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anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) Antibodies

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation.

list all antibodies Gene Name GeneID UniProt
Anti-Human UHMK1 UHMK1 127933 Q8TAS1
Anti-Mouse UHMK1 UHMK1 16589 P97343
Anti-Rat UHMK1 UHMK1 246332 Q63285
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Top anti-U2AF Homology Motif (UHM) Kinase 1 Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-KIS Pab (ABIN392641) in mouse heart tissue lysate. KIS (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Uhmk1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated WB Western Blot: KIST Antibody [NBP1-31094] - HeLa S3 7.5% SDS PAGE diluted at 1:1000 100 μL Log in to see 7 to 9 Days
$514.63
Details
Dog Mouse Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB Mouse Uhmk1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Uhmk1 antibody detected the Uhmk1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$242.88
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Goat Un-conjugated ELISA   0.1 mg Log in to see 7 to 9 Days
$373.75
Details

Top referenced anti-U2AF Homology Motif (UHM) Kinase 1 Antibodies

  1. Human Polyclonal UHMK1 Primary Antibody for IHC (p), WB - ABIN392641 : Bièche, Manceau, Curmi, Laurendeau, Lachkar, Leroy, Vidaud, Sobel, Maucuer: Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human. in Brain research. Molecular brain research 2003 (PubMed)
    Show all 8 Pubmed References

  2. Cow (Bovine) Polyclonal UHMK1 Primary Antibody for ELISA - ABIN4228447 : Nakamura, Okinaka, Hirano, Ono, Sugimoto, Shigeno, Fujisawa, Shinjo, Ohnishi: KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells. in Leukemia research 2008 (PubMed)

More Antibodies against U2AF Homology Motif (UHM) Kinase 1 Interaction Partners

Human U2AF Homology Motif (UHM) Kinase 1 (UHMK1) interaction partners

  1. UHMK1 plays a role in hematopoietic cell differentiation and suppression of autonomous clonal growth of leukemia cells.

  2. genome-wide association study identified the UHMK1 gene as a novel bone mineral density locus specific to East Asians.

  3. Moreover, we showed that CATS and KIS antagonize the transactivation capacity of CALM/AF10 (show MLLT10 Antibodies).In summary, our results show that CATS interacts with and is a substrate for KIS, suggesting that KIS regulates CATS function

  4. The contribution of UHMK1 gene in schizophrenia susceptibility, was explored.

  5. We identify the kinase responsible for S10 phosphorylation as human kinase interacting stathmin (hKIS) and show that it regulates cell cycle progression in response to mitogens.

  6. KIS gene was overexpressed in NF1 (show NF1 Antibodies)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs) as compared to dermal neurofibroma which suggests a possible implication of KIS in the genesis of NF1 (show NF1 Antibodies)-associated tumors.

  7. Evidence indicating that UHMK1 may be a candidate susceptibility gene for Schizophrenia in the British population. UHMK1 is situated between previously implicated genes RGS4 (show RGS4 Antibodies) and NOS1AP (show NOS1AP Antibodies).

  8. KIS promoter is activated by serum-responsive GABP binding to Ets (show ETS1 Antibodies)-binding sites which leads to KIS gene expression, cell migration, and cell cycle progression

  9. Results show that KIS is a direct transcriptional target of FoxM1 (show FOXM1 Antibodies).

  10. Overexpression of KIS protein kinase is associated with acute myelogenous leukemia, myelodysplastic syndrome and acute lymphoblastic leukemia

Mouse (Murine) U2AF Homology Motif (UHM) Kinase 1 (UHMK1) interaction partners

  1. The absence of KIS results in a significant decrease in AMPA (show GRIA3 Antibodies) receptors in dendritic spines.

  2. disregulation of gene expression due to KIS inactivation affects specific brain functions.

  3. Uhmk1 was concentrated in the nucleus, but cycled rapidly between nucleus and cytosol.

  4. Endogenous mouse KIS was detected mainly in the nucleus of asynchronously growing cells. During serum starvation, its expression was reduced.

  5. KIS is a component of the molecular device that modulates translation in RNA-transporting granules as a result of local signals.

  6. Phosphorylation of p27Kip1 (show CDKN1B Antibodies) by KIS leads to cell-cycle progression, whereas the target sequence and the physiological relevance of KIS-mediated stathmin (show STMN1 Antibodies) phosphorylation in VSMCs

U2AF Homology Motif (UHM) Kinase 1 (UHMK1) Antigen Profile

Protein Summary

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with UHMK1

  • U2AF homology motif kinase 1 (UHMK1) antibody
  • U2AF homology motif (UHM) kinase 1 (uhmk1) antibody
  • U2AF homology motif (UHM) kinase 1 (UHMK1) antibody
  • U2AF homology motif (UHM) kinase 1 (Uhmk1) antibody
  • U2AF homology motif kinase 1 (Uhmk1) antibody
  • 4732477C12Rik antibody
  • 4930500M09Rik antibody
  • AA673513 antibody
  • AI449218 antibody
  • AU021979 antibody
  • KIS antibody
  • Kist antibody
  • P-CIP2 antibody
  • UHMK1 antibody
  • zgc:153241 antibody

Protein level used designations for UHMK1

U2AF homology motif (UHM) kinase 1 , kinase interacting stathmin , serine/threonine-protein kinase Kist , serine/threonine-protein kinase Kist-like , KIS protein kinase , PAM COOH-terminal interactor protein 2 , kinase interacting with leukemia-associated gene (stathmin) , U2AF homology motif kinase 1 , kinase interacting with stathmin , P-CIP2

GENE ID SPECIES
424369 Gallus gallus
469560 Pan troglodytes
720105 Macaca mulatta
767721 Danio rerio
100058796 Equus caballus
100408720 Callithrix jacchus
100585553 Nomascus leucogenys
100622137 Sus scrofa
127933 Homo sapiens
16589 Mus musculus
478986 Canis lupus familiaris
246332 Rattus norvegicus
538770 Bos taurus
100172072 Pongo abelii
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