Within Bgcn Homolog (Drosophila) Proteins
Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post- transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.
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Within Bgcn Homolog (Drosophila) (WIBG) (AA 1-204) protein (His tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) (AA 1-203) protein (His tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) (Transcript Variant 2) protein (His tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) (AA 1-204) protein (GST tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) (AA 1-204) protein (His tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) Protein Protein
Within Bgcn Homolog (Drosophila) (WIBG) (AA 1-204) protein (His tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) (AA 1-204) protein (His tag) Protein
Within Bgcn Homolog (Drosophila) (WIBG) Protein Profile
Protein Summary
Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post- transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions (By similarity).
Gene names and symbols associated with WIBG
- Partner of Y14 and Mago (Pym) antibody
- Wibg protein (wibg) antibody
- PYM homolog 1, exon junction complex associated factor L homeolog (pym1.L) antibody
- PYM homolog 1, exon junction complex associated factor (PYM1) antibody
- PYM homolog 1, exon junction complex associated factor (Pym1) antibody
- PYM homolog 1, exon junction complex associated factor (pym1) antibody
- A030010B05Rik antibody
- BEST:HL05757 antibody
- CG10330 antibody
- CG30176 antibody
- Dmel\\CG30176 antibody
- Pym antibody
- UD3 antibody
- zgc:65891 antibody
- zgc:77281 antibody
Protein level used designations for WIBG
CG30176-PA , undefined 3 , wibg-PA , Protein wibg homolog , partner of Y14 and mago , protein wibg homolog
| GENE ID | SPECIES |
|---|---|
| 37780 | Drosophila melanogaster |
| 692986 | Bombyx mori |
| 494688 | Xenopus laevis |
| 84305 | Homo sapiens |
| 78428 | Mus musculus |
| 787259 | Bos taurus |
| 393566 | Danio rerio |
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