Uba4p Proteins

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).

Type
  • 9
    Protein
Antigen
  • 9
Reactivity
  • 4
  • 1
  • 1
  • 1
  • 1
Application
  • 9
Host
  • 9
Binding Specificity
  • 4
  • 2
  • 1
  • 1
  • 1
Conjugate
  • 9
Protein Type
  • 9
Format
  • 9
9 Products
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCandida albicans
Application ELISA
Order details Cat. No. ABIN1631848
$3,224.83
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityYeast (Saccharomyces cerevisiae)
Application ELISA
Order details Cat. No. ABIN1663457
$3,232.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityYeast (Saccharomyces cerevisiae)
Application ELISA
Order details Cat. No. ABIN1669658
$3,232.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityYeast (Saccharomyces cerevisiae)
Application ELISA
Order details Cat. No. ABIN1671187
$3,232.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityYeast (Saccharomyces cerevisiae)
Application ELISA
Order details Cat. No. ABIN1670596
$3,232.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityAspergillus oryzae
Application ELISA
Order details Cat. No. ABIN1622960
$3,303.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityEmericella nidulans
Application ELISA
Order details Cat. No. ABIN1592917
$3,362.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityAspergillus niger
Application ELISA
Order details Cat. No. ABIN1668305
$3,362.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityAspergillus clavatus
Application ELISA
Order details Cat. No. ABIN1667970
$3,393.50
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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Uba4p (UBA4) Protein Profile

Protein Summary

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl- adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. {ECO:0000255|HAMAP-Rule:MF_03049}.

Gene names and symbols associated with Uba4p Proteins (UBA4)

  • Uba4p (UBA4) antibody
  • CaO19.2324 antibody

Protein level used designations for Uba4p Proteins (UBA4)

Ubiquitin-like protein activator 4

GENE ID SPECIES
3644432 Candida albicans SC5314