YY1 Transcription Factor Proteins (YY1)

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. Additionally we are shipping YY1 Transcription Factor Antibodies (145) and YY1 Transcription Factor Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
YY1 7528 P25490
YY1 22632 Q00899
Rat YY1 YY1 24919  
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Top YY1 Transcription Factor Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 13 to 16 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human His tag   10 μg Log in to see 15 to 16 Days
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
Escherichia coli (E. coli) Human DYKDDDDK Tag   10 μg Log in to see 1 to 2 Days

YY1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for YY1 Transcription Factor (YY1) Interaction Partners

Xenopus laevis YY1 Transcription Factor (YY1) interaction partners

  1. YY1 is essential for Xenopus development in neural ectoderm differentiation, neural crest specification and directing neural crest mesenchyme formation by blocking slug

  2. Yin Yang 1 transcription factor assembly into messenger ribonucleoprotein particles requires direct RNA binding activity

  3. Results show that the YY1-RNA interaction is highly stable, and that YY1 possesses the ability to interact with structurally divergent RNA substrates.

Zebrafish YY1 Transcription Factor (YY1) interaction partners

  1. Study reveals for the first time that miR-7a1 functions to regulate molecular pathways involved in NAFLD/NASH phenotypes in zebrafish models. YY1b is a novel downstream target of miR-7a1 and is beneficial for lipid anabolism in zebrafish.

  2. results suggest that YY1a regulates PS receptor expression that linked to function of PSR-phagocyte mediated apoptotic cell engulfment during development

  3. YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression.

  4. Study demonstrated that beta-arrestin1 is critically involved in zebrafish primitive hematopoiesis, where beta-arrestin1 binds to and sequesters the PcG recruiter YY1, thus relieving PcG-mediated repression of cdx4-hox pathway.

Human YY1 Transcription Factor (YY1) interaction partners

  1. In conclusion, YY1 may play an important regulatory role in ATP6V1A expression with potential mechanistic and clinical implications in gastric cancer.

  2. Data show that MiR-147b targets the 3' untranslated region (3'UTR) of Yin Yang 1 (YY1).

  3. Results show that YY1 is phosphorylated by c-Abl kinase at tyrosine residue 254 and that this phosphorylation likely modulates its transcriptional activity.

  4. YY1-CDKN3-MDM2/P53-P21 axis is involved in pancreatic tumorigenesis

  5. The repression of TBX21 expression by high-affinity binding of YY1 to the -1993C allele may contribute to a decreased development of AIH-1 via suppression of type 1 immunity.

  6. expression of miR-192-5p was negatively correlated with that of YY1 in bladder cancer tissues

  7. YY1 promoted glioma cell proliferation and miR218 could inhibit glioma cell proliferation by targeting YY1.

  8. miR-30a acts in a feedback loop to modulate the pro-autophagic activities of YY1.

  9. Data suggest a role for YY1 transcription factor (YY1) in transcriptional activity on inactive X (Xi) in general through sequence-specific binding, and its involvement at superloop anchors.

  10. Results suggest that up-regulation of YY1 is closely associated with the progression of cervical squamous cell carcinoma, and YY1 may play an important role in the pathogenesis of cervical cancer by modulating the expression of E-cadherin and HPV16 E6.

  11. Results show that histone deacetylase 1 (HDAC1) expression was positively correlated with YY1 transcription factor (YY1) in hepatocellular carcinoma (HCC) cell lines and primary tumor tissues.

  12. Authors found that YY1 and STAT1 were upregulated in ox-LDL-stimulating macrophages followed by translocation in the nucleus and binding to the transcriptional promoter region of miR-29a, thus leading to the increase of miR-29a expression.

  13. results support a model in which YY1 acts as an architectural protein to connect developmentally regulated looping interactions; the location of YY1-mediated interactions may be demarcated in development by a preexisting topological framework created by constitutive CTCF-mediated interactions.

  14. High expression of nuclear YY1 was significantly associated with higher AJCC stage and small vessel invasion.

  15. This is the first report on the status of YY1 T372R in insulinoma cases of Indian origin.

  16. YY1 promotes proliferation and migration with suppression of apoptosis via directly inhibiting MYCT1 in laryngeal cancer cells, suggesting that YY1 is a useful target as a potential oncogene in laryngeal cancer development and progression.

  17. These data suggested that YY1 may be important for apoptosis induction via the regulation of Fas during sepsis. Therefore, Fas may be a potential therapeutic target to prevent MOD through regulation of YY1 expression. Furthermore, YY1 and Fas expression in PBMCs may be used to as prognostic markers.

  18. Study shows that the ubiquitously expressed transcription factor Yin Yang 1 (YY1) contributes to enhancer-promoter structural interactions in a manner analogous to DNA interactions mediated by CTCF.

  19. YY1 was over-expressed in RA which can bind to the promotor of IL-6 to introduce IL-6 expression, contributing to the inflammation of RA via stimulation of Th17 differentiation.

  20. YY1 promotes apoptosis via upregulating Bax transcription and subsequent activation of Bax by translocation from the cytosol to the mitochondrial membrane.

Mouse (Murine) YY1 Transcription Factor (YY1) interaction partners

  1. this study shows that YY1 can control AID-mediated mutagenesis in mice

  2. YY1 was progressively up-regulated in BV2 microglial cells stimulated with lipopolysaccharide (LPS), which was dependent on the transactivation function of nuclear factor kappa B (NF-kappaB). Furthermore, YY1 knockdown notably inhibited LPS-induced the activation of NF-kappaB signaling and interleukin-6 (IL-6) expression in BV-2cells.

  3. The interaction of repressor proteins Trim28 and YY1 are involved in the silencing of Moloney murine leukemia virus.

  4. This study provides novel evidence for a role of miR-34c in inhibiting myoblasts proliferation by repressing YY1.

  5. These observations support a role for YY1 meditating and/or regulating the interaction of OCT4 and SOX2 at a posttranscriptional level.

  6. these results demonstrate that YY1 overexpression is sufficient to maintain a Cardiac Progenitor Cell phenotype.

  7. these results suggested that the basal promoter activity of the mIRF-3 gene is regulated by transcription factors Egr2 and YY1 in NIH3T3 cells

  8. DNA binding domain of YY1 is necessary for X-chromosome inactivation in activated B cells, as ex-vivo YY1 deletion results in loss of inactive X (Xi) chromosome heterochromatin marks and up-regulation of X-linked genes.

  9. Transcriptome analysis revealed that YY1 is required for mitochondrial gene expression, and ultrastructural analysis confirmed compromised mitochondrial integrity in the mutant intestine.

  10. regulates broad general processes throughout all stages of B-cell differentiation: normally activates genes involved in mitochondrial bioenergetics; normally down-regulates genes involved in transcription, mRNA splicing, NF-kappaB signaling pathways, the AP-1 transcription factor network, chromatin remodeling, cytokine signaling pathways, cell adhesion, and cell proliferation

  11. Results indicate that YY1 plays an important role in regulating the balance between dark zone and light zone cells in germinal center (GCs) and between survival and death of GC B cells.

  12. YY1 is required for germinal center B cell development.

  13. Dp71 expression in hepatic cells is carried out, in part, by YY1-, Sp1- and Sp3-mediated transcription from the Dp71 promoter.

  14. this study shows that YY1 regulates the formation of terminal-effector CD8+ T cell fates

  15. that yin yang 1 strongly localizes in the spermatogonial stem cells and co-localizes heterogeneously with CP2c to permit spermatogenesis

  16. YY1 and SP1 independently and cooperatively govern the Mesp1 expression during embryogenesis.

  17. YY1 regulates lung CCL4 transcription in pulmonary tuberculosis.

  18. YY1 functions as a critical regulator of thymocyte survival and that it does so by suppressing the expression of p53.

  19. YY1 interrupts Foxp3-dependent target gene expression by physically interacting with Foxp3 and by directly binding to the Foxp3 target genes.

  20. This study showed that that Linc-YY1 regulates skeletal myogenesis and uncover a previously unappreciated mechanism of gene regulation by lincRNA.

YY1 Transcription Factor (YY1) Protein Profile

Protein Summary

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

Gene names and symbols associated with YY1 Transcription Factor Proteins (YY1)

  • YY1 transcription factor L homeolog (yy1.L)
  • YY1 transcription factor b (yy1b)
  • YY1 transcription factor (YY1)
  • YY1 transcription factor (yy1)
  • transcriptional repressor protein YY1 (LOC100304682)
  • YY1 transcription factor S homeolog (yy1.S)
  • YY1 transcription factor (Yy1)
  • YY1 transcription factor a (yy1a)
  • YY2 transcription factor (YY2)
  • AW488674 protein
  • DELTA protein
  • fb59g10 protein
  • FIII protein
  • INO80S protein
  • LOC494431 protein
  • LOC100304682 protein
  • MGC83714 protein
  • NF-E1 protein
  • UCRBP protein
  • wu:fa16g07 protein
  • wu:fb59g10 protein
  • xyy1 protein
  • YIN-YANG-1 protein
  • yy1 protein
  • yy1-a protein
  • yy1l protein
  • zgc:64207 protein

Protein level used designations for YY1 Transcription Factor Proteins (YY1)

YY1 transcription factor , YY1 transcription factor, like , transcription factor YY1 , Yin Yang 1 , INO80 complex subunit S , YY-1 , Yin and Yang 1 protein , delta transcription factor , transcriptional repressor protein YY1 , GLI-Krupple related protein , UCR-motif DNA-binding protein , UCRBP transcription factor , yin and yang 1

394372 Xenopus laevis
406394 Danio rerio
453159 Pan troglodytes
494431 Ovis aries
100126440 Xenopus (Silurana) tropicalis
100304682 Ictalurus punctatus
100022685 Monodelphis domestica
100229529 Taeniopygia guttata
447228 Xenopus laevis
7528 Homo sapiens
611171 Canis lupus familiaris
534353 Bos taurus
22632 Mus musculus
24919 Rattus norvegicus
322397 Danio rerio
423455 Gallus gallus
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