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TDRD7 encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs. Additionally we are shipping TDRD7 Antibodies (27) and many more products for this protein.
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Human cataracts and the TDRD7 gene loss-of-function mutations are strongly causally related, as the expression level of plasma TDRD7 mRNA in patients with cataracts was statistically significantly lower than in the normal control group.
present study suggests that the rs10981985 G --> A variant within the TDRD7 gene may protect against cortical age-related cataract in a Han Chinese population
study describes 2 cases of pediatric cataract with loss-of-function mutations in TDRD7; TDRD7 coimmunoprecipitates with specific lens mRNAs; required for posttranscriptional control of mRNAs critical to normal lens development and RNA granule function
results identify TRPC3 as a pivotal signaling gateway in Ca(2+)-dependent control of cardiac gene expression
Tdrd7 nullizygosity causes cataract and glaucoma and arrest in spermatogenesis;TDRD7 coimmunoprecipitates with specific lens mRNAs; required for posttranscriptional control of mRNAs critical to normal lens development and RNA granule function
Tudor-related proteins, which contain multiple repeats of the Tudor domain, constitute an evolutionarily conserved class of nuage components in the germ-line, and their localization or accumulation to nuage is likely conferred by a Tudor domain structure
This gene encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs. Mutation in this gene has been associated with pediatric cataracts. Mutation of the similar gene in mice has been associated with cataracts, glaucoma and a block in spermatogenesis.
, tudor domain-containing protein 7
, tudor repeat associator with PCTAIRE 2
, tudor repeat associator with PCTAIRE-2
, tudor domain-containing protein 7A