anti-Ubiquitin Specific Peptidase 25 (USP25) Antibodies

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Additionally we are shipping USP25 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP25 29761 Q9UHP3
USP25 304150  
USP25 30940 P57080
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Top anti-USP25 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$335.00
Details
Human Rabbit Un-conjugated WB The anti-USP25 N-term Pab (ABIN388917) is used in Western blot to detect USP25 in USP25-transfected HeLa cell lysates. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-USP25 C-term Pab (ABIN388918) is used in Western blot to detect USP25 in rat testis tissue lysate (lane 1) and USP25-transfected HeLa cell lysates (lane 2). Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using USP25 antibody. Immunohistochemistry of paraffin-embedded mouse heart using USP25 antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 11 to 13 Days
$366.77
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated ELISA, IF, IHC (p), WB   0.1 mg Log in to see 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of BxPC-3 cells, using USP25 antibody (ABIN5970690). 100 μL Log in to see 11 to 16 Days
$412.19
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL Log in to see 11 to 14 Days
$390.50
Details

Top referenced anti-USP25 Antibodies

  1. Human Polyclonal USP25 Primary Antibody for IHC (p), ELISA - ABIN545140 : Groet, Ives, Jones, Danton, Flomen, Sheer, Hrascan, Pavelic, Nizetic: Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment. in Genes, chromosomes & cancer 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal USP25 Primary Antibody for ELISA, WB - ABIN545139 : Valero, Marfany, González-Angulo, González-González, Puelles, Gonzàlez-Duarte: USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2. in Genomics 2000 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal USP25 Primary Antibody for WB - ABIN1882057 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal USP25 Primary Antibody for WB - ABIN6674203 : Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling. in PLoS ONE 2013 (PubMed)

  5. Human Polyclonal USP25 Primary Antibody for ICC, IF - ABIN4364571 : Habtemichael, Li, Alcázar-Román, Westergaard, Li, Petersen, Li, DeVries, Li, Julca-Zevallos, Wolenski, Bogan: Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes. in The Journal of biological chemistry 2019 (PubMed)

More Antibodies against USP25 Interaction Partners

Human Ubiquitin Specific Peptidase 25 (USP25) interaction partners

  1. the high stabilization of tankyrases in cultured cells by ectopic expression of a constitutive dimer of USP25 supports a biological relevance of this tetramerization/inhibition mechanism.

  2. Smurf1 overexpression decreases USP25 protein turnover, and the E3 ligase enzymatic activity of Smurf1 is required for USP25 degradation.

  3. USP25 directly interacted with tankyrases to promote their deubiquitination and stabilization and demonstrated that USP25 deficiency could promote the degradation of tankyrases and consequent stabilization of Axin to antagonize Wnt signaling

  4. Results suggest inhibition of Usp25's catalytic activity upon the non-covalent binding of SUMO2 to the Usp25 SUMO-interacting motif, and found that SUMO2 can competitively block the interaction between the Usp25 ubiquitin-binding region and its ubiquitin substrates.

  5. We detected SNPs at USP25 with associations of genome-wide significance for Inflammatory Bowel Disease.

  6. REM Sleep Behavior Disorder patients with homozygous USP25 rs2823357 progressed to synucleinopathies faster than others.

  7. Findings suggest that ubiquitin-specific protease 25 (USP25) as a VRK2 substrate that acts on TRiC deubiquitination.

  8. These findings indicate that miR-200c exerts tumor-suppressive effects for NSCLC through the suppression of USP25 expression and suggests a new therapeutic application of miR-200c in the treatment of NSCLC.

  9. USP25 is a novel deubiquitinating enzyme negatively regulating virus-induced interferon-beta production.

  10. a model where USP25 counteracts ubiquitination of ERAD substrates by the ubiquitin ligase HRD1, rescuing them from degradation by the proteasome.

  11. Studies indicate that DUBs recycle ubiquitin by processing polyubiquitin chains to generate free ubiquitin, and can be regulated by ubiquitination or phosphorylation.

  12. the second SH2 domain of SYK physically interacts with a tyrosine-rich, C-terminal region of USP25 independently of tyrosine phosphorylation

  13. characterization of alternatively spliced products and tissue-specific isoforms

  14. downregulation of USP25 gene in human lung cancer

  15. Seven amino acids in the SIM of USP25 are sufficient for SUMO2/3-specific binding and conjugation

  16. Data show that USP25m is regulated through alternative conjugation of ubiquitin (activating) or SUMO (inhibiting) to the same lysine residue (K99), which may promote the interaction with distinct intramolecular regulatory domains.

Mouse (Murine) Ubiquitin Specific Peptidase 25 (USP25) interaction partners

  1. The overexpression of TRAF3 attenuated the proinflammatory effects of USP25 knockdown in tolerized Kupffer cells.

  2. IRF7 directly binds to the two conserved IRF binding sites on the USP25 promoter to drive transcription of Usp25.

  3. Data show that the degradation of TNF receptor-associated factor 3 (TRAF3) and TNF receptor-associated Ffactor 6 (TRAF6) was accelerated in ubiquitin-specific protease 25 knockout (USP25-/-) cells after viral infection.

  4. inhibiting the degradation of TRAF3 during TLR4 activation, USP25 enables a balanced innate immune response.

  5. USP25 is a deubiquitinating enzyme (DUB) that negatively regulates IL-17-triggered signaling.

USP25 Antigen Profile

Protein Summary

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999

Gene names and symbols associated with USP25

  • ubiquitin specific peptidase 25 (USP25) antibody
  • universal stress protein UspA (RR_RS03930) antibody
  • ubiquitin specific peptidase 25 (usp25) antibody
  • ubiquitin specific peptidase 25 L homeolog (usp25.L) antibody
  • ubiquitin specific peptidase 25 (Usp25) antibody
  • MGC81666 antibody
  • USP21 antibody
  • usp25 antibody
  • wu:fi33c05 antibody
  • wu:fo67e06 antibody
  • wu:fp97a04 antibody
  • zgc:55791 antibody

Protein level used designations for USP25

ubiquitin specific peptidase 25 , ubiquitin carboxyl-terminal hydrolase 25-like , universal stress protein , ubiquitin carboxyl-terminal hydrolase 25 , ubiquitin specific protease 25 , USP on chromosome 21 , deubiquitinating enzyme 25 , ubiquitin thioesterase 25 , ubiquitin thiolesterase 25 , ubiquitin-specific processing protease 25 , ubiquitin-specific-processing protease 25 , mUSP25

GENE ID SPECIES
100458885 Pongo abelii
478387 Canis lupus familiaris
524531 Bos taurus
716923 Macaca mulatta
3127262 Haloarcula marismortui ATCC 43049
100083895 Ornithorhynchus anatinus
100348335 Oryctolagus cuniculus
100393986 Callithrix jacchus
406790 Danio rerio
418471 Gallus gallus
446581 Xenopus laevis
473918 Pan troglodytes
733977 Xenopus (Silurana) tropicalis
100229974 Taeniopygia guttata
100546482 Meleagris gallopavo
100628105 Sus scrofa
29761 Homo sapiens
304150 Rattus norvegicus
30940 Mus musculus
Selected quality suppliers for anti-USP25 (USP25) Antibodies
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