USP2 Proteins
USP2 encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily.
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Ubiquitin Specific Peptidase 2 (USP2) (AA 1-605) protein (His tag) Protein
Ubiquitin Specific Peptidase 2 (USP2) (AA 1-206) protein (His tag) Protein
Ubiquitin Specific Peptidase 2 (USP2) (AA 1-219) protein (His tag) Protein
Ubiquitin Specific Peptidase 2 (USP2) Protein Protein
Ubiquitin Specific Peptidase 2 (USP2) Protein Protein
Ubiquitin Specific Peptidase 2 (USP2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein
Ubiquitin Specific Peptidase 2 (USP2) (AA 19-113) protein (His tag) Protein
Ubiquitin Specific Peptidase 2 (USP2) (AA 1-357) protein (His tag) Protein
USP2 Protein Profile
Protein Summary
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Gene names and symbols associated with USP2
- ubiquitin specific peptidase 2 (USP2) antibody
- ubiquitin specific peptidase 2 (Usp2) antibody
- ubiquitin specific peptidase 2a (usp2a) antibody
- B930035K21Rik antibody
- UBP-t antibody
- Ubp41 antibody
- UBP46 antibody
- ubp52 antibody
- ubp66 antibody
- USP9 antibody
- zgc:92134 antibody
Protein level used designations for USP2
41 kDa ubiquitin-specific protease , deubiquitinating enzyme 2 , ubiquitin carboxyl-terminal hydrolase 2 , ubiquitin specific protease 12 , ubiquitin specific protease 9 , ubiquitin thioesterase 2 , ubiquitin-specific-processing protease 2 , ubiquitin specific protease 2 , ubiquitin thiolesterase 2 , ubiquitin-specific-processing protease testis , family of cysteine protease , ubiquitin specific protease 41 , ubiquitin specific protease 46 , ubiquitin specific protease 52 , ubiquitin specific protease 66
GENE ID | SPECIES |
---|---|
9099 | Homo sapiens |
53376 | Mus musculus |
115771 | Rattus norvegicus |
395766 | Gallus gallus |
522980 | Bos taurus |
100716929 | Cavia porcellus |
608188 | Canis lupus familiaris |
494031 | Danio rerio |
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