anti-Unc-45 Homolog B (C. Elegans) (UNC45B) Antibodies

UNC45B plays a role in myoblast fusion and sarcomere organization (Price et al., 2002 [PubMed 12356907]).[supplied by OMIM, Mar 2008].. Additionally we are shipping UNC45B Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UNC45B 217012 Q8CGY6
UNC45B 146862 Q8IWX7
UNC45B 303373  
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Top anti-UNC45B Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$319.00
Details
Bat Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$610.50
Details
Dog Goat Un-conjugated EIA, WB   0.1 mg 4 to 8 Days
$462.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB Western blot analysis in mouse lung tissue lysates (35ug/lane). UNC45B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Goat Un-conjugated ELISA, WB UNC45B polyclonal antibody  (0.3 ug/mL) staining of human skeletal muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 11 to 12 Days
$374.67
Details
Human Mouse Un-conjugated WB Western Blot analysis of UNC45B expression in transfected 293T cell line by UNC45B MaxPab polyclonal antibody.Lane 1: UNC45B transfected lysate(93.5 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
$440.00
Details
Human Goat APC ELISA, WB   100 μL 16 Days
$760.57
Details
Human Goat FITC ELISA, WB   100 μL 16 Days
$760.57
Details
Human Goat Alkaline Phosphatase (AP) ELISA, WB   100 μL 16 Days
$760.57
Details

Top referenced anti-UNC45B Antibodies

  1. Human Polyclonal UNC45B Primary Antibody for WB - ABIN530920 : Yoshida, Sho, Nanjo, Takahashi, Kobayashi, Kawamura, Honma, Komatsu, Sugita, Yamauchi, Hosoi, Ito, Masuda: Weaving hypothesis of cardiomyocyte sarcomeres: discovery of periodic broadening and narrowing of intercalated disk during volume-load change. in The American journal of pathology 2010 (PubMed)

  2. Human Polyclonal UNC45B Primary Antibody for ELISA, WB - ABIN4364358 : Landsverk, Li, Hutagalung, Najafov, Hoppe, Barral, Epstein: The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans. in The Journal of cell biology 2007 (PubMed)

More Antibodies against UNC45B Interaction Partners

Mouse (Murine) Unc-45 Homolog B (C. Elegans) (UNC45B) interaction partners

  1. UNC-45B and Hsp90 involved in sarcomere function

  2. vertebrate Unc45 isoforms clearly demonstrates a direct role for Unc45 in Hsp90-mediated myosin motor domain folding and highlights major differences between the isoforms in substrate specificity and mechanism

  3. mammalian Unc45b is a cytosolic protein that forms a stable complex with Hsp90, selectively binds the unfolded conformation of the myosin motor domain, and promotes motor domain folding

Human Unc-45 Homolog B (C. Elegans) (UNC45B) interaction partners

  1. We have characterized a human UNC45B mutation in a Danish family with autosomal dominant cataract developing in early childhood.

  2. temperature-dependent structural changes in the UCS chaperone domain of UNC-45B that occur within a physiologically relevant heat-shock range.

Zebrafish Unc-45 Homolog B (C. Elegans) (UNC45B) interaction partners

  1. The transcriptional up-regulation of unc45b, hsp90aa1.1 and smyd1b is specific to zebrafish mutants with myosin folding defects, and is not triggered in other zebrafish myopathy models

  2. Results indicate co-expression and co-regulation of Unc45b and non-muscle myosins (NMMs) in myogenic tissue.

  3. There is no functional redundancy between Unc45a and Unc45b in vivo.

  4. isolation and expression pattern of zebrafish unc45r

  5. Steif/Unc-45b interacts with the chaperone Hsp90a in vitro. The two genes are co-expressed in the skeletal musculature.

  6. In response to stress or damage to the myofiber, Unc45b and Hsp90a dissociate from the Z line and transiently associate with myosin.

Pig (Porcine) Unc-45 Homolog B (C. Elegans) (UNC45B) interaction partners

  1. Different genotypes of the CMYA4 gene are significantly associated with the backfat thickness of the area between sixth and seventh ribs (p < 0.05) and backfat thickness at the shoulder (p < 0.05).

UNC45B Antigen Profile

Protein Summary

UNC45B plays a role in myoblast fusion and sarcomere organization (Price et al., 2002

Gene names and symbols associated with UNC45B

  • unc-45 myosin chaperone B S homeolog (unc45b.S) antibody
  • unc-45 myosin chaperone B (unc45b) antibody
  • unc-45 myosin chaperone B (UNC45B) antibody
  • unc-45 myosin chaperone B (Unc45b) antibody
  • AA445617 antibody
  • cb393 antibody
  • CMYA4 antibody
  • D230041A13Rik antibody
  • MGC80931 antibody
  • SMUNC45 antibody
  • Unc-45B antibody
  • UNC45 antibody
  • unc45r antibody
  • wu:fa05a03 antibody
  • wu:fa10f03 antibody
  • wu:fb37f02 antibody
  • wu:fb96f06 antibody
  • wu:fc10f04 antibody

Protein level used designations for UNC45B

unc-45 homolog B , sarcomeric myosin heavy chain chaperone , unc-45 homolog B (C. elegans) , protein unc-45 homolog B-like , UNC-45B , cardiomyopathy associated 4 , protein unc-45 homolog B , striated muscle UNC45 , UNC45-related protein , fb37f02 , unc-45B , cardiomyopathy-associated 4

GENE ID SPECIES
447296 Xenopus laevis
493194 Xenopus (Silurana) tropicalis
715419 Macaca mulatta
100483697 Ailuropoda melanoleuca
100586571 Nomascus leucogenys
217012 Mus musculus
146862 Homo sapiens
303373 Rattus norvegicus
480606 Canis lupus familiaris
100715234 Cavia porcellus
266640 Danio rerio
535385 Bos taurus
417527 Gallus gallus
100058135 Equus caballus
100134956 Sus scrofa
100346230 Oryctolagus cuniculus
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