Ubiquitin Specific Peptidase 8 Proteins (USP8)

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Additionally we are shipping USP8 Antibodies (93) and USP8 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
USP8 9101 P40818
Rat USP8 USP8 296121  
Mouse USP8 USP8 84092 Q80U87
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Top USP8 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$860.20
Details
Insect cells (Sf9) Human His tag   25 μg Log in to see 5 to 8 Days
$770.50
Details
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$656.00
Details

USP8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,

More Proteins for Ubiquitin Specific Peptidase 8 (USP8) Interaction Partners

Human Ubiquitin Specific Peptidase 8 (USP8) interaction partners

Mouse (Murine) Ubiquitin Specific Peptidase 8 (USP8) interaction partners

USP8 Protein Profile

Protein Summary

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.

Gene names and symbols associated with USP8

  • ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109)
  • ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369)
  • ubiquitin specific peptidase 8 (USP8)
  • ubiquitin specific peptidase 8 (Usp8)
  • AI574262 protein
  • AW557536 protein
  • HumORF8 protein
  • mKIAA0055 protein
  • Ubpy protein

Protein level used designations for USP8

ubiquitin carboxyl-terminal hydrolase 8 , ubiquitin-specific-processing protease 8 , ubiquitin specific peptidase 8 , ubiquitin carboxyl-terminal hydrolase 8-like , deubiquitinating enzyme 8 , hUBPy , ubiquitin isopeptidase Y , ubiquitin specific protease 8 , ubiquitin thioesterase 8 , ubiquitin thiolesterase 8 , putative deubiquitinating enzyme

GENE ID SPECIES
9310109 Arabidopsis lyrata subsp. lyrata
10031598 Arthroderma gypseum CBS 118893
100408559 Callithrix jacchus
100437819 Pongo abelii
9101 Homo sapiens
296121 Rattus norvegicus
84092 Mus musculus
100157546 Sus scrofa
415451 Gallus gallus
100351436 Oryctolagus cuniculus
100720255 Cavia porcellus
Selected quality suppliers for USP8 Proteins (USP8)
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