anti-Vitamin K-dependent protein C (PROC) Antibodies

PROC encodes a vitamin K-dependent plasma glycoprotein. Additionally we are shipping PROC Kits (68) and PROC Proteins (37) and many more products for this protein.

Gene Name	GeneID	UniProt
PROC	25268	P31394
PROC	19123	P33587
PROC	5624	P04070

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Top anti-PROC Antibodies at antibodies-online.com

Showing 10 out of 216 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN3044486	Human	Rabbit	Un-conjugated	IHC (p), WB	100 μg	Log in to see	4 to 6 Days	$280.00	Details
ABIN2776947	Horse	Rabbit	Un-conjugated	IHC, WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN2790305	Human	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$319.00	Details
ABIN2774395	Goat	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN2776946	Cow	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$229.00	Details
ABIN2706876	Human	Rabbit	Un-conjugated	WB	200 μL	Log in to see	13 to 14 Days	$487.50	Details
ABIN2856681	Human	Rabbit	Un-conjugated	WB	100 μL	Log in to see	3 to 4 Days	$466.18	Details
ABIN3187756	Human	Rabbit	Un-conjugated	ELISA, IHC (p), WB	100 μL	Log in to see	16 Days	$181.73	Details
ABIN574202	Human	Goat	Un-conjugated	ELISA, IEP, IHC, IHC (p)	250 μg	Log in to see	11 to 14 Days	$727.83	Details
ABIN320670	Bat	Rabbit	Un-conjugated	WB	100 μg	Log in to see	11 to 14 Days	$493.17	Details

More product categories related to PROC Antibody

Top referenced anti-PROC Antibodies

Human Polyclonal PROC Primary Antibody for IHC (p), WB - ABIN3044486 : Liu, An, Liu, Li, Tang, Chen: Mouse lung slices: An ex vivo model for the evaluation of antiviral and anti-inflammatory agents against influenza viruses. in Antiviral research 2015 (PubMed)
Show all 10 Pubmed References
Cow (Bovine) Polyclonal PROC Primary Antibody for EIA, RIA - ABIN613777 : Satou, Nishi, Hishinuma, Hosoda, Kangawa, Sugimoto: Identification of activated protein C as a ghrelin endopeptidase in bovine plasma. in The Journal of endocrinology 2014 (PubMed)

More Antibodies against PROC Interaction Partners

Mouse (Murine) Vitamin K-dependent protein C (PROC) interaction partners

Data show that activated protein C signals via protease activated receptors PAR2 (show F2RL1 Antibodies)/PAR3 (show F2RL2 Antibodies) to expand Treg cells, mitigating the disease in mice.
insulin (show INS Antibodies) and aPC (show APC Antibodies) converge on a common spliced-X-box binding protein-1 (show XBP1 Antibodies) (sXBP1) signaling pathway to maintain endoplasmic reticulum (ER) homeostasis.
loss of the convertase furin (show FURIN Antibodies) or PC5 (show PCSK5 Antibodies)/6 in hepatocytes results in a approximately 30% decrease in APC (show APC Antibodies) levels, with no significant contribution from PACE4 (show PCSK6 Antibodies). We conclude that prior convertase cleavage of protein C in hepatocytes is critical for its thrombin (show F2 Antibodies) activation.
APC (show APC Antibodies) modifies pulmonary fibrosis by limiting thrombin (show F2 Antibodies)-dependent macrophage recruitment.
Small interfering RNA-mediated silencing of protein C in apolipoprotein E (show APOE Antibodies)-deficient mice creates a condition that allows the occurrence of spontaneous atherothrombosis.
These findings reveal a novel biological function and mechanism of the protein C pathway in which protein S and the aPC (show APC Antibodies)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (show APC Antibodies) in the context of endotoxemia and infection
activated PC-EPCR-PAR1 signaling promotes hematopoietic stem cell retention in bone marrow.
impaired EPCR (show PROCR Antibodies)/protein C-binding interactions not only result in procoagulant and proinflammatory effects, but also impact hematopoiesis
SOD prevents thrombomodulin (show THBD Antibodies) methionine oxidation, promotes protein C activation, and protects against arterial and venous thrombosis in mice.
sPLA2 (show PLA2G2A Antibodies)-V plays a thrombogenic role by impairing the ability of EPCR (show PROCR Antibodies) to promote protein C activation.

Human Vitamin K-dependent protein C (PROC) interaction partners

The fusion protein recapitulates the functional and structural properties of the thrombin (show F2 Antibodies)-thrombomodulin (show THBD Antibodies) complex, prolongs the clotting time by generating pharmacological quantities of activated protein C and effectively diagnoses protein C deficiency in human plasma.
Polymorphisms of F2, PROC, PROZ, and F13A1 Genes are Associated With Recurrent Spontaneous Abortion in Chinese Han Women.
Laboratory tests and direct sequencing of PROC and SERPINC1 (show SERPINC1 Antibodies) were conducted for the patient and his family members. Coagulation tests revealed that the patient presented type I antithrombin (show SERPINC1 Antibodies) deficiency combined with decreased protein C activity resulting from a small insertion mutation c.848_849insGATGT in SERPINC1 (show SERPINC1 Antibodies) and a short deletion variant c.572_574delAGA in PROC.
Using protein C-factor VII (show TH Antibodies) chimera demonstrate that APC (show APC Antibodies) light chain amino acid residues outside the EPCR (show PROCR Antibodies)-binding site enable cytoprotective PAR1 (show MARK2 Antibodies) signaling.
We recently identified a venous thrombosis patient whose plasma level of protein C antigen is normal, but its anticoagulant activity is only 34 % of the normal level. Genetic analysis revealed that the proband and her younger brother carry a novel heterozygous mutation c.346G>A, p.Gly74Ser (G74S) in PROC.
Developed functional protein S assays that measure both the activated protein C- and TFPI (show TFPI Antibodies)-cofactor activities of protein S in plasma, which are hardly if at all affected by the FV Leiden mutation.
Protein C seems inversely associated with mortality in patients with advanced prostate, lung and pancreatic cancer. Further research should validate protein C as a biomarker for mortality, and explore the effects of protein C on progression of cancer.
Genetically higher protein C was associated with a lower risk of ischaemic heart disease.
EPCR (show PROCR Antibodies) occupancy recruits G-protein coupled receptor kinase 5 (show GRK5 Antibodies), thereby inducing beta-arrestin-2 (show ARRB2 Antibodies) biased PAR1 (show MARK2 Antibodies) signaling by both APC (show APC Antibodies) and thrombin (show F2 Antibodies). In
A novel mutation of A309V in PROC was determined in a family of two patients with late onset protein C deficiency

Cow (Bovine) Vitamin K-dependent protein C (PROC) interaction partners

Activated protein c is a ghrelin (show GHRL Antibodies) endopeptidase.
Activated protein C(APC (show APC Antibodies)) combined with protein S(PS) had significant antithrombotic effect. APC (show APC Antibodies) combined with PS prolonged clotting time. Dependence on APC (show APC Antibodies)-cofactor activity of PS for expression of anticoagulant activity by APC (show APC Antibodies).

PROC Antigen Profile

Protein Summary

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Gene names and symbols associated with PROC

protein C (inactivator of coagulation factors Va and VIIIa), a (proca) antibody
protein C, inactivator of coagulation factors Va and VIIIa (PROC) antibody
protein C (inactivator of coagulation factors Va and VIIIa) (PROC) antibody
protein C, inactivator of coagulation factors Va and VIIIa S homeolog (proc.S) antibody
protein C, inactivator of coagulation factors Va and VIIIa (proc) antibody
vitamin K-dependent protein C (CpipJ_CPIJ000393) antibody
vitamin K-dependent protein C (CpipJ_CPIJ002754) antibody
vitamin K-dependent protein C (CpipJ_CPIJ003717) antibody
vitamin K-dependent protein C (CpipJ_CPIJ003718) antibody
vitamin K-dependent protein C (CpipJ_CPIJ014440) antibody
vitamin K-dependent protein C (CpipJ_CPIJ018032) antibody
vitamin K-dependent protein C (CpipJ_CPIJ018737) antibody
protein C, inactivator of coagulation factors Va and VIIIa (Proc) antibody
protein C (Proc) antibody

APC antibody
MGC64425 antibody
PC antibody
PROC antibody
PROC1 antibody
si:ch1073-188c16.3 antibody
THPH3 antibody
THPH4 antibody
zgc:63987 antibody

Protein level used designations for PROC

protein C , procl , anticoagulant protein C , vitamin K-dependent protein C , protein C (inactivator of coagulation factors Va and VIIIa) , vitamin K-dependent protein C-like , autoprothrombin IIA , blood coagulation factor XIV , inactivator of coagulation factors Va, VIII , catalytic region , protein C (precursor of vitamin K-dependent serine protease)

GENE ID	SPECIES
393327	Danio rerio
395085	Gallus gallus
459593	Pan troglodytes
100302329	Ovis aries
380116	Xenopus laevis
548476	Xenopus (Silurana) tropicalis
100231143	Taeniopygia guttata
100448857	Pongo abelii
6031231	Culex quinquefasciatus
6033948	Culex quinquefasciatus
6035053	Culex quinquefasciatus
6035054	Culex quinquefasciatus
6047546	Culex quinquefasciatus
6052150	Culex quinquefasciatus
6052641	Culex quinquefasciatus
25268	Rattus norvegicus
19123	Mus musculus
5624	Homo sapiens
281428	Bos taurus
101096161	Felis catus
476104	Canis lupus familiaris
100051306	Equus caballus
396954	Sus scrofa
100009223	Oryctolagus cuniculus
699077	Macaca mulatta

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Fax:	+1 888 205 9894 (Toll-free)
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Show all anti-Vitamin K-dependent protein C (PROC) Antibodies with Pubmed References