anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Antibodies

This intronless gene encodes a carcinoma-associated antigen. Additionally we are shipping TACSTD2 Proteins (26) and TACSTD2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TACSTD2 4070 P09758
TACSTD2 56753 Q8BGV3
TACSTD2 494343 Q6P9Z6
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Top anti-TACSTD2 Antibodies at antibodies-online.com

Showing 10 out of 151 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, IHC, WB ABIN308423 (0.2 ug/ml) staining of Human Prostate lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Human Mouse Un-conjugated IF, IF/ICC, IHC (p) Immunofluorescence staining of human TROP2 in MCF-7 cells with mouse monoclonal antibody (15 µg/mL). The image showing membrane staining of MCF-7 cells. Immunochemical staining of human TROP2 in human placenta with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of cytotrophoblast. 100 μL 14 to 16 Days
$247.82
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of TACSTD2 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of TACSTD2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from A549/NIH-3T3 cells, using TACD2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Bat Goat Un-conjugated ELISA, IHC, IHC (p), WB Anti-TROP2 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962687 concentration 41396 ug/ml. Anti-TROP2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Mouse Un-conjugated ELISA, ELISA (Detection), FACS, IHC (p) Immunochemical staining of human TROP2 in human placenta with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of cytotrophoblast. Immunochemical staining of human TROP2 in human mammary gland with mouse monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of alveolus epithelium. 100 μL 14 to 16 Days
$247.82
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Available
$363.46
Details
Human Mouse FITC FACS, IF, IF/ICC Immunofluorescence staining of Human TROP2 in MCF7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Mouse anti-Human TROP2 monoclonal antibody (FITC-conjugated, 10 µg/ml) at 37℃ 1 hour. Positive staining was localized to pla Flow cytometric analysis of anti-human TROP2 on MCF-7 cells. MCF-7 cells were detached using 1X trypsin, washed, then stained with FITC Mouse anti-human TROP2. 100 Tests 14 to 16 Days
$365.59
Details
Human Rabbit Un-conjugated ELISA, FACS, IF, IF/ICC Immunofluorescence staining of human TROP2 in MCF-7 cells with rabbit monoclonal antibody (5 µg/mL). The image showing membrane staining of MCF-7 cells. 100 μL 14 to 16 Days
$312.53
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Immunochemical staining of human TROP2 in human mammary gland with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of alveolus epithelium. Immunochemical staining of human TROP2 in human rectal cancer with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections). 100 μL 14 to 16 Days
$312.53
Details

Top referenced anti-TACSTD2 Antibodies

  1. Human Polyclonal TACSTD2 Primary Antibody for CyTOF, FACS - ABIN4900496 : Ambrogi, Fornili, Boracchi, Trerotola, Relli, Simeone, La Sorda, Lattanzio, Querzoli, Pedriali, Piantelli, Biganzoli, Alberti: Trop-2 is a determinant of breast cancer survival. in PLoS ONE 2014 (PubMed)
    Show all 12 Pubmed References

  2. Mouse (Murine) Polyclonal TACSTD2 Primary Antibody for CyTOF, FACS - ABIN4900492 : Eisenwort, Jurkin, Yasmin, Bauer, Gesslbauer, Strobl: Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-?1-dependent human epidermal Langerhans cells. in The Journal of investigative dermatology 2011 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal TACSTD2 Primary Antibody for FACS, IHC - ABIN2689944 : Bobos, Kotoula, Kaloutsi, Karayannopoulou, Papadimitriou, Kostopoulos: Aberrant CCND1 copies and cyclin D1 mRNA expression do not result in the production of functional cyclin D1 protein in anaplastic large cell lymphoma. in Histology and histopathology 2009 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal TACSTD2 Primary Antibody for CyTOF, FACS - ABIN4900015 : Yamaguchi, Nishii, Nakamura, Aoki, Hirai, Uchida, Sakuma, Hamada: Development of a sensitive screening method for selecting monoclonal antibodies to be internalized by cells. in Biochemical and biophysical research communications 2016 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal TACSTD2 Primary Antibody for FACS - ABIN4897042 : Hussain, Lawrence, Taylor, Lo, Frydenberg, Ellem, Furic, Risbridger: Estrogen receptor β activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations. in PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

  6. Polyclonal TACSTD2 Primary Antibody for ELISA, WB - ABIN539654 : Shimada, Kano, Ishiyama, Okubo, Iijima, Morishita, Minami, Inadome, Shu, Sugita, Takeuchi, Noguchi: Establishment of an immortalized cell line from a precancerous lesion of lung adenocarcinoma, and genes highly expressed in the early stages of lung adenocarcinoma development. in Cancer science 2005 (PubMed)

  7. Human Polyclonal TACSTD2 Primary Antibody for IF (p) - ABIN918712 : Zhou, Copeland, Otto-Duessel, He, Markel, Synold, Jones: Low Testosterone Alters the Activity of Mouse Prostate Stem Cells. in The Prostate 2016 (PubMed)

  8. Mouse (Murine) Polyclonal TACSTD2 Primary Antibody for FACS - ABIN4897798 : Stoyanova, Goldstein, Cai, Drake, Huang, Witte: Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling. in Genes & development 2012 (PubMed)

More Antibodies against TACSTD2 Interaction Partners

Human Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) interaction partners

  1. TROP-2 can be considered a useful marker for distinguishing papillary thyroid carcinoma follicular variant cases from follicular nodular disease and follicular adenoma cases because of its high sensitivity in the identification of papillary carcinomas of the thyroid.

  2. Study demonstrated that TROP2 expression was increased in glioblastoma tissues and glioblastoma cell lines. High TROP2 expression was significantly correlated with the poor survival of glioblastoma patients.

  3. The results suggest that TROP2 expression could be an effective prognostic biomarker for oral squamous cell carcinoma

  4. TROP-2, SLP-2 and CD56 were effective diagnostic markers for PTC, especially when they were combined to use.

  5. Trop2 has a potential role in the promotion of EMT in BC.

  6. these results suggested that TROP2 may promote osteosarcoma cell proliferation and migration via PI3K/AKT signaling and may serve as a novel treatment target for osteosarcoma .

  7. TACSTD2 downregulation is associated with hepatocellular carcinoma.

  8. findings demonstrate that a membranous TROP-2 staining pattern is highly specific for PTC, which may serve as a potential diagnostic marker aiding in the accurate classification of morphologically equivocal thyroid follicular-patterned lesions

  9. TROP2 promoted the proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT.

  10. The results from clinical specimens showed that Trop2 expression correlated with MMP2 expression in primary thyroid cancer. The current study suggests that elevated expression of Trop2 may represent an important molecular hallmark that is biologically and clinically relevant to the progression of thyroid cancer.

  11. these results suggest a differential role for TROP2 in different lung cancer subtypes

  12. Results show that TROP2 expression is up-regulated in gastric tumor and its co-expression with AREG protein is associated with TNM stage, tumor size, lymph node metastases, and distant metastases.

  13. Our findings indicate that the expression of Trop-2 is a stringent predictor of tumor response to AKT inhibitors. They also support the identification of target-activatory pathways, as efficient predictors of response in precision cancer therapy.

  14. Findings suggest that high TROP2 expression identifies distinct cell sub-populations in androgen-sensitive and androgen-independent prostate tumors and that it may be a predictive biomarker for prostate cancer treatment response in androgen-sensitive tumors.

  15. TROP2 may play a crucial role in COPD by affecting basal cells function and thus airway remodeling through increased basal cells hyperplasia

  16. TROP2 was overexpressed specifically in the majority of epithelial ovarian cancer and may be a novel prognostic biomarker

  17. we compared the diagnostic value of TROP-2 expression in distinguishing between benign and malignant thyroid lesions to those of HBME-1, CK19 and galectin-3

  18. TROP-2 membranous staining is a very sensitive and specific marker for the classic and tall cell variants of papillary thyroid carcinoma, and for papillary microcarcinomas , with high overall specificity for papillary thyroid carcinoma

  19. The results suggested that trop2 facilitated neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway.

  20. We identified a homozygous TACSTD2 missense mutation, c.551A>G, p.(Tyr184Cys), in the affected family members. Both parents were heterozygous for the mutation, and unaffected siblings were either heterozygous or homozygous wild-type for this allele.

Mouse (Murine) Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) interaction partners

  1. studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins.

  2. Trop2 is a regulator of self-renewal, proliferation, and transformation

  3. TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development.

  4. these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas.

  5. In human and mouse, Trop2 is highly expressed at both the transcript and protein levels on several essential normal tissues.

  6. Study also provides the first indication of a molecular signaling pathway activated by Trop2 which has important implications for cancer cell growth and survival.

  7. Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics.

TACSTD2 Antigen Profile

Protein Summary

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

Gene names and symbols associated with TACSTD2

  • tumor associated calcium signal transducer 2 (TACSTD2) antibody
  • tumor-associated calcium signal transducer 2 (Tacstd2) antibody
  • tumor associated calcium signal transducer 2 (Tacstd2) antibody
  • C80403 antibody
  • EGP-1 antibody
  • EGP1 antibody
  • GA733-1 antibody
  • GA7331 antibody
  • GP50 antibody
  • Ly97 antibody
  • M1S1 antibody
  • Prp1 antibody
  • TROP2 antibody

Protein level used designations for TACSTD2

40kD glycoprotein, identified by monoclonal antibody GA733 , cell surface glycoprotein TROP2 , cell surface glycoprotein Trop-2 , epithelial glycoprotein-1 , gastrointestinal tumor-associated antigen GA7331 , membrane component chromosome 1 surface marker 1 , membrane component, chromosome 1, surface marker 1 , pancreatic carcinoma marker protein GA733-1 , pancreatic carcinoma marker protein GA7331 , lymphocyte antigen 97 , tunor-associated calcium signal transducer 2 , parturition-related protein 1 , tumor-associated calcium signal transducer 2 , tumor associated calcium signal transducer 2

GENE ID SPECIES
4070 Homo sapiens
56753 Mus musculus
494343 Rattus norvegicus
100730427 Cavia porcellus
610286 Canis lupus familiaris
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