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YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. Additionally we are shipping YY1 Transcription Factor Antibodies (146) and YY1 Transcription Factor Kits (6) and many more products for this protein.
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YY1 is essential for Xenopus development in neural ectoderm differentiation, neural crest specification and directing neural crest mesenchyme formation by blocking slug
Yin Yang 1 transcription factor assembly into messenger ribonucleoprotein particles requires direct RNA binding activity
Results show that the YY1-RNA interaction is highly stable, and that YY1 possesses the ability to interact with structurally divergent RNA substrates.
results suggest that YY1a regulates PS receptor expression that linked to function of PSR (show JMJD6 Proteins)-phagocyte mediated apoptotic cell engulfment during development
YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 (show DDIT3 Proteins) expression.
Study demonstrated that beta-arrestin1 (show ARRB1 Proteins) is critically involved in zebrafish primitive hematopoiesis, where beta-arrestin1 (show ARRB1 Proteins) binds to and sequesters the PcG recruiter YY1, thus relieving PcG-mediated repression of cdx4-hox (show MSH2 Proteins) pathway.
expression of miR (show MLXIP Proteins)-192-5p was negatively correlated with that of YY1 in bladder cancer tissues
YY1 promoted glioma cell proliferation and miR218 could inhibit glioma cell proliferation by targeting YY1.
miR (show MLXIP Proteins)-30a acts in a feedback loop to modulate the pro-autophagic activities of YY1.
Data suggest a role for YY1 transcription factor (YY1) in transcriptional activity on inactive X (Xi) in general through sequence-specific binding, and its involvement at superloop anchors.
Results suggest that up-regulation of YY1 is closely associated with the progression of cervical squamous cell carcinoma, and YY1 may play an important role in the pathogenesis of cervical cancer by modulating the expression of E-cadherin (show CDH1 Proteins) and HPV16 E6.
Results show that histone deacetylase 1 (HDAC1 (show HDAC1 Proteins)) expression was positively correlated with YY1 transcription factor (YY1) in hepatocellular carcinoma (HCC (show FAM126A Proteins)) cell lines and primary tumor tissues.
Authors found that YY1 and STAT1 (show STAT1 Proteins) were upregulated in ox-LDL-stimulating macrophages followed by translocation in the nucleus and binding to the transcriptional promoter region of miR (show MLXIP Proteins)-29a, thus leading to the increase of miR (show MLXIP Proteins)-29a expression.
results support a model in which YY1 acts as an architectural protein to connect developmentally regulated looping interactions; the location of YY1-mediated interactions may be demarcated in development by a preexisting topological framework created by constitutive CTCF (show CTCF Proteins)-mediated interactions.
High expression of nuclear YY1 was significantly associated with higher AJCC stage and small vessel invasion.
This is the first report on the status of YY1 T372R in insulinoma (show RPS15 Proteins) cases of Indian origin.
The interaction of repressor proteins Trim28 (show TRIM28 Proteins) and YY1 are involved in the silencing of Moloney murine leukemia virus.
This study provides novel evidence for a role of miR (show MLXIP Proteins)-34c in inhibiting myoblasts proliferation by repressing YY1.
These observations support a role for YY1 meditating and/or regulating the interaction of OCT4 (show POU5F1 Proteins) and SOX2 (show SOX2 Proteins) at a posttranscriptional level.
these results demonstrate that YY1 overexpression is sufficient to maintain a Cardiac Progenitor Cell phenotype.
these results suggested that the basal promoter activity of the mIRF-3 gene is regulated by transcription factors Egr2 (show EGR2 Proteins) and YY1 in NIH3T3 cells
DNA binding domain of YY1 is necessary for X-chromosome inactivation in activated B cells, as ex-vivo YY1 deletion results in loss of inactive X (Xi) chromosome heterochromatin marks and up-regulation of X-linked genes.
Transcriptome analysis revealed that YY1 is required for mitochondrial gene expression, and ultrastructural analysis confirmed compromised mitochondrial integrity in the mutant intestine.
regulates broad general processes throughout all stages of B-cell differentiation: normally activates genes involved in mitochondrial bioenergetics; normally down-regulates genes involved in transcription, mRNA splicing, NF-kappaB (show NFKB1 Proteins) signaling pathways, the AP-1 (show JUN Proteins) transcription factor network, chromatin remodeling, cytokine signaling pathways, cell adhesion, and cell proliferation
Results indicate that YY1 plays an important role in regulating the balance between dark zone and light zone cells in germinal center (GCs (show UGCG Proteins)) and between survival and death of GC B (show NPR2 Proteins) cells.
YY1 is required for germinal center B cell development.
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
YY1 transcription factor
, YY1 transcription factor, like
, transcription factor YY1
, Yin Yang 1
, INO80 complex subunit S
, Yin and Yang 1 protein
, delta transcription factor
, transcriptional repressor protein YY1
, GLI-Krupple related protein
, UCR-motif DNA-binding protein
, UCRBP transcription factor
, yin and yang 1