WFDC2 Products
(WAP Four-Disulfide Core Domain 2 (WFDC2))
Categories
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008].
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Featured WFDC2 Categories
WFDC2 Antibodies
High quality antibodies with extensive validation data.
WFDC2 ELISA Kits
Reliable ELISA kits for a wide range of species.
WFDC2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended WFDC2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, WB, IHC (p)
Validations
- (6)
Cat. No.
ABIN5519074
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7175671
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN1491389
Quantity
100 μL
Datasheet
Datasheet
Recommended WFDC2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962650
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960523
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6976023
Quantity
96 tests
Datasheet
Datasheet
Recommended WFDC2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Dog
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274791
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1325310
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125722
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our WFDC2 products
: "Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer." in: Cancer, (2019) (PubMed).: "Value of HE4 Combined with Cancer Antigen 125 in the Diagnosis of Endometrial Cancer." in: Pakistan journal of medical sciences, Vol. 33, Issue 4, pp. 1013-1017, (2017) (PubMed).
: "Detection of Human Epididymis Protein 4 (HE4) in Human Serum Samples Using a Specific Monoclonal Antibody-Based Sandwich Enzyme-Linked Immunosorbent Assay (ELISA)." in: Journal of clinical laboratory analysis, Vol. 30, Issue 5, pp. 581-9, (2017) (PubMed).
: "Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing." in: Analytical and bioanalytical chemistry, (2015) (PubMed).
: "HE4 (WFDC2) gene overexpression promotes ovarian tumor growth." in: Scientific reports, Vol. 4, pp. 3574, (2014) (PubMed).
: "Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis." in: Nature medicine, Vol. 19, Issue 2, pp. 227-31, (2013) (PubMed).
: "Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonance." in: International journal of nanomedicine, Vol. 7, pp. 2921-8, (2012) (PubMed).
: "Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts." in: British journal of cancer, Vol. 100, Issue 8, pp. 1315-9, (2009) (PubMed).
: "The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma." in: Cancer research, Vol. 63, Issue 13, pp. 3695-700, (2003) (PubMed).
: "A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors." in: Biology of reproduction, Vol. 45, Issue 2, pp. 350-7, (1992) (PubMed).
Synonyms and alternative names related to WFDC2
WAP four-disulfide core domain 2 (WFDC2), WAP four-disulfide core domain 2 (wfdc2), WAP four-disulfide core domain 2 (Wfdc2), 1600023A02Rik, BE-20, CE4, dJ461P17.6, EDDM4, HE4, re4, si:ch211-153a8.3, WAP5, WFDC2, WFDC3Protein level used designations for WFDC2
- WAP four-disulfide core domain 2
- WAP four-disulfide core domain 3
- WAP four-disulfide core domain protein 2
- WAP domain containing protein HE4-V4
- epididymal protein 4
- epididymal secretory protein E4
- epididymis-specific, whey-acidic protein type, four-disulfide core
- major epididymis-specific protein E4
- putative protease inhibitor WAP5
- WAP domain-containing protein HE4
- epididymal secretory protein 4
- epididymal protein BE-20
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