Ubiquitin Specific Peptidase 48 Proteins (USP48)

USP48 encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Additionally we are shipping USP48 Antibodies (46) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
USP48 84196 Q86UV5
Mouse USP48 USP48 170707 Q3V0C5
Rat USP48 USP48 362636 Q76LT8
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Top USP48 Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days

USP48 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Top referenced USP48 Proteins

  1. Human USP48 Protein expressed in Wheat germ - ABIN1324823 : Schweitzer, Naumann: CSN-associated USP48 confers stability to nuclear NF-?B/RelA by trimming K48-linked Ub-chains. in Biochimica et biophysica acta 2015 (PubMed)

More Proteins for Ubiquitin Specific Peptidase 48 (USP48) Interaction Partners

Human Ubiquitin Specific Peptidase 48 (USP48) interaction partners

  1. the catalytic USP domain of USP48 interacts with the N-terminal region of the Rel homology domain (RHD) of RelA.

  2. USP48 and BRAF mutations have a role in Cushing's disease

  3. USP48 inactivation reduces chromosomal instability of Fanconi anemia (FA)-defective cells. Our results highlight a role for USP48 in controlling DNA repair and suggest it as a potential target that could be therapeutically exploited for FA.

  4. In contrast to other deubiquitinating enzymes (DUBs) that have been previously implicated in the regulation of Mdm2 protein stability, USP48 did not induce Mdm2 stabilization by significantly reducing Mdm2 ubiquitination levels.

  5. down-regulation of USP48 increases E-cadherin expression and epithelial barrier integrity through reducing TRAF2 stability

  6. study reveals that the USP48-Gli1 regulatory axis is critical for glioma cell proliferation and glioblastoma tumorigenesis.

  7. Data suggest that ubiquitin specific protease-48 (USP48) promotes genome stability by antagonizing BRCA1 E3 ligase function.

  8. this study demonstrates that USP48 controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB/RelA in the nucleus.

  9. Northern blot analysis revealed a single USP31 transcript of approximately 4 kb, which was primarily expressed in the testis and lung.

  10. The Overexpression of USP31 in HEK 293T cells inhibited TNFalpha, CD40, LMP1, TRAF2, TRAF6 and IKKbeta-mediated NF-kappaB activation, but did not inhibit Smad-mediated transcription activation.

  11. data demonstrate a crucial role for the dynamic interaction between D3R and USP48 in the regulation of NHE3 expression and function

USP48 Protein Profile

Protein Summary

This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with USP48

  • ubiquitin specific peptidase 48 (USP48)
  • ubiquitin specific peptidase 48 (Usp48)
  • ubiquitin specific peptidase 48 (usp48)
  • 2810449C13Rik protein
  • AI115503 protein
  • BC021769 protein
  • D330022K21Rik protein
  • MGC135142 protein
  • RAP1GA1 protein
  • synUSP protein
  • Usp31 protein
  • USP48 protein
  • zgc:112364 protein

Protein level used designations for USP48

deubiquitinating enzyme 48 , ubiquitin carboxyl-terminal hydrolase 48 , ubiquitin specific protease 31 , ubiquitin specific protease 48 , ubiquitin thioesterase 48 , ubiquitin thiolesterase 48 , ubiquitin-specific-processing protease 48 , synaptic ubiquitin-specific protease , ubiquitin specific peptidase 48 , ubiquitin carboxyl-terminal hydrolase 48-like

84196 Homo sapiens
170707 Mus musculus
362636 Rattus norvegicus
456602 Pan troglodytes
769457 Gallus gallus
100141158 Bos taurus
478198 Canis lupus familiaris
100023231 Monodelphis domestica
100058232 Equus caballus
100087092 Ornithorhynchus anatinus
100145207 Xenopus (Silurana) tropicalis
100332674 Danio rerio
100402610 Callithrix jacchus
100440156 Pongo abelii
100464072 Ailuropoda melanoleuca
100603457 Nomascus leucogenys
100625904 Sus scrofa
100725391 Cavia porcellus
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