.

  4. High TDO2 expression is associated with Colorectal Cancer.

  5. Crystal tryptophan 2,3-dioxygenase structure revealed eight residues playing critical roles in L-tryptophan oxidation.

  6. IL-1beta (show IL1B ELISA Kits) is suggested to stimulate tryptophan catabolism and production of IL-6 (show IL6 ELISA Kits) and IL-8 (show IL8 ELISA Kits) by increasing TDO (show DLX3 ELISA Kits) expression in endometriosis.

  7. Identification of 12 polymorphisms in the human TDO2 promoter region, 2 of them corresponding to previously unknown single-nucleotide polymorphisms and 3 of them located in putative glucocorticoid-responsive elements.

  8. TDO (show DLX3 ELISA Kits) is highly expressed in the brains of Alzheimer disease patients.

  9. The data suggest that TDO (show DLX3 ELISA Kits) uses a ring-opening mechanism during N-formylkynurenine formation, rather than Criegee or dioxetane mechanisms as previously proposed.

  10. subtle differences between the TDO (show DLX3 ELISA Kits) and IDO (show IDO1 ELISA Kits) reactions

Mouse (Murine) Tryptophan 2,3-Dioxygenase (TDO2) interaction partners

  1. TDO-deficiency protected from neuronal loss in the spinal cord but not in the optic nerves.

  2. Study demonstrated that n-butylidenephthalide (n-BP)functions by regulating the early part of the kynurenine pathway through the downregulation of tryptophan 2, 3-dioxygenase (TDO2), which decreases the downstream neurotoxic product, quinolinic acid (QA). Findings indicate a correlation between n-BP, TDO2, QA, calpain, and toxic fragment formation.

  3. Data suggest that Indoleamine 2,3-dioxygenase 1 (IDO1 (show IDO1 ELISA Kits)) appears to be a potential hallmark of liver lesions, and its deficiency protects mice from CCl4 (show CCL4 ELISA Kits)-induced fibrosis mediated by Th17 cells down-regulation and tryptophan 2,3-dioxygenase (TDO) compensatory increase.

  4. Findings suggest non-redundant neurophysiological roles for indoleamine 2,3-dioxygenase 1 (show IDO1 ELISA Kits), indoleamine 2,3-dioxygenase 2 (show IDO2 ELISA Kits) and tryptophan 2,3-dioxygenase in modulating brain activities and metabolism.

  5. Data suggest that high-fat diet (HFD) alters regulation of expression of sirtuins (Sirt4 (show SIRT4 ELISA Kits) and Sirt7 (show SIRT7 ELISA Kits)) and enzymes in NAD biosynthetic pathway (Tdo2 and Nnmt (show NNMT ELISA Kits)); these alterations are more prominent in liver as compared to white adipose tissue or skeletal muscle; Tdo2 and Nnmt (show NNMT ELISA Kits) may serve as markers of HFD consumption. (Tdo2 = tryptophan 2,3-dioxygenase; Nnmt (show NNMT ELISA Kits) = nicotinamide N-methyltransferase (show NNMT ELISA Kits))

  6. both TDO and IDO (show IDO1 ELISA Kits) biosynthesize nicotinamide from D-tryptophan and L-tryptophan in mice

  7. Data indicate that tryptophan 2,3-dioxygenase (Tdo2) may play an important role during mouse decidualization and be regulated by estrogen, progesterone, and cAMP.

  8. These findings demonstrate a direct molecular link between Trp metabolism and neurogenesis and anxiety-related behavior under physiological conditions.

  9. Endometrial expression of TDO in epithelial and stromal cells is regulated by HOXA10 (show HOXA10 ELISA Kits). Expression level of TDO influences infiltration of T-cells into endometrial stroma and thus may influence embryo viability.

  10. These findings indicate that TDO might be required at a late-stage of granule cell development, such as during axonal and dendritic growth, synaptogenesis and its maturation.

Tryptophan 2,3-Dioxygenase (TDO2) Antigen Profile

Antigen Summary

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

Gene names and symbols associated with TDO2

  • tryptophan 2,3-dioxygenase b (tdo2b) antibody
  • tryptophan 2,3-dioxygenase (tdo2) antibody
  • tryptophan 2,3-dioxygenase (TDO2) antibody
  • tryptophan 2,3-dioxygenase (MADE_02822) antibody
  • tryptophan 2,3-dioxygenase (CtCNB1_3657) antibody
  • tryptophan 2,3-dioxygenase a (tdo2a) antibody
  • tryptophan 2,3-dioxygenase (CNC04830) antibody
  • tryptophan 2,3-dioxygenase (tdo) antibody
  • tryptophan 2,3-dioxygenase (Mrub_2119) antibody
  • tryptophan 2,3-dioxygenase (Deipr_2235) antibody
  • tryptophan 2,3-dioxygenase (Acav_1166) antibody
  • tryptophan 2,3-dioxygenase (Mesop_4278) antibody
  • tryptophan 2,3-dioxygenase (Tdo2) antibody
  • tryptophan 2,3-dioxygenase L homeolog (tdo2.L) antibody
  • AA407491 antibody
  • chky antibody
  • DDBDRAFT_0190495 antibody
  • DDBDRAFT_0231363 antibody
  • DDB_0190495 antibody
  • DDB_0231363 antibody
  • fb62b10 antibody
  • fi30d08 antibody
  • Tdo antibody
  • tdo2 antibody
  • tdo2l antibody
  • TO antibody
  • TPH2 antibody
  • TRPO antibody
  • wu:fb62b10 antibody
  • wu:fi30d08 antibody
  • zgc:63488 antibody
  • zgc:103693 antibody

Protein level used designations for TDO2

TDO-B , TO-B , TRPO-B , tryptamin 2,3-dioxygenase B , tryptophan 2,3-dioxygenase B , tryptophan 2,3-dioxygenase, like , tryptophan oxygenase B , tryptophan pyrrolase B , tryptophanase B , TDO , TO , TRPO , tryptamin 2,3-dioxygenase , tryptophan oxygenase , tryptophan pyrrolase , tryptophanase , tryptophan 2,3-dioxygenase , TDO-A , TO-A , TRPO-A , tryptamin 2,3-dioxygenase A , tryptophan 2,3-dioxygenase A , tryptophan oxygenase A , tryptophan pyrrolase A , tryptophanase A , tdo variant1 , tdo variant2 , tryptophan-2,3-dioxygenase , tryptophan-23-dioxygenase

GENE ID SPECIES
334082 Danio rerio
548450 Xenopus (Silurana) tropicalis
699739 Macaca mulatta
736252 Pan troglodytes
4456236 Ralstonia eutropha H16
4649802 Gramella forsetii KT0803
6776077 Alteromonas macleodii 'Deep ecotype'
8562285 Comamonas testosteroni CNB-2
100008541 Danio rerio
3256592 Cryptococcus neoformans var. neoformans JEC21
8617171 Dictyostelium discoideum AX4
8880228 Meiothermus ruber DSM 1279
10265555 Deinococcus proteolyticus MRP
10306071 Acidovorax avenae subsp. avenae ATCC 19860
10828127 Mesorhizobium opportunistum WSM2075
6999 Homo sapiens
475476 Canis lupus familiaris
56720 Mus musculus
64206 Rattus norvegicus
530397 Bos taurus
100344083 Oryctolagus cuniculus
100727713 Cavia porcellus
100301559 Sus scrofa
422409 Gallus gallus
495495 Xenopus laevis
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