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WFDC2 encodes a protein that is a member of the WFDC domain family.
Showing 10 out of 168 products:
Human Monoclonal WFDC2 Primary Antibody for ELISA, WB - ABIN564522
Yuan, Duan, Yang, Luo, Xi: Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonance. in International journal of nanomedicine 2012
Human Polyclonal WFDC2 Primary Antibody for ELISA, WB - ABIN4276002
Huhtinen, Suvitie, Hiissa, Junnila, Huvila, Kujari, Setälä, Härkki, Jalkanen, Fraser, Mäkinen, Auranen, Poutanen, Perheentupa: Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts. in British journal of cancer 2009
The significant effect of the normalization of the HE4 marker after therapy and 50% reduction of HE4 levels before interval cytoreductive surgery on PFS and OS confirmed that HE4 might be an independent prognostic factor of treatment response.
HE4 could help with the differentiation of prognostically varied patient groups as well as with the decision-making process associated with the development of individual treatment plans
Studied serum levels of Parkinson's disease-associated protein 7 (DJ-1 (show PARK7 Antibodies)) and human epididymis protein 4 (HE4) in endometrial cancer (EC) patients and healthy controls. The median serum concentrations of DJ-1 (show PARK7 Antibodies) and HE4 were found to be significantly higher in EC patients compared to controls.
HE4 is a biomarker for ovarian cancer recurrence [review]
Numerous studies indicated that HE4 is able to promote cancer progression and drug resistance. These observations strongly suggest that HE4 may play a significant role in cancer recurrence through its bioactivity in the regulation of malignant behavior at the cellular level. Overall, available data shows that high serum HE4 levels correlate well with ovarian cancer recurrence. [review]
High HE4 expression is associated with adnexal malignancy.
Architect CA 125 (show MUC16 Antibodies) II and HE4 values in Chinese women presenting with a pelvic mass
Review/Meta-analysis: urine HE4 has diagnostic value in detecting ovarian cancer.
HE4 seems to be superior to CA125 (show MUC16 Antibodies) in the detection of recurrent disease.
Data show that serum human epididymis protein 4 (HE4) levels were significantly positively associated with renal fibrosis in chronic kidney disease (CKD) patients.
Causal testing implicates Wfdc2 and Hdac3 (show HDAC3 Antibodies) as novel genes affecting high density lipoprotein levels
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
WAP four-disulfide core domain 2
, WAP four-disulfide core domain 3
, WAP four-disulfide core domain protein 2
, WAP domain containing protein HE4-V4
, epididymal protein 4
, epididymal secretory protein E4
, epididymis-specific, whey-acidic protein type, four-disulfide core
, major epididymis-specific protein E4
, putative protease inhibitor WAP5
, WAP domain-containing protein HE4
, epididymal secretory protein 4
, epididymal protein BE-20