Ubiquitin-Like Modifier Activating Enzyme 6 Proteins (UBA6)

Modification of proteins with ubiquitin (UBB\; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). Additionally we are shipping UBA6 Antibodies (77) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBA6 55236 A0AVT1
Mouse UBA6 UBA6 231380 Q8C7R4
Rat UBA6 UBA6 305268  
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Top UBA6 Proteins at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$932.80
Details

UBA6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6) Interaction Partners

Human Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6) interaction partners

  1. Polyubiquitination and proteasomal degradation of ezrin and CUGBP1 require Uba6, but not Uba1, and that Uba6 is involved in the control of ezrin localization and epithelial morphogenesis. These data suggest that distinctive substrate pools exist for Uba1 and Uba6 that reflect non-redundant biological roles for Uba6.

  2. this study revealed a novel function of LMO2 involving in the regulatory hierarchy of UBA6-USE1-FAT10ylation pathway by targeting the E1 enzyme UBA6.

  3. Interstitial microdeletions including the chromosome band 4q13.2 and the UBA6 gene as possible causes of intellectual disability and behavior disorder.

  4. Diminished ubiquitylation phenotype observed in enteropathogenic Escherichia coli infected cells corresponds to a strong reduction in the abundance of both Ube1 and Uba6.

  5. Data indicate the potential role of cytokine-induced FAT10 expression in regulating Uba6 pathways.

  6. UBE1L2 is a novel E1 enzyme specific for ubiquitin

  7. Human Uba6 and Ube1 have distinct preferences for E2 charging in vitro, and their specificity depends in part on their C-terminal ubiquitin-fold domains, which recruit E2s

  8. The identification of an E1-like protein, termed E1-L2, that activates both ubiquitin and another ubiquitin-like protein, FAT10, is reported.

  9. Ubiquitin-like modifier activating enzyme 6 activates not only ubiquitin, but also the ubiquitin-like modifier FAT10[review]

Mouse (Murine) Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6) interaction partners

  1. Uba6 and Use1 promote proteasomal turnover of Ube3a in mouse embryo fibroblasts (MEFs) and catalyze Ube3a ubiquitylation in vitro.

  2. The identification of an E1-like protein, termed E1-L2, that activates both ubiquitin and another ubiquitin-like protein, FAT10, is reported.

UBA6 Protein Profile

Protein Summary

Modification of proteins with ubiquitin (UBB\; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007

Gene names and symbols associated with UBA6

  • ubiquitin like modifier activating enzyme 6 (UBA6)
  • ubiquitin-like modifier activating enzyme 6 (Uba6)
  • 4930542H01 protein
  • 5730469D23Rik protein
  • AU021846 protein
  • AW124799 protein
  • E1-L2 protein
  • MOP-4 protein
  • RGD1308324 protein
  • Ube1l2 protein

Protein level used designations for UBA6

UBA6, ubiquitin-activating enzyme E1 , monocyte protein 4 , ubiquitin-activating enzyme 6 , ubiquitin-activating enzyme E1-like 2 , ubiquitin-activating enzyme E1-like protein 2 , ubiquitin-like modifier-activating enzyme 6

GENE ID SPECIES
55236 Homo sapiens
231380 Mus musculus
305268 Rattus norvegicus
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