anti-Tudor Domain Containing 3 (TDRD3) Antibodies

Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Additionally we are shipping TDRD3 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TDRD3 81550 Q9H7E2
TDRD3 219249 Q91W18
TDRD3 306066 Q66HC1
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Top anti-TDRD3 Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC (p), WB   100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IF, IP, WB Western blot analysis of extracts of U2OS cells, using TDRD3 antibody (ABIN1877029) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s. 100 μL Log in to see 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of U2OS cells, using TDRD3 antibody (ABIN5973573) at 1/1000 dilution. 100 μL Log in to see 11 to 16 Days
$412.19
Details
Human Mouse Un-conjugated WB Western Blot analysis of TDRD3 expression in transfected 293T cell line by TDRD3 MaxPab polyclonal antibody.Lane 1: TDRD3 transfected lysate(71.61 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated IP   100 μg Log in to see 11 to 14 Days
$595.83
Details
Human Rabbit Un-conjugated IP   100 μL Log in to see 11 to 14 Days
$595.83
Details
Chicken Rabbit Un-conjugated IF, IHC, IHC (p), IP, WB   100 μL Log in to see 11 to 14 Days
$595.83
Details
Chicken Rabbit Un-conjugated IF, IHC, IHC (p)   100 μL Log in to see 11 to 14 Days
$625.17
Details
Human Rabbit Un-conjugated IF, IP, WB   100 μL Log in to see 11 to 16 Days
$743.29
Details
Human Rabbit Biotin ELISA   100 μg Log in to see 11 to 16 Days
$412.19
Details

More Antibodies against TDRD3 Interaction Partners

Human Tudor Domain Containing 3 (TDRD3) interaction partners

  1. Our work depicts the structural plasticity of the TDRD3 Tudor domain and paves the way for the subsequent structure-guided discovery of selective inhibitors targeting Tudor domains

  2. Study reports TDRD3 as a novel regulator of cell proliferation and invasion in breast cancer cells. Its depletion inhibits tumor formation and metastasis to the lung in vivo. Furthermore, TDRD3 regulates the expression of a number of key genes associated with promotion of breast cancer tumorigenesis and disease progression at the level of translation.

  3. Structural basis of the interaction between TOP3B and the TDRD3 auxiliary factor has been reported.

  4. Top3b proteins from several animals associate with polyribosomes, which are units of mRNA translation, whereas the Top3 homologs from E. coli and yeast lack the association. The Top3b-polyribosome association requires TDRD3, which directly interacts with Top3beta and is present in animals but not bacteria or yeast.

  5. The binding specificity and affinity of the Tudor domains of TDRD3, SMN and SPF30 proteins were characterized quantitatively.

  6. The TDRD3 is an effector molecule that promotes transcription by binding methylarginine marks on histone tails.

  7. Tudor domain of TDRD3 was required for its recruitment to cytoplasmic stress granules.

  8. propose a contribution of Tdrd3 to FMRP-mediated translational repression and suggest that the loss of the FMRP-Tdrd3 interaction caused by the I304N mutation might contribute to the pathogenesis of Fragile X syndrome

TDRD3 Antigen Profile

Protein Summary

Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine- methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins (By similarity).

Gene names and symbols associated with TDRD3

  • tudor domain containing 3 (TDRD3) antibody
  • tudor domain containing 3 (Tdrd3) antibody
  • tudor domain containing 3 (tdrd3) antibody
  • tudor domain containing 3 L homeolog (tdrd3.L) antibody
  • 4732418C03Rik antibody
  • 6720468N18 antibody
  • zgc:77174 antibody

Protein level used designations for TDRD3

tudor domain containing 3 , tudor domain-containing protein 3

GENE ID SPECIES
100217625 Taeniopygia guttata
81550 Homo sapiens
219249 Mus musculus
306066 Rattus norvegicus
537918 Bos taurus
418823 Gallus gallus
402828 Danio rerio
431810 Xenopus laevis
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