anti-V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) Antibodies

ERG encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. Additionally we are shipping V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Proteins (11) and V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ERG 2078 P11308
ERG 170909  
ERG 13876 P81270
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Top anti-V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Antibodies at antibodies-online.com

Showing 10 out of 136 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ERG Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185550 (10µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ERG Antibody Titration:  1.0ug/ml  Positive Control:  Jurkat cell lysate Host:  Rabbit  Target Name:  ERG  Sample Type:  Jurkat  Lane A:  Primary Antibody  Lane B:  Primary Antibody + Blocking Peptide  Primary Antibody Concentration:  1.25ug/mL  Peptide Concentration:  1.0ug/mL  Lysate Quantity:  25ug/lane  Gel Concentration:  12% 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of human pancreatic cancer cell line, using ERG, antibody at 1:50 dilution. WB Image Sample (50 ug of whole cell lysate) A: mouse brain 10% SDS PAGE antibody diluted at 1:10000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Dog Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western blot analysis of extracts from MCF7  using ERG antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276640 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600 was used as secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using ERG antibody. 100 μL Log in to see 16 Days
$366.77
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p) Human Prostate (formalin-fixed, paraffin-embedded) stained with ERG antibody ABIN295774 at 10 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-ERG antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details

Top referenced anti-V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Antibodies

  1. Human Polyclonal ERG Primary Antibody for IHC (p), IHC - ABIN250916 : Tomlins, Rhodes, Perner, Dhanasekaran, Mehra, Sun, Varambally, Cao, Tchinda, Kuefer, Lee, Montie, Shah, Pienta, Rubin, Chinnaiyan: Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Interaction Partners

Human V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. TMPRSS2:ERG has been proved to be the most specific biomarker for clinically significant Prostate Cancer (specificity 93.2%, sensitivity 24.3%).

  2. confirm a mutual cooperative role of ERG and PTEN in the pathogenesis of prostate cancer, particularly for homozygous PTEN deletion

  3. endothelial transcriptional effector activated downstream of Ang1 to promote Notch signalling and vascular stability

  4. Nine primary prostate cancers that developed metachronous bone metastasis samples showed TMPRSS2-ERG fusions, which were associated with increased ERG expression at immunohistochemistry. mTOR pathway activation was documented in 6 patients

  5. Data indicate a significant prognostic role for assessing transcriptional regulator ERG (ERG) and phosphatase and tensin homolog protein (PTEN) in men with prostate cancer.

  6. There was no statistically significant difference in the expression of the ERG between patients and controls. Also, no correlation was detected between the expression of this gene and age of onset, disease duration and Expanded Disability Status Scale.

  7. Here, the authors show that ERG, through its physical interaction with androgen receptor, induces AR aggregation and endoplasmic reticulum stress in the prostate glands of ERG transgenic mice.

  8. Our results suggested that reduced expression of miR-1271 may be involved in the ERG expression and that miR-1271 could be a therapeutic target for ERG-positive prostate cancer patients

  9. Evaluating the association between ERG expression and pathologic factors.

  10. despite of their well-known adverse role in prognosis of AML, neither BAALC nor ERG expression levels at diagnosis had effect on survival of AML patients who underwent allo-HSCT.

  11. ERG expression is lost in liver endothelial cells from cirrhotic patients with fibrosis related to alcoholic liver disease or primary biliary cirrhosis and inversely correlates with increased markers of endothelial-to-mesenchymal transition.

  12. ERG expression is of limited prognostic value in acute myeloid leukemia.

  13. Our findings indicate that TGF-beta signaling is a major determinant of EMT in T/E overexpressing LNCaP cells.

  14. Findings reveal that PCa-associated ERG can interact and co-occupy with BRD4 in the genome, and suggest this druggable interaction is critical for ERG-mediated cell invasion and PCa progression.

  15. this work provides novel insights in the regulation of ERG protein stability in prostate cancer

  16. Study reveals that miR-200b/a/429 is an ERG target gene, which implicates an important role in TMPRSS2/ERG-dependent PCa development.

  17. ERG and SOX9 are potential biomarkers for prediction of response to docetaxel treatment in metastatic castration-resistant prostate cancer patients.

  18. A potential novel function of TMPRSS2-ERG as a major regulator of IGF1R gene expression.

  19. Study shows that T2E fusion transcripts are associated with higher levels of AMACR mRNA in patients with atypical small acinar proliferation (ASAP) which represents an indicator of risk for prostate cancer in patients with ASAP.

  20. TMPRSS2-ERG may have a role in progression of prostate neoplasms and in alteration of the metabolic profile

Xenopus laevis V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. KLF2 and ERG associate in a physical complex and the two proteins synergistically activate transcription of Flk1.

Zebrafish V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. fli1, and etsrp, demonstrated that erg and fli1 act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin

  2. A combination of gain-of-function and loss-of-function studies suggested a redundant yet specific role for erg in both angioblast specification/proliferation and early angiogenesis, and a synergistic interaction with the critical ETS factor etsrp.

Mouse (Murine) V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. ERG balances TGFbeta signalling through the SMAD1 and SMAD3 pathways, protecting the endothelium from endothelial-to-mesenchymal transition and consequent liver fibrosis in mice via a SMAD3-dependent mechanism.

  2. Reduced Erg dosage impairs survival of hematopoietic stem and progenitor cells.

  3. loss of ERG and FLI1 might contribute to the pathogenesis of vascular lung complications through the induction of inflammation.

  4. Combined, these data suggest a possible pathway linking GDF5, ERG and downstream factors in the processes of chondrocyte differentiation during articular joint formation.

  5. Our study reveals that ERG has essential and cell autonomous roles in endothelial cell development and blood vessel maintenance.

  6. We show that the gene expression signature specifically attributable to trisomy of Erg in the murine model is strongly correlated with gene expression changes in human Down syndrome hematopoietic cells.

  7. Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

  8. ERG plays a critical role in coordinating the balance between self-renewal and differentiation of HSCs.

  9. ERG activates the transcriptional program regulated by YAP1 of the Hippo signaling pathway and found that prostate-specific activation of either ERG or YAP1 in mice induces similar transcriptional changes and results in age-related prostate tumors.

  10. ERG and APLNR are essential for endothelial homeostasis in venules in the lung and that perturbation in ERG-APLNR signaling is crucial for the development of pulmonary veno-occlusive disease.

  11. Regulation of Erg by TGF-beta was confirmed in these cells.

  12. Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.

  13. Expression of ERG and ETV1 correlated with higher AR transcriptional output in PTEN-deficient prostate cancer specimens.

  14. E-twenty-six (ETS) transcription factors Ets related gene (Erg) and Ets1 are the most common sites for transposon insertion in SB-induced JAK2V617F-positive erythroleukemias

  15. Erg is required for the maintenance of the core EnMT regulatory factors that include Snail1 and Snail2 by binding to their promoter and intronic regions

  16. in mice, Erg overexpression induces the development of not only lymphoid leukemia but also erythro-megakaryocytic leukemia

  17. Erg is a critical regulator of adult hematopoietic stem cells, essential for maintaining self-renewal at times of high HSC cycling.

  18. ERG is capable of promoting the development of leukemia and is crucial for its maintenance.

  19. from the fetal period, ERG acts as a direct upstream regulator of Gata2 and Runx1 gene activity

  20. the expression of the VE-statin/egfl7 gene in endothelial cells and the specific importance of ETS and GATA factors

V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) Antigen Profile

Protein Summary

This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with ERG

  • ERG, ETS transcription factor (ERG) antibody
  • ERG, ETS transcription factor (Erg) antibody
  • v-ets avian erythroblastosis virus E26 oncogene homolog L homeolog (erg.L) antibody
  • v-ets avian erythroblastosis virus E26 oncogene homolog (erg) antibody
  • v-ets avian erythroblastosis virus E26 oncogene homolog S homeolog (erg.S) antibody
  • ETS transcription factor (Erg) antibody
  • D030036I24Rik antibody
  • ERG antibody
  • erg-3 antibody
  • erg_A antibody
  • erg_E antibody
  • p55 antibody
  • zgc:103429 antibody

Protein level used designations for ERG

TMPRSS2/ERG fusion , ets-related , transcriptional regulator ERG , transcriptional regulator ERG (transforming protein ERG) , v-ets avian erythroblastosis virus E26 oncogene related , v-ets erythroblastosis virus E26 oncogene homolog , v-ets erythroblastosis virus E26 oncogene like , avian erythroblastosis virus E-26 (v-ets) oncogene related , vascular ETS factor , erg1 , erg gene (erg_E) , v-ets erythroblastosis virus E26 oncogene homolog (avian) , transcriptional regulator Erg

GENE ID SPECIES
2078 Homo sapiens
170909 Rattus norvegicus
378618 Xenopus laevis
494073 Danio rerio
535231 Bos taurus
100223535 Taeniopygia guttata
378619 Xenopus laevis
100216056 Xenopus (Silurana) tropicalis
473995 Pan troglodytes
100604101 Nomascus leucogenys
13876 Mus musculus
374146 Gallus gallus
100713723 Cavia porcellus
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