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Involved in the mineralization and structural organization of enamel.. Additionally we are shipping TUFT1 Antibodies (37) and TUFT1 Kits (5) and many more products for this protein.
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TUFT1 may affect HIF1 (show HIF1A Proteins)-Snail (show SNAI1 Proteins) signaling in pancreatic neoplasms, regulating epithelial mesenchymal transition and metastasis.
A nonsynonymous single nucleotide variant rs41310883 in TUFT1 plays a role in chondrocyte differentiation and cartilage mineralization apparently on a calcium-related pathway, and thus can be considered as a novel susceptibility gene metatarsophalangeal osteoarthritis.
the statistically significant association of rs2337359 upstream of TUFT1 with dental caries experience via meta-analysis across adult samples (p < 0.002) and the suggestive association for multiple variants in TFIP11 (show TFIP11 Proteins) across child samples
We found evidence for a trend of association between genetic variation of TUFT1 and TFIP11 (show TFIP11 Proteins) and MIH, which suggest these genes are potentially involved in individual predisposition to MIH.
Human tuftelin gene contains 13 exons and is larger than 26 kb, with two alternatively spliced tuftelin mRNA transcripts now been identified in the human tooth bud.
The human tuftelin gene and the expression of tuftelin in mineralizing and nonmineralizing tissues. Review.
The CT genotype of the tuftelin rs3790506 marker was overrepresented in cases with dmft scores higher than 5 and dmfs scores higher than 6 compared to controls.
These data raise the hypothesis that enamelin (show ENAM Proteins) defects have pleiotropic effects on organs other than the teeth.
The pathways affecting the expression of tuftelin in PC12 cells and mice are described.
Involved in the mineralization and structural organization of enamel.