Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) ELISA Kits

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies (173) and Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins (36) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 18383 O08712
TNFRSF11B 25341 O08727
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Top Tumor Necrosis Factor Receptor Superfamily, Member 11b ELISA Kits at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 31.25 pg/mL 125-8000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$865.33
Details
Human 5pg/mL 93.7-6000 pg/mL Human OPG PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$320.00
Details
Mouse 1 pg/mL 1-1200 pg/mL 96 Tests Log in to see 2 to 3 Days
$480.70
Details
Chicken 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$576.00
Details
Rabbit 0.78 pg/mL 3.12-200 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$865.33
Details
Pig 0.061 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$968.71
Details
Cow 0.16 ng/mL   96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Monkey 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$616.00
Details

Top referenced Tumor Necrosis Factor Receptor Superfamily, Member 11b ELISA Kits

  1. Human TNFRSF11B ELISA Kit for Sandwich ELISA - ABIN625067 : Lacey, Timms, Tan, Kelley, Dunstan, Burgess, Elliott, Colombero, Elliott, Scully, Hsu, Sullivan, Hawkins, Davy, Capparelli, Eli, Qian, Kaufman, Sarosi, Shalhoub, Senaldi, Guo, Delaney, Boyle: Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. in Cell 1998 (PubMed)
    Show all 35 Pubmed References

  2. Human TNFRSF11B ELISA Kit for Sandwich ELISA - ABIN365396 : Clérigues, Guillén, Castejón, Gomar, Mirabet, Alcaraz: Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1? in osteoarthritic osteoblasts. in Biochemical pharmacology 2011 (PubMed)
    Show all 8 Pubmed References

  3. Mouse (Murine) TNFRSF11B ELISA Kit for Sandwich ELISA - ABIN411342 : Li, Feng, Zhu, Li, Luo, Hu: Osteogenesis response to implanted materials in endocortical bone in rat femora. in Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2012 (PubMed)
    Show all 12 Pubmed References

  4. Mouse (Murine) TNFRSF11B ELISA Kit for Sandwich ELISA - ABIN625170 : Hartwich, Orr, Ng, Spence, McLaughlin, Furman, McGregor, Davidoff: Rapamycin increases neuroblastoma xenograft and host stromal derived osteoprotegerin inhibiting osteolytic bone disease in a bone metastasis model. in Journal of pediatric surgery 2013 (PubMed)
    Show all 7 Pubmed References

  5. Human TNFRSF11B ELISA Kit for Sandwich ELISA - ABIN411341 : Chen, Li, Liu, Wang, Xie, Liu, Hou, Chang, Du: Canonical Wnt signaling is required for Panax notoginseng saponin-mediated attenuation of the RANKL/OPG ratio in bone marrow stromal cells during osteogenic differentiation. in Phytomedicine : international journal of phytotherapy and phytopharmacology 2012 (PubMed)
    Show all 10 Pubmed References

  6. Mouse (Murine) TNFRSF11B ELISA Kit for Sandwich ELISA - ABIN2685709 : Ohmori, Makita, Funamizu, Hirooka, Hosoi, Orimo, Suzuki, Ikari, Nakajima, Inoue, Hata: Linkage and association analyses of the osteoprotegerin gene locus with human osteoporosis. in Journal of human genetics 2002 (PubMed)
    Show all 4 Pubmed References

  7. Rat (Rattus) TNFRSF11B ELISA Kit for Sandwich ELISA - ABIN456064 : Che, Bing, Akhtar, Tingting, Kezhou, Rong: Lanthanum carbonate prevents accelerated medial calcification in uremic rats: role of osteoclast-like activity. in Journal of translational medicine 2013 (PubMed)

  8. Human TNFRSF11B ELISA Kit for Sandwich ELISA - ABIN512280 : Qiao, Shui, Cai, Guo, Jiang: Human mesenchymal stem cells as delivery of osteoprotegerin gene: homing and therapeutic effect for osteosarcoma. in Drug design, development and therapy 2015 (PubMed)

More ELISA Kits for Tumor Necrosis Factor Receptor Superfamily, Member 11b Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. OPG has a role in cancer progression, especially breast cancer [review]

  2. OPG rs2073618 polymorphism could be a possible genetic marker for the prediction of increased risk for carotid plaque burden as a measure of advanced subclinical atherosclerosis in T2DM subjects.

  3. The compound with greatest potential is E05657 with high activity and low effective concentration in the HTS (show APCDD1 ELISA Kits) system. It increases the OPG/RANKL (show TNFSF11 ELISA Kits) ratio and OPG secretion, decreases the NFATc1 (show NFATC1 ELISA Kits) expression, and reduces osteoclastogenesis in vitro

  4. OPG T950C polymorphism might be associated with an increased osteoporosis risk in the Chinese population

  5. We have concluded that low OPG levels may be associated with osteoporosis in ulcerative colitis, but it is not correlated with the c.-223C > T polymorphism in the TNFRSF11B gene.

  6. RANKL (show TNFSF11 ELISA Kits)/Osteoprotegerin have roles in bone turnover in Hashimoto Thyroiditis

  7. High OPG expression is associated with colorectal carcinoma.

  8. Data suggest that elevated plasma levels of osteoprotegerin/TNFRSF11B correlate with increased risk of cardiovascular comorbidities in children and adolescents with type 1 diabetes (as compared to healthy control subjects); thus, osteoprotegerin/TNFRSF11B may serve as biomarker of cardiovascular risk in these patients. This study was conducted in Tunisia.

  9. Studies showed that the central hypothalamic-pituitary regulatory system, via it's relative hormones, seems to control OPG/RANKL (show TNFSF11 ELISA Kits)/RANK system function, and the pulsatility and circadian rhythmicity of these hormones may induce an oscillatory fluctuation of the OPG/ RANKL (show TNFSF11 ELISA Kits) ratio. Also, psycological characteristics may provoke a shift of the OPG/ RANKL (show TNFSF11 ELISA Kits) ratio towards an unbalanced or a balanced status. [review]

  10. Formulation and in vitro and in vivo evaluation of a new osteoprotegerin-chitosan gel for bone tissue regeneration

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. findings demonstrate that mTORC1 activation-stimulated RANKL (show TNFSF11 ELISA Kits) expression in B cells is sufficient to induce bone loss and osteoporosis. The study also established a link between mTORC1 and the RANKL/OPG (show TNFSF11 ELISA Kits) axis via negative regulation of beta-catenin (show CTNNB1 ELISA Kits).

  2. RANK/RANKL (show TNFSF11 ELISA Kits) signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin to prevent bone metastasis.

  3. endocortical resorption is driven by reduced OPG (show TNFSF11 ELISA Kits) rather than elevated RANKL (show TNFSF11 ELISA Kits) expression

  4. Diabetes significantly increased OPG (show TNFSF11 ELISA Kits) and the OPG (show TNFSF11 ELISA Kits)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (show TNFSF11 ELISA Kits) and reduced TRAIL expression, thus increasing cardiac OPG (show TNFSF11 ELISA Kits)/TRAIL ratio.

  5. These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (show TNFSF11 ELISA Kits) interaction and osteoclastogenesis.

  6. OPG (show TNFSF11 ELISA Kits) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  7. These data suggested that OPG (show TNFSF11 ELISA Kits) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  8. Data show that p38alpha (show MAPK14 ELISA Kits) mitogen-activated protein kinase (show MAPK1 ELISA Kits) (MAPK (show MAPK1 ELISA Kits)) in paired related homeobox 1 (show PRRX1 ELISA Kits) protein (Prx1 (show PRDX1 ELISA Kits)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  9. OPG (show TNFSF11 ELISA Kits) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  10. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. The OPG (show TNFSF11 ELISA Kits) expression levels decreased while those of RANKL (show TNFSF11 ELISA Kits) and RUNX2 (show RUNX2 ELISA Kits) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 ELISA Kits) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Gene names and symbols associated with TNFRSF11B

  • TNF receptor superfamily member 11b (TNFRSF11B) antibody
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) antibody
  • TNF receptor superfamily member 11B (Tnfrsf11b) antibody
  • tumor necrosis factor receptor superfamily member 11b S homeolog (tnfrsf11b.S) antibody
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) antibody
  • ocif antibody
  • opg antibody
  • tr1 antibody

Protein level used designations for TNFRSF11B

osteoclastogenesis inhibitory factor , osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like

GENE ID SPECIES
4982 Homo sapiens
18383 Mus musculus
25341 Rattus norvegicus
464351 Pan troglodytes
523822 Bos taurus
100037695 Ovis aries
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100348133 Oryctolagus cuniculus
100049688 Sus scrofa
100860896 Capra hircus
100065885 Equus caballus
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