anti-Vesicle-Associated Membrane Protein 3 (VAMP3) Antibodies

Human Vesicle-Associated Membrane Protein 3 (VAMP3) interaction partners

1. Knockdown of VAMP3 and SNAP23 reduces endothelial secretion of miR-126-3p and miR-200a-3p, as well as the proliferation, migration, and suppression of contractile markers in smooth muscle cells caused by vascular endothelial cell-coculture.

2. The authors found that activation of dendritic cells by bacterial lipopolysaccharide leads to increased Forster resonance energy transfer-fluorescence of fluorescently labeled syntaxin 4 with VAMP3 specifically at the plasma membrane, indicating increased SNARE complex formation, whereas FRET with other tested SNAREs was unaltered.

3. RABGEF1 mediates recycling endosome fusion with GAS-containing autophagosome-like vacuoles through the STX6-VAMP3-VTI1B complex; SNAREs are involved in autophagosome formation in response to bacterial infection

4. The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse.

5. phosphatidylinositol 4-kinase IIalpha knockdown inhibited vesicle-associated membrane protein 3 trafficking to perinuclear membranes and impaired the rate of VAMP3-mediated recycling of the transferrin receptor

6. highlight the role that VAMP3 and VAMP7 play in selection of the pathways leading to generation of ultrastructurally different LC3 compartments

7. Liquid chromatography-MS/MS analysis showed that the HHV-6 gM/gN complex interacts with the v-SNARE protein, vesicle-associated membrane protein 3 (VAMP3).

8. These results indicated that Uukuniemi virus relies on VAMP3 for penetration, providing an indication of added complexity in the trafficking of viruses through the endocytic network.

9. Genome-wide expression profiling identified the transcription of ADIPOR1, VAMP3 and C11ORF10 to be correlated with decreased ANRIL expression in a time-dependent manner.

10. Data suggest VAMP3 and SNAP23 (synaptosomal-associated protein 23 kDa) participate in interleukin-1beta-, interleukin-1 receptor-, calcium signaling-dependent secretion/exocytosis of interleukin-6 and tumor necrosis factor alpha from synoviocytes.

11. Data suggest a new integrin trafficking pathway in which endocytosed integrins are transported from VAMP3-containing recycling endosomes to STX6-containing trans-Golgi network before being recycled to the plasma membrane.

12. mutation of the Godzilla ubiquitylation target lysines on VAMP3 abrogates the formation of enlarged endosomes induced by either Godzilla or RNF167.

13. Endothelial cells specifically select VAMP 3 over VAMP8 to cooperate with syntaxin 4 and SNAP23 in the Ca(2+)-triggered fusion of Weibel-Palade bodies with the plasma membrane.

14. the importance of VAMP3 in the trafficking of matrix metalloproteinases during degradation of extracellular matrix substrates and subsequent cellular invasion

15. TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways.

16. Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells

17. VAMP-3 and VAMP-8 are present in human platelets and are required for granule secretion.

18. These results do not suggest that a common genetic variant at VAMP2 or VAMP3 contributes to the development of bipolar affective disorder in German patients.

19. VAMP3-dependent integrin trafficking is crucial in cell migration and cell adhesion to laminin.

Rhesus Monkey Vesicle-Associated Membrane Protein 3 (VAMP3) interaction partners

1. phosphatidylinositol 4-kinase IIalpha knockdown inhibited vesicle-associated membrane protein 3 trafficking to perinuclear membranes and impaired the rate of VAMP3-mediated recycling of the transferrin receptor

Mouse (Murine) Vesicle-Associated Membrane Protein 3 (VAMP3) interaction partners

1. platelets are capable of a range of endocytosis steps, with VAMP-3 being pivotal in these processes.

2. VAMP3 is required for normal NKCC2 expression, renal function, and blood pressure.

3. The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse.

4. Although a slight decrease in the rate of recovery of surviving bacteria was observed between 12 h and 36 h post-infection with Brucella melitensis, this was not significant indicating that VAMP3 is not involved in Brucella survival.

5. Protein kinase D activates GLUT4 translocation via a VAMP3-dependent trafficking step.

6. This important SNARE complex facilitates macrophage adhesion, spreading, and persistent macrophage migration on fibronectin through the delivery of VAMP3-positive membrane with its cargo to expand the plasma membrane.

7. VAMP3 mediates fusion of recycling endosome-derived vesicles with the oligodendroglial plasma membrane in the course of the secretory pathway

8. Cellubrevin alterations and Mycobacterium tuberculosis phagosome maturation arrest.

9. SNARE proteins (cellubrevin, syntaxin 4) are involved in late steps of GLUT4 translocation in adipocyte differentiation.

10. The requirement of vamp3 in phagocytosis in macrophages was determined in vamp3 knockout mice

11. cellubrevin/VAMP-3 is not a requirement for the platelet release reaction in mice.

12. From these results we concluded that cellubrevin-dependent membrane trafficking is involved in TEX101-transport to the surface of male germ cells.

13. transport vesicles containing VAMP3 have distinct membrane fusion kinetics with domains of the plasma membrane that present different t-SNARE proteins.

14. Data show that in VAMP-8-deficient cells constitutive vesicular trafficking mechanisms are perturbed as indicated by increased SNARE complex formation between VAMP-3 and SNAP-23.

15. Simultaneous disruption of VAMPs 2, 3 and 8 completely inhibited insulin-stimulated GLUT4 insertion into the plasma membrane.