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USP25 antibody (AA 470-520)

USP25 Reactivity: Human, Mouse WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991995
  • Target See all USP25 Antibodies
    USP25 (Ubiquitin Specific Peptidase 25 (USP25))
    Binding Specificity
    • 8
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    AA 470-520
    Reactivity
    • 28
    • 10
    • 2
    Human, Mouse
    Host
    • 27
    • 1
    Rabbit
    Clonality
    • 27
    • 1
    Polyclonal
    Conjugate
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This USP25 antibody is un-conjugated
    Application
    • 23
    • 20
    • 13
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificity
    USP25 antibody is human and mouse reactive. Multiple isoforms of USP25 are known to exist.
    Purification
    USP25 antibody is affinity chromatography purified via peptide column.
    Immunogen
    USP25 antibody was raised against a 17 amino acid peptide near the center of human USP25. The immunogen is located within amino acids 470 - 520 of USP25.
    Isotype
    IgG
    Top Product
    Discover our top product USP25 Primary Antibody
  • Application Notes
    USP25 antibody can be used for detection of USP25 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    USP25 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    USP25 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    USP25 (Ubiquitin Specific Peptidase 25 (USP25))
    Alternative Name
    USP25 (USP25 Products)
    Synonyms
    USP25 antibody, zgc:55791 antibody, wu:fi33c05 antibody, wu:fo67e06 antibody, wu:fp97a04 antibody, usp25 antibody, MGC81666 antibody, usp21 antibody, USP21 antibody, ubiquitin specific peptidase 25 antibody, universal stress protein UspA antibody, ubiquitin specific peptidase 25 L homeolog antibody, USP25 antibody, RR_RS03930 antibody, usp25 antibody, usp25.L antibody, Usp25 antibody
    Background
    USP25 (ubiquitin specific peptidase 25), also known as USP21, belongs to the peptidase C19 family and is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response (1). It contains one UBA-like domain and two UIM (ubiquitin-interacting motif) repeats. Due to alternative splicing events, USP25 is expressed as two short, ubiquitously expressed isoforms and one long, muscle-specific isoform (2). The long isoform of USP25 (USP25m) is upregulated in myogenesis and is implicated in regulation of muscular differentiation and function. USP25 is a deubiquitinating enzyme (DUB) that negatively regulates IL-17-triggered signaling (3,4).
    Molecular Weight
    Predicted: 116 kDa

    Observed: 105 kDa
    Gene ID
    29761
    NCBI Accession
    NP_037528
    UniProt
    Q9UHP3
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