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WFDC2 encodes a protein that is a member of the WFDC domain family. Additionally we are shipping WFDC2 Proteins (26) and WFDC2 Kits (22) and many more products for this protein.
Showing 10 out of 155 products:
Human Monoclonal WFDC2 Primary Antibody for ELISA, WB - ABIN564522
Yuan, Duan, Yang, Luo, Xi: Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonance. in International journal of nanomedicine 2012
Human Polyclonal WFDC2 Primary Antibody for ELISA, WB - ABIN4276002
Huhtinen, Suvitie, Hiissa, Junnila, Huvila, Kujari, Setälä, Härkki, Jalkanen, Fraser, Mäkinen, Auranen, Poutanen, Perheentupa: Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts. in British journal of cancer 2009
Data show that serum human epididymis protein 4 (HE4) levels were significantly positively associated with renal fibrosis in chronic kidney disease (CKD) patients.
serum HE4 level was a marker of poor prognosis in lung cancer patients
This review summarizes data regarding the detection and alteration of HE4 in urine samples collected from ovarian cancer patients and controls.
HE4 is a prognostic marker in endometrial cancer
HE4 levels correspond to clinical and FIGO stage of endometrial cancer
HE4 is elevated less frequently than CA125 (show MUC16 Antibodies) in benign adnexal tumors, regardless of age or menopausal status
HE4 expression in biopsy material from endometrial hyperplasia can be monitored and regulated by progestin. Changes in the expression of HE4 during progestin therapy regimens can predict therapy response or indicate progestin resistance for medium- and low-risk endometrial hyperplasia.
Serum HE4 levels were significantly elevated in children and adults with cystic fibrosis (show S100A8 Antibodies) (CF) compared to controls. Abnormal but lower HE4 concentrations were found in cases of severe bronchitis, asthma, pneumonia, and bronchiectasis. HE4 mRNA levels were significantly upregulated in CF vs. non-CF airway biopsy specimens.
Human epididymis protein 4 induces chemoresistance against anti-cancer drugs and activates the AKT (show AKT1 Antibodies) and Erk (show EPHB2 Antibodies) pathways to enhance tumor survival. Human epididymis protein 4 expression in ovarian cancer tissue is associated with a worse prognosis for epithelial ovarian cancer patients.
This study found that increased serum HE4 is independently associated with the development of Lupus Nephritis and Chronic Kidney Disease in Systemic Lupus Erythematosus patients.
Causal testing implicates Wfdc2 and Hdac3 (show HDAC3 Antibodies) as novel genes affecting high density lipoprotein levels
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
WAP four-disulfide core domain 2
, WAP four-disulfide core domain 3
, WAP four-disulfide core domain protein 2
, WAP domain containing protein HE4-V4
, epididymal protein 4
, epididymal secretory protein E4
, epididymis-specific, whey-acidic protein type, four-disulfide core
, major epididymis-specific protein E4
, putative protease inhibitor WAP5
, WAP domain-containing protein HE4
, epididymal secretory protein 4
, epididymal protein BE-20